Sphera Funds Management Ltd.
Net buyer this quarter
$767M
95
+$18.6M
33.3%
Holdings
| Company | Value | % of portfolio | % of company | POSITION CHANGE qoq % | First reported |
|---|---|---|---|---|---|
| Q2 2026 | |||||
 TEVA | $50.8M | 6.63% | 0.13% | +31.9% | Q4 2013 |
 MLYS | $39.7M | 5.17% | 1.66% | +9.7% | Q1 2023 |
 TSEM | $28.2M | 3.68% | 0.10% | -25.7% | Q1 2016 |
 SNDX | $22.2M | 2.89% | 1.14% | +40.0% | Q3 2016 |
 BIIB | $20.9M | 2.72% | 0.07% | +4.4% | Q4 2013 |
 RARE | $19.6M | 2.56% | 0.60% | -27.3% | Q2 2015 |
 BMRN | $18.8M | 2.45% | 0.17% | +134.9% | Q2 2014 |
 CYTK | $18.7M | 2.44% | 0.18% | +452.5% | Q4 2013 |
 BBIO | $18.3M | 2.38% | 0.13% | 0.0% | Q4 2020 |
 COGT | $17.8M | 2.32% | 0.27% | +10.3% | Q4 2020 |
 NVMI | $13.7M | 1.78% | 0.08% | -52.8% | Q1 2014 |
 INSM | $12.7M | 1.65% | 0.05% | Not reported | Q4 2013 |
 MAZE | $12.5M | 1.63% | 0.75% | +83.7% | Q1 2025 |
 AZN | $11.9M | 1.55% | Not reported | Not reported | Q3 2014 |
 SNY | $11.5M | 1.50% | 0.02% | Not reported | Q1 2014 |
 HELP | $10.7M | 1.40% | 3.14% | +64.2% | Q3 2024 |
 LLY | $9.64M | 1.26% | 0.00% | -11.1% | Q1 2014 |
 MDGL | $9.35M | 1.22% | 0.08% | +92.7% | Q1 2023 |
 TRVI | $9.31M | 1.21% | 0.35% | -13.1% | Q2 2025 |
 ACAD | $9.02M | 1.18% | 0.21% | +39.2% | Q4 2013 |
 CLDX | $8.96M | 1.17% | 0.31% | -1.1% | Q1 2015 |
 RYTM | $8.93M | 1.16% | 0.12% | New | Q2 2026 |
 ORIC | $8.15M | 1.06% | 0.73% | +40.1% | Q4 2020 |
 LRCX | $8M | 1.04% | 0.00% | Not reported | Q4 2017 |
 AMAT | $7.98M | 1.04% | 0.00% | Not reported | Q3 2021 |
 TNGX | $7.95M | 1.04% | 0.15% | -26.0% | Q3 2024 |
 NVS | $7.83M | 1.02% | 0.00% | +35.1% | Q4 2013 |
 VOR | $7.67M | 1.00% | 0.76% | +29.4% | Q4 2025 |
 ABBV | $7.61M | 0.99% | 0.00% | Not reported | Q3 2014 |
 MRK | $7.53M | 0.98% | 0.00% | +20.6% | Q4 2013 |
 JNJ | $7.32M | 0.96% | 0.00% | Not reported | Q4 2013 |
 IDYA | $7.32M | 0.95% | 0.20% | Not reported | Q1 2021 |
 IMTX | $7.29M | 0.95% | 0.54% | +3.4% | Q3 2020 |
 NVCT | $7.04M | 0.92% | 1.43% | New | Q2 2026 |
 PFE | $6.89M | 0.90% | 0.01% | +53.8% | Q4 2013 |
 HRMY | $6.43M | 0.84% | 0.30% | New | Q2 2026 |
 XENE | $6.34M | 0.83% | 0.11% | -17.3% | Q3 2016 |
 CLYM | $6.31M | 0.82% | 0.84% | +15.4% | Q2 2024 |
 ZBIO | $5.86M | 0.76% | 0.36% | +7.7% | Q1 2026 |
 NVO | $5.79M | 0.75% | Not reported | Not reported | Q1 2019 |
 ELVN | $5.72M | 0.75% | 0.15% | -26.4% | Q1 2025 |
 PRLD | $5.44M | 0.71% | 1.28% | +82.7% | Q4 2025 |
 GSK | $5.35M | 0.70% | 0.00% | -16.4% | Q4 2013 |
| FBRX | $5.31M | 0.69% | 1.22% | +35.0% | Q2 2025 |
 BIOA | $5.24M | 0.68% | 0.47% | +147.0% | Q4 2025 |
 SRRK | $5.18M | 0.68% | 0.08% | Not reported | Q2 2018 |
 MSLE | $5.07M | 0.66% | 50.66% | +33.4% | Q1 2026 |
 PALI | $4.72M | 0.62% | 1.30% | +30.2% | Q4 2025 |
 ELDN | $4.69M | 0.61% | 1.47% | -32.8% | Q2 2024 |
 VST | $4.67M | 0.61% | 0.01% | New | Q2 2026 |
| Q1 2026 | |||||
| MLYS | $36.3M | 5.76% | 1.63% | +198.4% | Q1 2023 |
| TEVA | $34.2M | 5.44% | 0.10% | +1.2% | Q4 2013 |
| TSEM | $25.6M | 4.06% | 0.13% | +19.0% | Q1 2016 |
| NVMI | $23.2M | 3.68% | 0.17% | +11.5% | Q1 2014 |
| BBIO | $18.2M | 2.89% | 0.13% | +127.6% | Q4 2020 |
| BIIB | $17M | 2.69% | 0.06% | -2.3% | Q4 2013 |
| RARE | $17M | 2.69% | 0.82% | +169.2% | Q2 2015 |
| SNDX | $16.9M | 2.69% | 0.82% | -5.0% | Q3 2016 |
| COGT | $16M | 2.54% | 0.24% | +10.0% | Q4 2020 |
| SNY | $13M | 2.06% | 0.02% | +12.5% | Q1 2014 |
| AZN | $12.3M | 1.96% | Not reported | -7.4% | Q3 2014 |
| FOLD | $8.72M | 1.39% | 0.19% | -8.4% | Q1 2015 |
 CLBT | $8.7M | 1.38% | 0.25% | Not reported | Q3 2025 |
| APLS | $8.65M | 1.37% | 0.17% | -14.4% | Q2 2018 |
 PANW | $8.46M | 1.34% | 0.01% | Not reported | Q3 2015 |
| LLY | $8.31M | 1.32% | 0.00% | Not reported | Q1 2014 |
 BCRX | $8.25M | 1.31% | 0.34% | +3.4% | Q4 2025 |
 CAMT | $8.04M | 1.28% | 0.12% | +34.2% | Q1 2019 |
| BMRN | $7.9M | 1.26% | 0.07% | -4.8% | Q2 2014 |
| CLDX | $7.73M | 1.23% | 0.37% | +1.6% | Q1 2015 |
 ORA | $7.64M | 1.21% | 0.11% | Not reported | Q1 2014 |
| XENE | $7.39M | 1.17% | 0.13% | Not reported | Q3 2016 |
| SLNO | $7.24M | 1.15% | 0.42% | +58.7% | Q2 2020 |
| TNGX | $7.19M | 1.14% | 0.24% | -36.9% | Q3 2024 |
| JNJ | $7.05M | 1.12% | 0.00% | -19.5% | Q4 2013 |
| IMTX | $6.85M | 1.09% | 0.52% | -19.2% | Q3 2020 |
| TRVI | $6.85M | 1.09% | 0.45% | -4.1% | Q2 2025 |
| ORIC | $6.81M | 1.08% | 0.52% | -46.5% | Q4 2020 |
| MAZE | $6.79M | 1.08% | 0.46% | +216.4% | Q1 2025 |
| GSK | $6.73M | 1.07% | 0.00% | Not reported | Q4 2013 |
 AMZN | $6.65M | 1.06% | 0.00% | Not reported | Q1 2019 |
| ABBV | $6.58M | 1.05% | 0.00% | +19.8% | Q3 2014 |
 AAOI | $6.21M | 0.99% | 0.09% | New | Q1 2026 |
| ELVN | $6.01M | 0.95% | 0.25% | -32.4% | Q1 2025 |
| MRK | $5.85M | 0.93% | 0.00% | Not reported | Q4 2013 |
| VOR | $5.74M | 0.91% | 0.59% | -21.6% | Q4 2025 |
| ACAD | $5.7M | 0.91% | 0.15% | +20.7% | Q4 2013 |
| NVS | $5.65M | 0.90% | 0.00% | Not reported | Q4 2013 |
| ELDN | $5.46M | 0.87% | 2.34% | -16.9% | Q2 2024 |
 ENPH | $5.38M | 0.86% | 0.11% | -23.6% | Q2 2020 |
 RVMD | $5.36M | 0.85% | 0.03% | +5.0% | Q3 2025 |
| PFE | $5.22M | 0.83% | 0.00% | +116.3% | Q4 2013 |
 BHVN | $5.03M | 0.80% | 0.39% | Not reported | Q1 2018 |
| FBRX | $4.79M | 0.76% | 1.33% | -0.5% | Q2 2025 |
| HELP | $4.74M | 0.75% | 1.91% | +19.6% | Q3 2024 |
| MDGL | $4.73M | 0.75% | 0.04% | +173.9% | Q1 2023 |
| SRRK | $4.63M | 0.74% | 0.08% | -40.4% | Q2 2018 |
| NVO | $4.43M | 0.70% | Not reported | +4.3% | Q1 2019 |
 MDWD | $4.4M | 0.70% | 2.13% | +18.6% | Q3 2022 |
 KOD | $4.38M | 0.69% | 0.18% | -34.6% | Q4 2025 |
| Q4 2025 | |||||
| TEVA | $35.1M | 6.78% | 0.10% | -25.5% | Q4 2013 |
| BIIB | $16.7M | 3.22% | 0.06% | +14.5% | Q4 2013 |
| MLYS | $16.3M | 3.15% | 0.55% | +104.2% | Q1 2023 |
| SNDX | $16M | 3.10% | 0.87% | +96.7% | Q3 2016 |
| NVMI | $15.7M | 3.04% | 0.15% | +9.0% | Q1 2014 |
| TSEM | $14.4M | 2.78% | 0.11% | -60.7% | Q1 2016 |
| COGT | $13.4M | 2.60% | 0.24% | +284.2% | Q4 2020 |
| AZN | $12.4M | 2.40% | Not reported | Not reported | Q3 2014 |
| SNY | $11.6M | 2.24% | 0.02% | +9.1% | Q1 2014 |
| LLY | $9.72M | 1.88% | 0.00% | -10.0% | Q1 2014 |
| FOLD | $9.38M | 1.81% | 0.21% | -33.6% | Q1 2015 |
| IMTX | $9.04M | 1.75% | 0.64% | +47.7% | Q3 2020 |
| BMRN | $8.74M | 1.69% | 0.08% | Not reported | Q2 2014 |
| BBIO | $8.24M | 1.59% | 0.06% | +164.4% | Q4 2020 |
| ORIC | $8.22M | 1.59% | 1.02% | +132.7% | Q4 2020 |
 DYN | $7.69M | 1.49% | 0.24% | -7.9% | Q3 2020 |
| TRVI | $7.49M | 1.45% | 0.47% | -7.1% | Q2 2025 |
| JNJ | $7.42M | 1.43% | 0.00% | -12.3% | Q4 2013 |
 SVRA | $7.1M | 1.37% | 0.58% | -12.8% | Q3 2017 |
| SRRK | $6.97M | 1.35% | 0.15% | Not reported | Q2 2018 |
 WVE | $6.94M | 1.34% | 0.22% | +716.3% | Q2 2019 |
| RARE | $6.91M | 1.34% | 0.31% | -14.7% | Q2 2015 |
| HELP | $6.75M | 1.31% | 3.82% | +122.9% | Q3 2024 |
 ANNX | $6.61M | 1.28% | 0.88% | -26.7% | Q3 2021 |
| BCRX | $6.54M | 1.26% | 0.39% | New | Q4 2025 |
| CLDX | $6.51M | 1.26% | 0.36% | +15.4% | Q1 2015 |
| SLNO | $6.31M | 1.22% | 0.26% | +227.6% | Q2 2020 |
| APLS | $6.3M | 1.22% | 0.20% | +294.2% | Q2 2018 |
| GSK | $5.98M | 1.16% | 0.00% | Not reported | Q4 2013 |
| ENPH | $5.98M | 1.16% | 0.14% | +598.5% | Q2 2020 |
| NVO | $5.89M | 1.14% | Not reported | +9.5% | Q1 2019 |
| CYTK | $5.83M | 1.13% | 0.07% | -43.2% | Q4 2013 |
| ABBV | $5.77M | 1.12% | 0.00% | Not reported | Q3 2014 |
 SEDG | $5.67M | 1.10% | 0.33% | +39.4% | Q4 2016 |
| ACAD | $5.67M | 1.10% | 0.12% | +42.5% | Q4 2013 |
| VOR | $5.37M | 1.04% | 1.06% | New | Q4 2025 |
| MRK | $5.12M | 0.99% | 0.00% | Not reported | Q4 2013 |
| NVS | $5.1M | 0.99% | 0.00% | Not reported | Q4 2013 |
| FBRX | $5.07M | 0.98% | 1.44% | -60.8% | Q2 2025 |
| KOD | $4.91M | 0.95% | 0.28% | New | Q4 2025 |
| TNGX | $4.82M | 0.93% | 0.40% | Not reported | Q3 2024 |
| ATXS | $4.66M | 0.90% | 0.62% | +41.6% | Q4 2022 |
| MDWD | $4.25M | 0.82% | 1.79% | +24.3% | Q3 2022 |
| CAMT | $4.2M | 0.81% | 0.09% | +36.0% | Q1 2019 |
| RVMD | $4.18M | 0.81% | 0.03% | -12.5% | Q3 2025 |
 AMD | $3.86M | 0.75% | 0.00% | +16.6% | Q1 2022 |
| CLYM | $3.73M | 0.72% | 1.95% | +114.4% | Q2 2024 |
 ACOG | $3.69M | 0.71% | 2.61% | +67.6% | Q4 2024 |
| ELVN | $3.49M | 0.68% | 0.38% | +36.0% | Q1 2025 |
 TARA | $3.46M | 0.67% | 1.21% | New | Q4 2025 |
| Q3 2025 | |||||
| TEVA | $30.4M | 6.42% | 0.13% | -7.0% | Q4 2013 |
 NICE | $22.8M | 4.81% | 0.25% | Not reported | Q3 2014 |
| TSEM | $22.5M | 4.76% | 0.28% | +17.8% | Q1 2016 |
| NVMI | $14M | 2.96% | 0.15% | -42.1% | Q1 2014 |
 QQQ | $13.8M | 2.91% | Not reported | Not reported | Q2 2022 |
| BIIB | $11.6M | 2.44% | 0.06% | Not reported | Q4 2013 |
| RARE | $10.6M | 2.24% | 0.37% | +252.3% | Q2 2015 |
| AZN | $10.4M | 2.19% | Not reported | Not reported | Q3 2014 |
| SNY | $10.4M | 2.19% | 0.02% | Not reported | Q1 2014 |
| CYTK | $8.88M | 1.87% | 0.14% | -50.6% | Q4 2013 |
| MLYS | $8.34M | 1.76% | 0.28% | -54.3% | Q1 2023 |
| FOLD | $7.81M | 1.65% | 0.32% | 0.0% | Q1 2015 |
| LLY | $7.66M | 1.62% | 0.00% | -13.0% | Q1 2014 |
| JNJ | $7.57M | 1.60% | 0.00% | Not reported | Q4 2013 |
| CDTX | $7.25M | 1.53% | 0.26% | -45.1% | Q4 2017 |
| FBRX | $7.11M | 1.50% | 3.79% | -4.2% | Q2 2025 |
| SNDX | $5.97M | 1.26% | 0.45% | -75.3% | Q3 2016 |
| TRVI | $5.89M | 1.24% | 0.50% | -19.5% | Q2 2025 |
| NVO | $5.86M | 1.24% | Not reported | Not reported | Q1 2019 |
| ABBV | $5.85M | 1.23% | 0.00% | Not reported | Q3 2014 |
| CLBT | $5.54M | 1.17% | 0.12% | New | Q3 2025 |
| ANNX | $5.47M | 1.15% | 1.64% | +1.7% | Q3 2021 |
| DYN | $5.4M | 1.14% | 0.30% | +92.6% | Q3 2020 |
| CLDX | $5.37M | 1.13% | 0.31% | -50.5% | Q1 2015 |
| GSK | $5.27M | 1.11% | 0.00% | Not reported | Q4 2013 |
| SEDG | $5.22M | 1.10% | 0.24% | +10.2% | Q4 2016 |
| ORIC | $5.18M | 1.09% | 0.44% | +9.4% | Q4 2020 |
| IMTX | $4.97M | 1.05% | 0.48% | Not reported | Q3 2020 |
 GPCR | $4.87M | 1.03% | 0.10% | +81.3% | Q1 2025 |
| SVRA | $4.82M | 1.02% | 0.78% | +3.1% | Q3 2017 |
| NVS | $4.74M | 1.00% | 0.00% | Not reported | Q4 2013 |
 RAPP | $4.68M | 0.99% | 0.33% | New | Q3 2025 |
 VRNS | $4.25M | 0.90% | 0.06% | Not reported | Q3 2020 |
 IMVT | $4.14M | 0.87% | 0.15% | Not reported | Q4 2019 |
| MRK | $4.08M | 0.86% | 0.00% | Not reported | Q4 2013 |
| MAZE | $4M | 0.84% | 0.32% | -56.7% | Q1 2025 |
 ENGN | $3.45M | 0.73% | 0.99% | Not reported | Q4 2024 |
 ESLT | $3.44M | 0.72% | 0.02% | +12.3% | Q3 2014 |
 RZLT | $3.42M | 0.72% | 0.40% | -51.6% | Q2 2022 |
| ELVN | $3.41M | 0.72% | 0.28% | +29.8% | Q1 2025 |
| MDWD | $3.34M | 0.70% | 1.72% | Not reported | Q3 2022 |
| ELDN | $3.32M | 0.70% | 2.14% | -34.7% | Q2 2024 |
| ACAD | $3.18M | 0.67% | 0.09% | -14.9% | Q4 2013 |
 PRAX | $3.07M | 0.65% | 0.27% | -47.3% | Q4 2020 |
| CAMT | $3.05M | 0.64% | 0.06% | -9.2% | Q1 2019 |
| AMZN | $3.02M | 0.64% | 0.00% | -57.6% | Q1 2019 |
 CRVS | $3M | 0.63% | 0.55% | +122.7% | Q1 2016 |
 PHVS | $2.98M | 0.63% | 0.22% | -61.5% | Q4 2023 |
 META | $2.88M | 0.61% | Not reported | -54.0% | Q4 2016 |
| SLNO | $2.81M | 0.59% | 0.08% | Not reported | Q2 2020 |