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Great Point Partners LLC

13F filer · CIK 0001281446
Reported Aug 14, 2026
Net seller this quarter
13F portfolio value$529MU.S. long equity reported on 13F
Positions3710 new · 12 closed
Net flow last quarter-$54.9MBuys minus sells
Top 10 positions weight43.0%Concentration

Holdings

13F · last 4 quarters free
Scroll for earlier quarters
CompanyValue% of portfolio% of companyPOSITION CHANGE qoq %First reported
Q2 2026Reported Aug 14, 202637 positions
VORVor Biopharma Inc.$31.3M5.91%3.12%-2.9%Q4 2025
ABVXAbivax S.A.$27.2M5.15%0.26%Not reportedQ4 2023
VERAVera Therapeutics, Inc.$25.8M4.87%0.84%+201.4%Q1 2026
ZURAZura Bio Ltd$24.9M4.70%4.42%Not reportedQ2 2023
ALMSAlumis Inc.$24.1M4.55%Not reportedNot reportedQ1 2026
SLGLSol-Gel Technologies Ltd.$20.3M3.84%9.85%Not reportedQ1 2026
DFTXDefinium Therapeutics, Inc.$20M3.78%0.32%NewQ2 2026
ANNXAnnexon, Inc.$20M3.78%2.34%+40.0%Q1 2026
ORKAOruka Therapeutics, Inc.$17.4M3.30%0.30%Not reportedQ3 2024
MLTXMoonLake Immunotherapeutics$16.7M3.15%1.16%+71.2%Q2 2022
SGMTSagimet Biosciences Inc.$15.7M2.97%6.62%NewQ2 2026
CTNMContineum Therapeutics, Inc.$15.1M2.85%3.99%+15.2%Q4 2025
IMMXImmix Biopharma, Inc.$13.2M2.49%1.79%+265.0%Q1 2026
CLYMClimb Bio, Inc.$13M2.46%1.74%-25.0%Q3 2024
AMLXAmylyx Pharmaceuticals, Inc.$12.6M2.38%0.63%-60.0%Q4 2022
NKTRNektar Therapeutics$12.2M2.31%0.86%-44.7%Q3 2019
NGNENeurogene Inc.$11.1M2.09%2.22%-29.6%Q4 2023
LBRXLB Pharmaceuticals Inc$10.3M1.95%1.11%+5.7%Q1 2026
IRDOpus Genetics, Inc.$8.1M1.53%2.38%+507.4%Q1 2026
EPRXEupraxia Pharmaceuticals Inc.$7.93M1.50%2.31%Not reportedQ3 2025
DRUGBright Minds Biosciences Inc.$7.69M1.45%1.44%-50.2%Q1 2026
IFRXInflaRx N.V.$6.82M1.29%4.21%Not reportedQ1 2021
RLMDRelmada Therapeutics, Inc.$5.83M1.10%0.79%Not reportedQ4 2021
JATTJATT II Acquisition Corp.$5.68M1.07%27.78%NewQ2 2026
CGEMCullinan Therapeutics, Inc.$5.46M1.03%0.47%Not reportedQ4 2025
ALTAltimmune, Inc.$5.29M1.00%0.90%NewQ2 2026
AMANAmanat Acquisition Corp.$5.08M0.96%Not reportedNewQ2 2026
RZLTRezolute, Inc.$4.95M0.94%0.99%Not reportedQ4 2024
SLNSilence Therapeutics plc$4.94M0.93%0.32%-55.9%Q4 2021
PALIPalisade Bio, Inc.$4.78M0.90%1.32%-32.9%Q1 2026
EVMNEvommune, Inc.$4.32M0.82%0.90%Not reportedQ4 2025
SCYXScynexis Inc$3.84M0.73%9.49%0.0%Q1 2026
ELVNEnliven Therapeutics, Inc.$3.55M0.67%0.10%NewQ2 2026
HUMAHumacyte, Inc.$2.93M0.55%1.35%Not reportedQ1 2026
RNTXRein Therapeutics, Inc.$2.68M0.51%3.00%NewQ2 2026
DBVTDBV Technologies S.A.$2.57M0.49%0.05%Not reportedQ3 2016
PMNProMIS Neurosciences Inc.$1.13M0.21%0.96%-76.8%Q3 2024
Q1 2026Reported May 15, 202639 positions
APGEApogee Therapeutics, Inc.$31.5M7.23%0.50%Not reportedQ3 2023
VORVor Biopharma Inc.$31.2M7.18%3.23%+27.7%Q4 2025
ZURAZura Bio Ltd$25.1M5.77%4.44%+10.5%Q2 2023
AMLXAmylyx Pharmaceuticals, Inc.$24.3M5.59%1.58%Not reportedQ4 2022
NKTRNektar Therapeutics$22.8M5.23%1.55%+50.2%Q3 2019
SLGLSol-Gel Technologies Ltd.$21.7M5.00%9.85%NewQ1 2026
ALMSAlumis Inc.$18.9M4.33%Not reportedNewQ1 2026
DRUGBright Minds Biosciences Inc.$16.1M3.69%2.88%NewQ1 2026
ANNXAnnexon, Inc.$13.9M3.18%1.67%NewQ1 2026
KALVKalVista Pharmaceuticals, Inc.$13.6M3.12%1.32%-1.6%Q4 2021
IMVTImmunovant, Inc.$13.6M3.11%0.27%-27.3%Q1 2025
JBIOJade Biosciences, Inc.$13.6M3.11%1.95%+19.6%Q2 2025
CTNMContineum Therapeutics, Inc.$10.5M2.40%3.46%0.0%Q4 2025
ZBIOZenas BioPharma, Inc.$10.2M2.35%0.84%NewQ1 2026
NGNENeurogene Inc.$10.1M2.32%3.20%+42.9%Q4 2023
MLTXMoonLake Immunotherapeutics$9.32M2.14%0.95%Not reportedQ2 2022
CLYMClimb Bio, Inc.$9.14M2.10%2.79%+36.2%Q3 2024
ORKAOruka Therapeutics, Inc.$8.99M2.07%0.37%Not reportedQ3 2024
EPRXEupraxia Pharmaceuticals Inc.$8.69M2.00%2.31%Not reportedQ3 2025
VERAVera Therapeutics, Inc.$8.02M1.84%0.31%NewQ1 2026
EVMNEvommune, Inc.$7.47M1.72%0.90%Not reportedQ4 2025
LBRXLB Pharmaceuticals Inc$7.4M1.70%1.05%NewQ1 2026
CMPXCompass Therapeutics, Inc.$7.14M1.64%0.75%NewQ1 2026
SCYXScynexis Inc$6.93M1.59%12.17%NewQ1 2026
PALIPalisade Bio, Inc.$5.96M1.37%2.03%NewQ1 2026
CNTXContext Therapeutics Inc.$5.86M1.35%2.44%-52.2%Q2 2024
RLMDRelmada Therapeutics, Inc.$5.86M1.35%0.80%Not reportedQ4 2021
SLNSilence Therapeutics plc$5.38M1.24%0.72%+26.3%Q4 2021
UNCYUnicycive Therapeutics, Inc.$5.24M1.20%3.16%Not reportedQ3 2024
TENXTenax Therapeutics, Inc.$5.23M1.20%1.35%Not reportedQ3 2014
PMNProMIS Neurosciences Inc.$4.72M1.08%4.14%Not reportedQ3 2024
CGEMCullinan Therapeutics, Inc.$4.26M0.98%0.49%-52.7%Q4 2025
IMMXImmix Biopharma, Inc.$3.19M0.73%0.66%NewQ1 2026
RZLTRezolute, Inc.$2.9M0.67%0.99%Not reportedQ4 2024
PHVSPharvaris N.V.$2.34M0.54%0.13%Not reportedQ3 2025
HUMAHumacyte, Inc.$2.28M0.52%1.69%NewQ1 2026
AVTXAvalo Therapeutics, Inc.$1.86M0.43%0.51%Not reportedQ1 2023
ALKSAlkermes plc.$1.77M0.41%0.03%Not reportedQ2 2022
IRDOpus Genetics, Inc.$1.48M0.34%0.45%NewQ1 2026
Q4 2025Reported Feb 17, 202629 positions
APGEApogee Therapeutics, Inc.$28.2M9.15%0.55%+23.0%Q3 2023
AMLXAmylyx Pharmaceuticals, Inc.$21.1M6.85%1.59%+2.9%Q4 2022
ZURAZura Bio Ltd$20M6.48%5.18%Not reportedQ2 2023
IRONDisc Medicine, Inc.$19.9M6.44%0.66%NewQ4 2025
RAPTRAPT Therapeutics, Inc.$19.7M6.38%2.10%Not reportedQ3 2022
IMVTImmunovant, Inc.$19.1M6.18%0.37%+50.0%Q1 2025
SLNOSoleno Therapeutics Inc$18.5M6.00%0.77%+77.8%Q3 2025
VORVor Biopharma Inc.$17.9M5.81%3.54%NewQ4 2025
DNTHDianthus Therapeutics, Inc.$14.4M4.68%0.81%+31.7%Q1 2024
JBIOJade Biosciences, Inc.$12.4M4.03%1.63%+27.5%Q2 2025
KALVKalVista Pharmaceuticals, Inc.$11.1M3.59%1.35%Not reportedQ4 2021
CTNMContineum Therapeutics, Inc.$9.14M2.96%3.46%NewQ4 2025
EPRXEupraxia Pharmaceuticals Inc.$9.06M2.94%2.31%Not reportedQ3 2025
FULCFulcrum Therapeutics, Inc.$9.05M2.93%1.20%NewQ4 2025
NKTRNektar Therapeutics$8.91M2.89%1.03%-29.8%Q3 2019
UPBUpstream Bio, Inc.$8.15M2.64%0.55%Not reportedQ4 2024
NGNENeurogene Inc.$7.21M2.34%2.26%-21.7%Q4 2023
RAREUltragenyx Pharmaceutical Inc.$6.9M2.24%0.31%Not reportedQ4 2022
CNTXContext Therapeutics Inc.$6.89M2.23%5.10%Not reportedQ2 2024
CGEMCullinan Therapeutics, Inc.$6.56M2.13%1.05%NewQ4 2025
EVMNEvommune, Inc.$5.56M1.80%1.03%NewQ4 2025
ORKAOruka Therapeutics, Inc.$5.56M1.80%0.38%Not reportedQ3 2024
SLNSilence Therapeutics plc$4.91M1.59%0.57%Not reportedQ4 2021
UNCYUnicycive Therapeutics, Inc.$4.6M1.49%3.60%Not reportedQ3 2024
CLYMClimb Bio, Inc.$3.92M1.27%2.05%Not reportedQ3 2024
SANASana Biotechnology, Inc.$2.85M0.92%0.26%Not reportedQ3 2025
PHVSPharvaris N.V.$2.3M0.75%0.13%-46.6%Q3 2025
AVTXAvalo Therapeutics, Inc.$2.26M0.73%0.67%Not reportedQ1 2023
RZLTRezolute, Inc.$2.25M0.73%1.00%-61.2%Q4 2024
Q3 2025Reported Nov 14, 202528 positions
AMLXAmylyx Pharmaceuticals, Inc.$23.1M9.53%1.55%-15.0%Q4 2022
RZLTRezolute, Inc.$23M9.50%2.69%-19.2%Q4 2024
NKTRNektar Therapeutics$17.1M7.04%1.53%Not reportedQ3 2019
ZURAZura Bio Ltd$16.5M6.81%5.87%+20.4%Q2 2023
SLNOSoleno Therapeutics Inc$15.2M6.27%0.42%NewQ3 2025
ASNDAscendis Pharma A/S$14.9M6.15%0.12%Not reportedQ1 2015
ABVXAbivax S.A.$12.7M5.25%0.24%-88.4%Q4 2023
APGEApogee Therapeutics, Inc.$12.1M4.98%0.51%Not reportedQ3 2023
DNTHDianthus Therapeutics, Inc.$10.5M4.31%0.62%Not reportedQ1 2024
CYTKCytokinetics Inc$8.24M3.40%0.13%Not reportedQ1 2014
IMVTImmunovant, Inc.$8.06M3.32%0.29%+90.7%Q1 2025
XENEXenon Pharmaceuticals Inc.$8.03M3.31%0.26%Not reportedQ3 2021
NGNENeurogene Inc.$7.74M3.19%3.02%-8.0%Q4 2023
EPRXEupraxia Pharmaceuticals Inc.$7.08M2.92%3.37%NewQ3 2025
UPBUpstream Bio, Inc.$5.64M2.33%0.56%Not reportedQ4 2024
JBIOJade Biosciences, Inc.$5.46M2.25%1.94%+27.0%Q2 2025
IONSIonis Pharmaceuticals Inc$5.23M2.16%0.05%-84.0%Q3 2019
AKROAkero Therapeutics, Inc.$4.93M2.03%0.13%Not reportedQ3 2023
TSHATaysha Gene Therapies, Inc.$4.91M2.02%0.55%Not reportedQ2 2025
CNTXContext Therapeutics Inc.$4.54M1.87%5.10%Not reportedQ2 2024
PHVSPharvaris N.V.$3.87M1.60%0.29%NewQ3 2025
DBVTDBV Technologies S.A.$3.79M1.56%0.28%+1.0%Q3 2016
LEGNLegend Biotech Corp$3.7M1.53%0.03%-67.6%Q1 2025
ORKAOruka Therapeutics, Inc.$3.53M1.45%0.38%Not reportedQ3 2024
UNCYUnicycive Therapeutics, Inc.$3.47M1.43%3.82%Not reportedQ3 2024
SANASana Biotechnology, Inc.$2.49M1.02%0.27%NewQ3 2025
ABSIAbsci Corp$2.42M1.00%0.53%NewQ3 2025
PLRXPliant Therapeutics, Inc.$1.26M0.52%1.38%Not reportedQ2 2022
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