Skip to main content

Casdin Capital, LLC

13F filer · CIK 0001534261
Reported Aug 14, 2026
Net buyer this quarter
13F portfolio value$2BU.S. long equity reported on 13F
Positions436 new · 3 closed
Net flow last quarter+$55.5MBuys minus sells
Top 10 positions weight77.4%Concentration

Holdings

13F · last 4 quarters free
Scroll for earlier quarters
CompanyValue% of portfolio% of companyPOSITION CHANGE qoq %First reported
Q2 2026Reported Aug 14, 202643 positions
RVMDRevolution Medicines, Inc.$483M24.16%1.20%Not reportedQ1 2020
RLAYRelay Therapeutics, Inc.$300M15.02%7.34%+11.2%Q3 2020
WGSGeneDx Holdings Corp.$254M12.74%12.44%+23.3%Q3 2021
BLFSBiolife Solutions Inc$131M6.58%9.52%-21.9%Q2 2018
ILMNIllumina, Inc.$93.2M4.66%0.35%Not reportedQ4 2015
LABStandard Biotools Inc.$73M3.66%22.64%Not reportedQ2 2023
GPCRStructure Therapeutics Inc.$63.1M3.16%0.55%Not reportedQ1 2023
DNLIDenali Therapeutics Inc.$52.6M2.63%1.28%+11.1%Q4 2018
NGNENeurogene Inc.$48.6M2.43%9.76%+8.8%Q4 2023
BEAMBeam Therapeutics Inc.$46.3M2.32%1.31%Not reportedQ4 2020
TXG10x Genomics, Inc.$40.3M2.02%0.82%-53.9%Q4 2025
SRRKScholar Rock Holding Corp$36.6M1.83%0.55%+90.0%Q4 2025
PSNLPersonalis, Inc.$34.2M1.71%2.40%+59.4%Q1 2026
GRALGRAIL, Inc.$32.8M1.64%1.07%+108.7%Q2 2024
GHGuardant Health, Inc.$27.8M1.39%0.14%-41.3%Q4 2021
MAZEMaze Therapeutics, Inc.$25.2M1.26%1.52%+11.2%Q1 2025
HIMSHims & Hers Health, Inc.$24.3M1.21%Not reportedNot reportedQ1 2025
ALNYAlnylam Pharmaceuticals, Inc.$22.6M1.13%0.06%Not reportedQ4 2015
TSHATaysha Gene Therapies, Inc.$22.1M1.11%1.00%Not reportedQ3 2020
AGMBAgomab Therapeutics NV$20.1M1.01%4.54%Not reportedQ1 2026
SEPNSepterna, Inc.$18.5M0.93%1.21%Not reportedQ4 2024
PBLSParabilis Medicines, Inc.$17.7M0.88%0.53%NewQ2 2026
SIONSionna Therapeutics, Inc.$17.6M0.88%0.89%NewQ2 2026
VCYTVeracyte, Inc.$16.2M0.81%0.34%Not reportedQ1 2024
ANLAdlai Nortye Ltd.$14.4M0.72%Not reported+132.1%Q1 2026
PRMEPrime Medicine, Inc.$11.7M0.58%1.75%Not reportedQ4 2022
ABSIAbsci Corp$11.3M0.56%0.62%Not reportedQ3 2021
DGXQuest Diagnostics Inc$10.6M0.53%0.05%Not reportedQ4 2025
SRPTSarepta Therapeutics, Inc.$8.45M0.42%0.45%Not reportedQ3 2018
QUREuniQure N.V.$6.91M0.35%0.22%NewQ2 2026
NTLAIntellia Therapeutics, Inc.$6.01M0.30%0.25%Not reportedQ3 2022
MRNAModerna, Inc.$5.25M0.26%0.02%Not reportedQ3 2022
IRONDisc Medicine, Inc.$4.75M0.24%0.17%Not reportedQ1 2026
GLUEMonte Rosa Therapeutics, Inc.$4.5M0.23%0.22%Not reportedQ2 2021
IPSCCentury Therapeutics, Inc.$3.01M0.15%0.68%Not reportedQ2 2021
CTNMContineum Therapeutics, Inc.$2.43M0.12%0.64%Not reportedQ2 2024
BBOTBridgeBio Oncology Therapeutics, Inc.$2.15M0.11%0.35%Not reportedQ3 2025
EDITEditas Medicine, Inc.$1.44M0.07%0.45%Not reportedQ1 2016
PACBPacific Biosciences of California, Inc.$1.22M0.06%0.23%Not reportedQ1 2017
KARDKardigan, Inc.$1.19M0.06%0.05%NewQ2 2026
RXRXRecursion Pharmaceuticals, Inc.$607K0.03%0.03%Not reportedQ2 2021
DNAGinkgo Bioworks Holdings, Inc.$362K0.02%0.06%Not reportedQ3 2021
TNYATenaya Therapeutics, Inc.$268K0.01%0.16%Not reportedQ3 2021
Q1 2026Reported May 15, 202640 positions
RVMDRevolution Medicines, Inc.$251M18.98%1.29%Not reportedQ1 2020
WGSGeneDx Holdings Corp.$193M14.62%10.14%Not reportedQ3 2021
RLAYRelay Therapeutics, Inc.$143M10.86%7.62%+10.9%Q3 2020
BLFSBiolife Solutions Inc$114M8.61%12.20%Not reportedQ2 2018
LABStandard Biotools Inc.$81.6M6.18%22.76%Not reportedQ2 2023
ILMNIllumina, Inc.$65.3M4.95%0.35%-11.7%Q4 2015
GPCRStructure Therapeutics Inc.$56.6M4.29%0.55%Not reportedQ1 2023
TXG10x Genomics, Inc.$48.3M3.66%1.78%+62.5%Q4 2025
DNLIDenali Therapeutics Inc.$35.3M2.68%1.16%Not reportedQ4 2018
BEAMBeam Therapeutics Inc.$32.2M2.44%1.31%-15.6%Q4 2020
GHGuardant Health, Inc.$29.1M2.20%0.24%-17.1%Q4 2021
NGNENeurogene Inc.$28.6M2.17%9.10%+9.7%Q4 2023
ALNYAlnylam Pharmaceuticals, Inc.$24.8M1.88%0.06%Not reportedQ4 2015
MAZEMaze Therapeutics, Inc.$22.7M1.72%1.53%Not reportedQ1 2025
SRRKScholar Rock Holding Corp$17.2M1.30%0.29%+34.6%Q4 2025
AGMBAgomab Therapeutics NV$16.3M1.23%4.54%NewQ1 2026
HIMSHims & Hers Health, Inc.$14.5M1.10%Not reported+81.8%Q1 2025
TSHATaysha Gene Therapies, Inc.$14.5M1.10%1.13%+116.7%Q3 2020
QGENQiagen N.V.$14.4M1.09%0.17%NewQ1 2026
TEMTempus AI, Inc.$13.3M1.01%Not reportedNot reportedQ3 2025
SEPNSepterna, Inc.$13.3M1.01%1.23%Not reportedQ4 2024
GRALGRAIL, Inc.$11.9M0.90%0.56%Not reportedQ2 2024
PRMEPrime Medicine, Inc.$11M0.83%1.75%Not reportedQ4 2022
PSNLPersonalis, Inc.$10.2M0.77%1.53%NewQ1 2026
DGXQuest Diagnostics Inc$9.8M0.74%0.05%Not reportedQ4 2025
VCYTVeracyte, Inc.$8.9M0.67%0.35%Not reportedQ1 2024
MLTXMoonLake Immunotherapeutics$8.39M0.64%0.85%NewQ1 2026
NTLAIntellia Therapeutics, Inc.$4.55M0.34%0.29%Not reportedQ3 2022
IRONDisc Medicine, Inc.$4.16M0.31%0.17%NewQ1 2026
MRNAModerna, Inc.$3.81M0.29%0.02%Not reportedQ3 2022
ANLAdlai Nortye Ltd.$3.73M0.28%Not reportedNewQ1 2026
GLUEMonte Rosa Therapeutics, Inc.$3.06M0.23%0.22%+116.3%Q2 2021
ABSIAbsci Corp$2.92M0.22%0.64%Not reportedQ3 2021
IPSCCentury Therapeutics, Inc.$2.78M0.21%0.68%Not reportedQ2 2021
BBOTBridgeBio Oncology Therapeutics, Inc.$2.53M0.19%0.35%Not reportedQ3 2025
CTNMContineum Therapeutics, Inc.$1.94M0.15%0.64%Not reportedQ2 2024
PACBPacific Biosciences of California, Inc.$955K0.07%0.23%-82.9%Q1 2017
RXRXRecursion Pharmaceuticals, Inc.$508K0.04%0.03%Not reportedQ2 2021
TNYATenaya Therapeutics, Inc.$251K0.02%0.17%Not reportedQ3 2021
DNAGinkgo Bioworks Holdings, Inc.$224K0.02%0.06%Not reportedQ3 2021
Q4 2025Reported Feb 17, 202638 positions
WGSGeneDx Holdings Corp.$391M24.29%10.28%Not reportedQ3 2021
RVMDRevolution Medicines, Inc.$205M12.75%1.31%-2.6%Q1 2020
BLFSBiolife Solutions Inc$144M8.95%12.36%-11.2%Q2 2018
LABStandard Biotools Inc.$114M7.06%22.98%+14.5%Q2 2023
RLAYRelay Therapeutics, Inc.$110M6.83%7.48%+14.7%Q3 2020
GPCRStructure Therapeutics Inc.$81.7M5.08%0.55%-24.4%Q1 2023
ILMNIllumina, Inc.$78.7M4.89%0.39%+14.3%Q4 2015
RNAMAvidity Biosciences, Inc.$72.1M4.48%0.66%-43.8%Q4 2022
BEAMBeam Therapeutics Inc.$44.4M2.75%1.57%Not reportedQ4 2020
GHGuardant Health, Inc.$38.8M2.41%0.29%+280.0%Q4 2021
MAZEMaze Therapeutics, Inc.$31.4M1.95%1.54%Not reportedQ1 2025
DNLIDenali Therapeutics Inc.$30.4M1.89%1.18%+106.7%Q4 2018
ALNYAlnylam Pharmaceuticals, Inc.$29.8M1.85%0.06%+36.4%Q4 2015
NGNENeurogene Inc.$26.7M1.66%8.36%Not reportedQ4 2023
TXG10x Genomics, Inc.$22.8M1.42%1.10%NewQ4 2025
SPRYARS Pharmaceuticals, Inc.$18.6M1.16%1.61%Not reportedQ3 2025
TEMTempus AI, Inc.$17.4M1.08%Not reportedNot reportedQ3 2025
UNHUnitedhealth Group Inc$16.5M1.03%0.01%+100.0%Q3 2025
SEPNSepterna, Inc.$15.4M0.96%1.23%Not reportedQ4 2024
HIMSHims & Hers Health, Inc.$12.5M0.78%Not reported+67.4%Q1 2025
VCYTVeracyte, Inc.$11.6M0.72%0.35%Not reportedQ1 2024
DXCMDexcom Inc$11.6M0.72%0.05%Not reportedQ4 2015
SRRKScholar Rock Holding Corp$11.5M0.71%0.24%NewQ4 2025
CICigna Group$11M0.68%0.02%NewQ4 2025
PRMEPrime Medicine, Inc.$11M0.68%1.75%Not reportedQ4 2022
INCYIncyte Corp$9.88M0.61%0.05%Not reportedQ4 2022
DGXQuest Diagnostics Inc$8.68M0.54%0.04%NewQ4 2025
TSHATaysha Gene Therapies, Inc.$8.25M0.51%0.53%Not reportedQ3 2020
PACBPacific Biosciences of California, Inc.$7.9M0.49%1.40%+483.6%Q1 2017
LEGNLegend Biotech Corp$4.67M0.29%0.06%Not reportedQ2 2020
BBOTBridgeBio Oncology Therapeutics, Inc.$3.53M0.22%0.35%Not reportedQ3 2025
ABSIAbsci Corp$3.4M0.21%0.65%Not reportedQ3 2021
CTNMContineum Therapeutics, Inc.$1.7M0.11%0.64%Not reportedQ2 2024
GLUEMonte Rosa Therapeutics, Inc.$1.35M0.08%0.13%Not reportedQ2 2021
IPSCCentury Therapeutics, Inc.$1.22M0.08%1.40%Not reportedQ2 2021
RXRXRecursion Pharmaceuticals, Inc.$676K0.04%0.03%Not reportedQ2 2021
DNAGinkgo Bioworks Holdings, Inc.$303K0.02%0.06%Not reportedQ3 2021
TNYATenaya Therapeutics, Inc.$258K0.02%0.17%Not reportedQ3 2021
Q3 2025Reported Nov 14, 202532 positions
WGSGeneDx Holdings Corp.$324M27.01%10.41%-14.3%Q3 2021
BLFSBiolife Solutions Inc$171M14.27%13.98%-13.0%Q2 2018
RVMDRevolution Medicines, Inc.$124M10.31%1.40%-8.3%Q1 2020
LABStandard Biotools Inc.$101M8.41%20.22%+2.0%Q2 2023
RNAMAvidity Biosciences, Inc.$77.6M6.47%1.21%+0.3%Q4 2022
RLAYRelay Therapeutics, Inc.$59.2M4.94%6.57%-0.5%Q3 2020
ILMNIllumina, Inc.$49.9M4.16%0.34%-18.6%Q4 2015
GPCRStructure Therapeutics Inc.$43.5M3.63%0.85%+26.9%Q1 2023
BEAMBeam Therapeutics Inc.$38.8M3.24%1.58%+10.3%Q4 2020
ALNYAlnylam Pharmaceuticals, Inc.$25.1M2.09%0.04%-32.5%Q4 2015
TEMTempus AI, Inc.$23.7M1.98%Not reportedNewQ3 2025
NGNENeurogene Inc.$22.4M1.87%8.77%Not reportedQ4 2023
MAZEMaze Therapeutics, Inc.$19.7M1.64%1.58%Not reportedQ1 2025
PRMEPrime Medicine, Inc.$17.5M1.46%1.76%+102.1%Q4 2022
SPRYARS Pharmaceuticals, Inc.$16.1M1.34%1.62%NewQ3 2025
HIMSHims & Hers Health, Inc.$13M1.09%Not reportedNot reportedQ1 2025
DNLIDenali Therapeutics Inc.$12.9M1.08%0.61%Not reportedQ4 2018
SEPNSepterna, Inc.$10.4M0.87%1.24%Not reportedQ4 2024
VCYTVeracyte, Inc.$9.49M0.79%0.35%Not reportedQ1 2024
UNHUnitedhealth Group Inc$8.63M0.72%0.00%NewQ3 2025
INCYIncyte Corp$8.48M0.71%0.05%Not reportedQ4 2022
GHGuardant Health, Inc.$6.25M0.52%0.08%Not reportedQ4 2021
EXKEndeavour Silver Corp$4.92M0.41%0.03%Not reportedQ1 2016
BBOTBridgeBio Oncology Therapeutics, Inc.$3.27M0.27%0.36%NewQ3 2025
ABSIAbsci Corp$2.96M0.25%0.65%Not reportedQ3 2021
CTNMContineum Therapeutics, Inc.$1.74M0.15%0.53%Not reportedQ2 2024
PACBPacific Biosciences of California, Inc.$926K0.08%0.24%Not reportedQ1 2017
RXRXRecursion Pharmaceuticals, Inc.$807K0.07%0.03%Not reportedQ2 2021
GLUEMonte Rosa Therapeutics, Inc.$637K0.05%0.14%Not reportedQ2 2021
IPSCCentury Therapeutics, Inc.$612K0.05%1.42%Not reportedQ2 2021
TNYATenaya Therapeutics, Inc.$586K0.05%0.22%Not reportedQ3 2021
DNAGinkgo Bioworks Holdings, Inc.$532K0.04%0.06%Not reportedQ3 2021
Premium opens every quarter this fund has filed

Not investment advice. We make every effort to keep the information on SpoorBase accurate, but errors may occur. SpoorBase does not guarantee the accuracy or completeness of any data, and any use of the information is at the user’s sole responsibility. Valuation multiples are calculated by SpoorBase and may contain errors. See Disclosures. © 2026 SpoorBase. All rights reserved.