Samsara Biocapital, LLC
Net buyer this quarter
$1.22B
24
+$79.7M
90.5%
Holdings
| Company | Value | % of portfolio | % of company | POSITION CHANGE qoq % | First reported |
|---|---|---|---|---|---|
| Q2 2026 | |||||
 SRRK | $379M | 31.16% | 5.67% | Not reported | Q1 2022 |
 ALMS | $179M | 14.67% | Not reported | Not reported | Q3 2024 |
 MLYS | $158M | 13.01% | 6.65% | Not reported | Q1 2023 |
 SEPN | $105M | 8.66% | 6.90% | Not reported | Q4 2024 |
 ALMR | $67.2M | 5.52% | 3.58% | New | Q2 2026 |
 NGNE | $54M | 4.44% | 10.85% | Not reported | Q4 2023 |
 KLRS | $52.4M | 4.31% | 54.11% | -0.5% | Q1 2025 |
 SGP | $47M | 3.86% | 6.31% | Not reported | Q1 2026 |
 STRO | $35.3M | 2.90% | 6.41% | Not reported | Q4 2018 |
 IVA | $23.9M | 1.96% | 3.27% | +21.6% | Q4 2025 |
 JBIO | $16.4M | 1.34% | 1.16% | -24.0% | Q2 2025 |
 PBLS | $15.2M | 1.25% | 0.46% | New | Q2 2026 |
 VTVT | $11.2M | 0.92% | Not reported | Not reported | Q4 2021 |
 AQST | $10.4M | 0.85% | 1.99% | Not reported | Q3 2025 |
 NKTX | $9.93M | 0.82% | 4.90% | Not reported | Q3 2020 |
 ARTV | $9.26M | 0.76% | 3.86% | Not reported | Q3 2024 |
 RANI | $7.88M | 0.65% | Not reported | +22.0% | Q4 2025 |
 AGMB | $7.79M | 0.64% | 1.76% | Not reported | Q1 2026 |
 ABVX | $7.34M | 0.60% | 0.07% | -2.6% | Q4 2023 |
 XFOR | $6.52M | 0.54% | 1.45% | -23.9% | Q4 2025 |
 ELOX | $5.55M | 0.46% | 9.91% | New | Q2 2026 |
 CHRS | $4.8M | 0.39% | 2.22% | Not reported | Q1 2026 |
 UPB | $2.45M | 0.20% | 0.65% | -51.9% | Q4 2024 |
 GOSS | $1.19M | 0.10% | 1.48% | Not reported | Q3 2019 |
| Q1 2026 | |||||
| SRRK | $339M | 32.95% | 5.79% | Not reported | Q1 2022 |
| MLYS | $159M | 15.45% | 7.12% | Not reported | Q1 2023 |
| ALMS | $140M | 13.58% | Not reported | +10.2% | Q3 2024 |
| SEPN | $75.7M | 7.35% | 7.01% | Not reported | Q4 2024 |
| KLRS | $74.7M | 7.26% | 56.31% | Not reported | Q1 2025 |
| SGP | $54.7M | 5.31% | 6.31% | New | Q1 2026 |
| NGNE | $34.6M | 3.36% | 11.00% | Not reported | Q4 2023 |
| IVA | $28.8M | 2.80% | 2.69% | Not reported | Q4 2025 |
| STRO | $26.5M | 2.57% | 6.42% | +419.7% | Q4 2018 |
| JBIO | $13.6M | 1.32% | 1.96% | Not reported | Q2 2025 |
| VTVT | $11.8M | 1.15% | Not reported | Not reported | Q4 2021 |
| AQST | $10.4M | 1.01% | 2.01% | Not reported | Q3 2025 |
| XFOR | $7.57M | 0.74% | 1.94% | -6.5% | Q4 2025 |
| NKTX | $7.4M | 0.72% | 4.92% | Not reported | Q3 2020 |
| ACLX | $6.99M | 0.68% | 0.10% | Not reported | Q1 2022 |
| UPB | $6.62M | 0.64% | 1.35% | Not reported | Q4 2024 |
| ABVX | $6.3M | 0.61% | 0.07% | -25.0% | Q4 2023 |
| AGMB | $6.29M | 0.61% | 1.76% | New | Q1 2026 |
| RANI | $6.25M | 0.61% | Not reported | Not reported | Q4 2025 |
| CHRS | $5.79M | 0.56% | 2.22% | New | Q1 2026 |
 PVLA | $4.79M | 0.47% | 0.27% | -63.3% | Q4 2024 |
| GOSS | $2.37M | 0.23% | 3.08% | Not reported | Q3 2019 |
| Q4 2025 | |||||
| SRRK | $304M | 31.35% | 6.36% | +22.9% | Q1 2022 |
| MLYS | $213M | 21.98% | 7.20% | -6.3% | Q1 2023 |
| KLRS | $109M | 11.27% | 56.54% | +13.1% | Q1 2025 |
| SEPN | $87.8M | 9.06% | 7.03% | Not reported | Q4 2024 |
| ALMS | $56.2M | 5.80% | Not reported | +19.9% | Q3 2024 |
| NGNE | $35.4M | 3.65% | 11.09% | Not reported | Q4 2023 |
| IVA | $24.2M | 2.49% | 2.69% | New | Q4 2025 |
| GOSS | $22.4M | 2.31% | 3.09% | +17.8% | Q3 2019 |
| UPB | $20M | 2.06% | 1.36% | -23.5% | Q4 2024 |
| AQST | $16.2M | 1.67% | 2.05% | Not reported | Q3 2025 |
| JBIO | $14.9M | 1.54% | 1.96% | +82.4% | Q2 2025 |
| VTVT | $11.9M | 1.23% | Not reported | -20.3% | Q4 2021 |
| RANI | $11.5M | 1.18% | Not reported | New | Q4 2025 |
| PVLA | $11M | 1.13% | 0.85% | -50.0% | Q4 2024 |
| ABVX | $10.2M | 1.05% | 0.10% | Not reported | Q4 2023 |
| XFOR | $7.84M | 0.81% | 2.16% | New | Q4 2025 |
| NKTX | $6.49M | 0.67% | 4.93% | -6.9% | Q3 2020 |
| ACLX | $3.97M | 0.41% | 0.11% | -25.0% | Q1 2022 |
| STRO | $2.37M | 0.24% | 2.38% | -6.9% | Q4 2018 |
 CTNM | $826K | 0.09% | 0.31% | -87.4% | Q2 2024 |
 NUVB | $41K | 0.00% | 0.04% | -6.9% | Q2 2022 |
| Q3 2025 | |||||
| MLYS | $237M | 31.01% | 7.93% | +10.4% | Q1 2023 |
| SRRK | $209M | 27.29% | 5.66% | Not reported | Q1 2022 |
| KLRS | $66.2M | 8.64% | 61.21% | Not reported | Q1 2025 |
| SEPN | $59.2M | 7.73% | 7.05% | Not reported | Q4 2024 |
| NGNE | $29.8M | 3.89% | 11.62% | Not reported | Q4 2023 |
| ALMS | $19.2M | 2.50% | Not reported | Not reported | Q3 2024 |
| UPB | $18.1M | 2.36% | 1.78% | -33.3% | Q4 2024 |
| GOSS | $16.1M | 2.10% | 2.65% | Not reported | Q3 2019 |
 LENZ | $16M | 2.09% | 1.20% | Not reported | Q1 2024 |
| AQST | $14M | 1.82% | 2.05% | New | Q3 2025 |
| PVLA | $13.1M | 1.72% | 1.89% | -38.3% | Q4 2024 |
| AVDL | $10.3M | 1.35% | 0.69% | Not reported | Q1 2021 |
| VTVT | $8.74M | 1.14% | Not reported | +81.1% | Q4 2021 |
| NKTX | $7.8M | 1.02% | 5.31% | Not reported | Q3 2020 |
| CTNM | $6.71M | 0.88% | 2.04% | -3.0% | Q2 2024 |
| ACLX | $6.66M | 0.87% | 0.14% | -20.0% | Q1 2022 |
| ABVX | $6.41M | 0.84% | 0.12% | Not reported | Q4 2023 |
| JBIO | $4.58M | 0.60% | 1.63% | Not reported | Q2 2025 |
 AURA | $3.61M | 0.47% | 0.93% | -41.5% | Q2 2025 |
 ZYME | $3.55M | 0.46% | 0.28% | -33.0% | Q1 2022 |
 SRZN | $3.11M | 0.41% | 2.82% | Not reported | Q3 2021 |
 RYTM | $3.06M | 0.40% | 0.05% | -40.0% | Q1 2020 |
| STRO | $1.91M | 0.25% | 2.58% | Not reported | Q4 2018 |
| TERN | $1.02M | 0.13% | 0.15% | -33.0% | Q1 2021 |
 BOLT | $260K | 0.03% | 2.54% | -6.9% | Q1 2021 |
| NUVB | $26.9K | 0.00% | 0.04% | Not reported | Q2 2022 |