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Simplify Asset Management Inc.

13F filer · CIK 0001846368
Reported Jul 16, 2026
Net buyer this quarter
13F portfolio value$7.19BU.S. long equity reported on 13F
Positions12416 new · 21 closed
Net flow last quarter+$97MBuys minus sells
Top 10 positions weight3.4%Concentration

Holdings

13F · last 4 quarters free
Scroll for earlier quarters
CompanyValue% of portfolio% of companyPOSITION CHANGE qoq %First reported
Q2 2026Reported Jul 16, 2026124 positions
NMBNuveen Massachusetts Dividend Advantage Municipal Fund$38.7M0.54%Not reportedNot reportedQ3 2024
PAGPPlains GP Holdings LP$30.9M0.43%0.64%Not reportedQ1 2023
NXTINext Inc$28.6M0.40%Not reportedNot reportedQ2 2024
PCTPureCycle Technologies, Inc.$24.7M0.34%1.52%+72.1%Q1 2023
UTHRUNITED THERAPEUTICS Corp$24.6M0.34%0.11%+32.6%Q4 2021
NVONovo Nordisk A S$24.2M0.34%Not reported+54.2%Q2 2024
JNJJohnson & Johnson$18.5M0.26%0.00%+120.0%Q4 2021
WRBYWarby Parker Inc.$17.8M0.25%0.52%+101.9%Q4 2025
LLYELI LILLY & Co$17.6M0.25%0.00%-11.9%Q4 2021
UNHUnitedhealth Group Inc$17.5M0.24%0.00%+1355.1%Q4 2021
JAZZJazz Pharmaceuticals plc$16.5M0.23%0.11%+32.5%Q4 2025
ABBVAbbVie Inc.$16.2M0.23%0.00%+32.6%Q1 2022
IBITiShares Bitcoin Trust ETF$16.2M0.23%0.03%-30.4%Q3 2025
BHVNBiohaven Ltd.$15.5M0.22%0.69%+15.8%Q2 2025
BNTCBenitec Biopharma Inc.$13.5M0.19%2.92%+78.9%Q2 2024
CASA. M. Castle & Co.$12.4M0.17%5.90%NewQ2 2026
TMOThermo Fisher Scientific Inc.$11.6M0.16%0.01%+32.6%Q4 2021
ALGNAlign Technology Inc$11.3M0.16%0.09%-37.5%Q4 2023
TXG10x Genomics, Inc.$11.2M0.16%0.23%-17.4%Q4 2025
DGXQuest Diagnostics Inc$10.5M0.15%0.04%Not reportedQ1 2025
GILDGilead Sciences, Inc.$10.3M0.14%0.01%+32.6%Q3 2022
ELVElevance Health, Inc.$9.89M0.14%0.01%Not reportedQ4 2021
ACHVAchieve Life Sciences, Inc.$9.35M0.13%1.39%+20.9%Q1 2024
DHRDanaher Corp$8.16M0.11%0.01%+32.6%Q4 2021
AMGNAmgen Inc$7.6M0.11%0.00%+32.4%Q1 2022
CVSCVS HEALTH Corp$7.35M0.10%0.01%+31.6%Q4 2021
AZNAstrazeneca PLC$6.48M0.09%Not reported+32.4%Q1 2025
CAHCardinal Health Inc$6.38M0.09%0.01%Not reportedQ4 2024
EYPTEyePoint, Inc.$5.72M0.08%0.47%+22.7%Q1 2025
ESTAEstablishment Labs Holdings Inc.$5.19M0.07%0.20%+14.2%Q3 2022
VRTXVertex Pharmaceuticals Inc / Ma$5.19M0.07%0.00%+31.8%Q4 2022
MISTMilestone Pharmaceuticals Inc.$4.49M0.06%2.69%+122.3%Q1 2025
TSLATesla, Inc.$4.47M0.06%0.00%-4.3%Q4 2020
HODLVanEck Bitcoin ETF$4.39M0.06%0.45%+26.4%Q1 2025
GHGuardant Health, Inc.$4.14M0.06%0.02%+32.4%Q2 2025
RITMRithm Capital Corp.$3.86M0.05%0.07%+22.3%Q1 2024
DCTHDelcath Systems, Inc.$3.33M0.05%0.76%+1.4%Q4 2024
GEHCGE HealthCare Technologies Inc.$3.33M0.05%0.01%+32.6%Q2 2025
ISRGIntuitive Surgical Inc$2.98M0.04%0.00%-30.4%Q4 2021
PHATPhathom Pharmaceuticals, Inc.$2.7M0.04%0.31%-5.0%Q1 2023
CORTCorcept Therapeutics Inc$2.3M0.03%0.02%-30.0%Q1 2026
ABEOAbeona Therapeutics Inc.$2.13M0.03%0.60%-32.0%Q2 2024
PCRXPacira BioSciences, Inc.$2.11M0.03%0.21%+32.6%Q4 2024
CSCOCisco Systems, Inc.$1.99M0.03%0.00%-14.9%Q3 2022
CLDXCelldex Therapeutics, Inc.$1.98M0.03%0.07%-23.0%Q3 2025
WMTWalmart Inc.$1.91M0.03%0.00%+18.8%Q3 2025
ABTAbbott Laboratories$1.86M0.03%0.00%+32.5%Q4 2021
DXDynex Capital Inc$1.76M0.02%0.06%+64.9%Q4 2025
EWEdwards Lifesciences Corp$1.69M0.02%0.00%+32.6%Q4 2021
KYTXKyverna Therapeutics, Inc.$1.63M0.02%0.30%+5.5%Q4 2025
Q1 2026Reported Apr 27, 2026129 positions
NMBNuveen Massachusetts Dividend Advantage Municipal Fund$37.5M0.58%Not reportedNot reportedQ3 2024
PAGPPlains GP Holdings LP$30.9M0.47%0.64%Not reportedQ1 2023
IBITiShares Bitcoin Trust ETF$26.9M0.41%0.05%-12.0%Q3 2025
NXTINext Inc$24.4M0.37%Not reportedNot reportedQ2 2024
UTHRUNITED THERAPEUTICS Corp$20.3M0.31%0.08%+43.7%Q4 2021
ALGNAlign Technology Inc$18.3M0.28%0.15%-0.3%Q4 2023
LLYELI LILLY & Co$15.4M0.24%0.00%-40.3%Q4 2021
NVONovo Nordisk A S$12M0.18%Not reportedNot reportedQ2 2024
ABBVAbbVie Inc.$10.6M0.16%0.00%+104.5%Q1 2022
JAZZJazz Pharmaceuticals plc$9.78M0.15%0.08%-27.3%Q4 2025
PCTPureCycle Technologies, Inc.$9.19M0.14%0.98%-8.4%Q1 2023
TMOThermo Fisher Scientific Inc.$8.56M0.13%0.00%+276.9%Q4 2021
GILDGilead Sciences, Inc.$8.55M0.13%0.00%+63.7%Q3 2022
REGNRegeneron Pharmaceuticals, Inc.$8.42M0.13%0.01%-65.0%Q2 2022
JNJJohnson & Johnson$8.1M0.12%0.00%+50.8%Q4 2021
BHVNBiohaven Ltd.$7.6M0.12%0.60%-6.2%Q2 2025
TXG10x Genomics, Inc.$7.53M0.12%0.28%-27.0%Q4 2025
MMM3m Co$6.43M0.10%0.01%+886.4%Q1 2024
WRBYWarby Parker Inc.$6.13M0.09%0.26%-27.4%Q4 2025
DHRDanaher Corp$6.12M0.09%0.00%-27.3%Q4 2021
BNTCBenitec Biopharma Inc.$5.99M0.09%1.64%+271.9%Q2 2024
AMGNAmgen Inc$5.57M0.09%0.00%-69.7%Q1 2022
AZNAstrazeneca PLC$5.09M0.08%Not reported-27.3%Q1 2025
ISRGIntuitive Surgical Inc$4.96M0.08%0.00%-27.0%Q4 2021
EYPTEyePoint, Inc.$4.2M0.06%0.39%-13.1%Q1 2025
TSLATesla, Inc.$4.12M0.06%0.00%-13.6%Q4 2020
HODLVanEck Bitcoin ETF$4.01M0.06%0.35%+8.4%Q1 2025
CVSCVS HEALTH Corp$3.88M0.06%0.00%-27.1%Q4 2021
VRTXVertex Pharmaceuticals Inc / Ma$3.54M0.05%0.00%-54.6%Q4 2022
ACHVAchieve Life Sciences, Inc.$3.48M0.05%2.22%Not reportedQ1 2024
ALHCAlignment Healthcare, Inc.$3.4M0.05%0.09%-26.6%Q4 2024
RITMRithm Capital Corp.$3.19M0.05%0.06%+188.7%Q1 2024
ESTAEstablishment Labs Holdings Inc.$3.01M0.05%0.18%-27.3%Q3 2022
PHATPhathom Pharmaceuticals, Inc.$2.92M0.04%0.33%-18.5%Q1 2023
GEHCGE HealthCare Technologies Inc.$2.79M0.04%0.01%-27.3%Q2 2025
DCTHDelcath Systems, Inc.$2.42M0.04%0.76%Not reportedQ4 2024
ABEOAbeona Therapeutics Inc.$2.28M0.03%0.89%+1.5%Q2 2024
CLDXCelldex Therapeutics, Inc.$2.19M0.03%0.10%-18.8%Q3 2025
MFAMfa Financial, Inc.$2M0.03%0.21%+3.2%Q4 2025
GHGuardant Health, Inc.$1.92M0.03%0.02%-29.6%Q2 2025
MISTMilestone Pharmaceuticals Inc.$1.79M0.03%1.28%Not reportedQ1 2025
OCSOculis Holding AG$1.77M0.03%Not reported-32.5%Q4 2025
WMTWalmart Inc.$1.77M0.03%0.00%-8.2%Q3 2025
INSMINSMED Inc$1.76M0.03%0.01%-70.8%Q2 2024
PLTRPalantir Technologies Inc.$1.71M0.03%0.00%+20.2%Q3 2021
ABTAbbott Laboratories$1.59M0.02%0.00%-27.3%Q4 2021
CSCOCisco Systems, Inc.$1.54M0.02%0.00%-2.5%Q3 2022
LONALeonaBio, Inc.$1.53M0.02%1.59%Not reportedQ3 2025
CORTCorcept Therapeutics Inc$1.52M0.02%0.04%NewQ1 2026
KYTXKyverna Therapeutics, Inc.$1.49M0.02%0.29%-10.0%Q4 2025
Q4 2025Reported Feb 9, 2026130 positions
IBITiShares Bitcoin Trust ETF$39.5M0.64%0.06%+25.0%Q3 2025
NMBNuveen Massachusetts Dividend Advantage Municipal Fund$38.8M0.63%Not reportedNot reportedQ3 2024
UNHUnitedhealth Group Inc$32.9M0.54%0.01%+239.9%Q4 2021
LLYELI LILLY & Co$30.1M0.49%0.00%+189.5%Q4 2021
NXTINext Inc$26.7M0.44%Not reportedNot reportedQ2 2024
PAGPPlains GP Holdings LP$24.4M0.40%0.64%Not reportedQ1 2023
REGNRegeneron Pharmaceuticals, Inc.$24M0.39%0.03%+140.0%Q2 2022
AMGNAmgen Inc$17.1M0.28%0.01%Not reportedQ1 2022
ALGNAlign Technology Inc$16.7M0.27%0.15%Not reportedQ4 2023
PCTPureCycle Technologies, Inc.$16.6M0.27%1.07%+227.4%Q1 2023
APLSApellis Pharmaceuticals, Inc.$13.5M0.22%0.42%+403.3%Q3 2025
JAZZJazz Pharmaceuticals plc$12.1M0.20%0.12%NewQ4 2025
UTHRUNITED THERAPEUTICS Corp$11.6M0.19%0.05%+19.7%Q4 2021
BHVNBiohaven Ltd.$10.8M0.18%0.72%+773.6%Q2 2025
DHRDanaher Corp$10.2M0.17%0.01%+449.8%Q4 2021
WRBYWarby Parker Inc.$8.72M0.14%0.35%NewQ4 2025
ISRGIntuitive Surgical Inc$8.35M0.14%0.00%+92.9%Q4 2021
VRTXVertex Pharmaceuticals Inc / Ma$7.93M0.13%0.01%+1327.9%Q4 2022
TXG10x Genomics, Inc.$7.93M0.13%0.38%NewQ4 2025
EYPTEyePoint, Inc.$6.86M0.11%0.45%+314.9%Q1 2025
AZNAstrazeneca PLC$6.53M0.11%Not reported+92.1%Q1 2025
INSMINSMED Inc$6.42M0.10%0.02%+87.6%Q2 2024
ACHVAchieve Life Sciences, Inc.$5.89M0.10%2.23%Not reportedQ1 2024
CVSCVS HEALTH Corp$5.88M0.10%0.01%-12.7%Q4 2021
TSLATesla, Inc.$5.78M0.09%0.00%-47.3%Q4 2020
ABBVAbbVie Inc.$5.43M0.09%0.00%-35.5%Q1 2022
PHATPhathom Pharmaceuticals, Inc.$5.34M0.09%0.45%Not reportedQ1 2023
ESTAEstablishment Labs Holdings Inc.$5.31M0.09%0.25%+92.1%Q3 2022
ALHCAlignment Healthcare, Inc.$5.19M0.08%0.13%+92.0%Q4 2024
PENPenumbra Inc$4.92M0.08%0.04%+89.7%Q2 2023
HODLVanEck Bitcoin ETF$4.77M0.08%0.30%-17.9%Q1 2025
GILDGilead Sciences, Inc.$4.6M0.08%0.00%-37.7%Q3 2022
JNJJohnson & Johnson$4.54M0.07%0.00%+92.6%Q4 2021
GEHCGE HealthCare Technologies Inc.$4.43M0.07%0.01%+91.7%Q2 2025
MLYSMineralys Therapeutics, Inc.$4.14M0.07%0.14%-47.8%Q3 2025
IQVIqvia Holdings Inc.$3.93M0.06%0.01%+92.6%Q4 2021
VRDNViridian Therapeutics, Inc.\DE$3.22M0.05%0.10%+107.1%Q3 2025
MISTMilestone Pharmaceuticals Inc.$3.04M0.05%1.42%-46.8%Q1 2025
GHGuardant Health, Inc.$3.02M0.05%0.02%-4.9%Q2 2025
OSCROscar Health, Inc.$2.95M0.05%Not reportedNewQ4 2025
TMOThermo Fisher Scientific Inc.$2.68M0.04%0.00%+89.7%Q4 2021
ABTAbbott Laboratories$2.67M0.04%0.00%+91.5%Q4 2021
DCTHDelcath Systems, Inc.$2.64M0.04%0.75%Not reportedQ4 2024
ABEOAbeona Therapeutics Inc.$2.64M0.04%0.91%-11.5%Q2 2024
ARGXArgenx SE$2.62M0.04%0.01%+87.8%Q2 2023
HQYHealthequity, Inc.$2.5M0.04%0.03%+72.9%Q3 2025
CLDXCelldex Therapeutics, Inc.$2.31M0.04%0.13%Not reportedQ3 2025
ABVXAbivax S.A.$2.29M0.04%0.02%-72.4%Q3 2025
PCRXPacira BioSciences, Inc.$2.23M0.04%0.21%+91.9%Q4 2024
CYPHCypherpunk Technologies Inc.$2.17M0.04%2.23%+91.9%Q1 2024
Q3 2025Reported Oct 20, 2025113 positions
IBITiShares Bitcoin Trust ETF$41.3M0.76%0.05%NewQ3 2025
NMBNuveen Massachusetts Dividend Advantage Municipal Fund$39.2M0.72%Not reported-42.8%Q3 2024
NXTINext Inc$26.9M0.49%Not reported+3587.0%Q2 2024
PAGPPlains GP Holdings LP$23.2M0.43%0.64%Not reportedQ1 2023
TSLATesla, Inc.$10.8M0.20%0.00%+0.9%Q4 2020
UNHUnitedhealth Group Inc$10.1M0.19%0.00%+624.8%Q4 2021
ABBVAbbVie Inc.$8.54M0.16%0.00%+100.6%Q1 2022
UTHRUNITED THERAPEUTICS Corp$8.35M0.15%0.05%Not reportedQ4 2021
MLYSMineralys Therapeutics, Inc.$8.29M0.15%0.28%NewQ3 2025
PCTPureCycle Technologies, Inc.$7.77M0.14%0.33%+13.8%Q1 2023
HODLVanEck Bitcoin ETF$7.61M0.14%0.37%-5.5%Q1 2025
LLYELI LILLY & Co$7.37M0.14%0.00%-31.5%Q4 2021
REGNRegeneron Pharmaceuticals, Inc.$7.3M0.13%0.01%+251.1%Q2 2022
AKROAkero Therapeutics, Inc.$6.91M0.13%0.18%Not reportedQ1 2023
GILDGilead Sciences, Inc.$6.68M0.12%0.00%+13.8%Q3 2022
CVSCVS HEALTH Corp$6.4M0.12%0.01%+80.8%Q4 2021
ARQTArcutis Biotherapeutics, Inc.$5.99M0.11%0.26%-22.3%Q4 2024
EYENational Vision Holdings, Inc.$5.77M0.11%0.25%-29.7%Q2 2025
MISTMilestone Pharmaceuticals Inc.$5.67M0.10%3.33%+186.2%Q1 2025
ABVXAbivax S.A.$5.22M0.10%0.10%NewQ3 2025
NBIXNeurocrine Biosciences Inc$5.14M0.09%0.04%-21.2%Q2 2024
NKTRNektar Therapeutics$4.96M0.09%0.44%+67.7%Q2 2025
PHATPhathom Pharmaceuticals, Inc.$3.79M0.07%0.45%-38.3%Q1 2023
ACHVAchieve Life Sciences, Inc.$3.73M0.07%2.24%Not reportedQ1 2024
ISRGIntuitive Surgical Inc$3.42M0.06%0.00%-12.2%Q4 2021
MRUSMerus N.V.$3.14M0.06%0.04%NewQ3 2025
ABEOAbeona Therapeutics Inc.$2.98M0.05%1.08%+1.2%Q2 2024
AZNAstrazeneca PLC$2.83M0.05%Not reported+13.9%Q1 2025
INSMINSMED Inc$2.83M0.05%0.01%+26.6%Q2 2024
DCTHDelcath Systems, Inc.$2.81M0.05%0.74%+144.9%Q4 2024
APLTApplied Therapeutics, Inc.$2.71M0.05%3.11%Not reportedQ1 2023
APLSApellis Pharmaceuticals, Inc.$2.42M0.04%0.08%NewQ3 2025
ALHCAlignment Healthcare, Inc.$2.39M0.04%0.07%+13.8%Q4 2024
CORCencora, Inc.$2.31M0.04%0.00%-15.4%Q2 2025
CLDXCelldex Therapeutics, Inc.$2.2M0.04%0.13%NewQ3 2025
GEHCGE HealthCare Technologies Inc.$2.12M0.04%0.01%+13.8%Q2 2025
JNJJohnson & Johnson$2.11M0.04%0.00%+14.0%Q4 2021
PENPenumbra Inc$2.11M0.04%0.02%Not reportedQ2 2023
GHGuardant Health, Inc.$1.94M0.04%0.02%+16.8%Q2 2025
CAHCardinal Health Inc$1.91M0.04%0.01%-47.4%Q4 2024
IQVIqvia Holdings Inc.$1.72M0.03%0.01%+13.9%Q4 2021
WGSGeneDx Holdings Corp.$1.68M0.03%0.05%-72.4%Q2 2025
CMPSCOMPASS Pathways plc$1.66M0.03%0.30%Not reportedQ4 2024
TCRXTScan Therapeutics, Inc.$1.65M0.03%3.77%-13.6%Q1 2023
BHVNBiohaven Ltd.$1.65M0.03%0.10%+13.8%Q2 2025
DHRDanaher Corp$1.6M0.03%0.00%-55.7%Q4 2021
RITMRithm Capital Corp.$1.58M0.03%0.03%Not reportedQ1 2024
ESTAEstablishment Labs Holdings Inc.$1.56M0.03%0.13%Not reportedQ3 2022
PLTRPalantir Technologies Inc.$1.54M0.03%0.00%Not reportedQ3 2021
HQYHealthequity, Inc.$1.5M0.03%0.02%NewQ3 2025
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