Knott David M Jr
Net seller this quarter
$189M
76
-$3.86M
62.8%
Holdings
| Company | Value | % of portfolio | % of company | POSITION CHANGE qoq % | First reported |
|---|---|---|---|---|---|
| Q2 2026 | |||||
 GOOG | $32.3M | 17.07% | Not reported | Not reported | Q4 2021 |
 APO | $26.6M | 14.07% | 0.04% | Not reported | Q4 2021 |
 SNDX | $9.56M | 5.05% | 0.49% | +3.6% | Q1 2024 |
 XERS | $8.4M | 4.44% | 0.61% | Not reported | Q4 2023 |
 TVTX | $8.37M | 4.42% | 0.16% | +4.7% | Q3 2023 |
 PTGX | $7.72M | 4.08% | 0.10% | Not reported | Q3 2023 |
 BBIO | $6.92M | 3.66% | 0.05% | +3.2% | Q1 2022 |
 IOVA | $6.66M | 3.52% | 0.35% | Not reported | Q4 2021 |
 ALKS | $6.38M | 3.37% | 0.07% | +1.5% | Q2 2023 |
 JPM | $5.92M | 3.13% | 0.00% | -7.1% | Q4 2021 |
 COGT | $4.3M | 2.27% | 0.06% | +6.8% | Q1 2025 |
 TGTX | $3.67M | 1.94% | 0.04% | -25.7% | Q4 2021 |
 CLST | $3.58M | 1.89% | 2.83% | New | Q2 2026 |
 AGIO | $3.53M | 1.86% | 0.16% | +2.2% | Q4 2025 |
 VRDN | $3.32M | 1.76% | 0.16% | Not reported | Q4 2024 |
 RLMD | $3.12M | 1.65% | 0.42% | +2.7% | Q4 2021 |
 RCUS | $2.5M | 1.32% | 0.06% | Not reported | Q1 2025 |
 HELP | $2.45M | 1.29% | 0.72% | +5.7% | Q4 2024 |
 RZLT | $1.92M | 1.02% | 0.38% | Not reported | Q3 2025 |
 AB | $1.69M | 0.89% | 0.05% | Not reported | Q4 2021 |
 MDGL | $1.61M | 0.85% | 0.01% | +50.0% | Q3 2022 |
 ATRC | $1.44M | 0.76% | 0.10% | Not reported | Q1 2025 |
 DCGO | $1.38M | 0.73% | 2.70% | Not reported | Q4 2021 |
 ARDX | $1.34M | 0.71% | 0.11% | +27.1% | Q3 2022 |
 RARE | $1.27M | 0.67% | 0.04% | +15.1% | Q1 2025 |
 CGEM | $1.26M | 0.67% | 0.11% | +185.9% | Q1 2026 |
 JNJ | $1.25M | 0.66% | 0.00% | Not reported | Q4 2021 |
 VERA | $1.12M | 0.59% | 0.04% | Not reported | Q1 2025 |
 OBIO | $1.09M | 0.58% | 0.42% | Not reported | Q2 2025 |
 SPRB | $1.08M | 0.57% | 0.73% | New | Q2 2026 |
 CNTB | $1.06M | 0.56% | 0.71% | +14.7% | Q4 2025 |
 BIIB | $864K | 0.46% | 0.00% | Not reported | Q3 2025 |
 PFE | $779K | 0.41% | 0.00% | Not reported | Q4 2021 |
 AAPL | $722K | 0.38% | 0.00% | Not reported | Q4 2021 |
 CNQ | $664K | 0.35% | 0.00% | Not reported | Q4 2021 |
 PTHS | $624K | 0.33% | 0.59% | +4.8% | Q3 2025 |
 IBM | $602K | 0.32% | 0.00% | Not reported | Q1 2023 |
 MSFT | $597K | 0.32% | 0.00% | Not reported | Q4 2021 |
 VSTM | $592K | 0.31% | 0.17% | +49.0% | Q1 2026 |
 KURA | $579K | 0.31% | 0.06% | Not reported | Q2 2024 |
 SLDB | $562K | 0.30% | 0.05% | +19.2% | Q1 2025 |
 INSM | $453K | 0.24% | 0.00% | New | Q2 2026 |
 LBRX | $421K | 0.22% | 0.05% | New | Q2 2026 |
 CDNA | $388K | 0.21% | 0.03% | New | Q2 2026 |
 QTTB | $387K | 0.20% | 0.13% | New | Q2 2026 |
 ELVN | $314K | 0.17% | 0.01% | New | Q2 2026 |
 RHP | $309K | 0.16% | 0.00% | Not reported | Q4 2021 |
 AVGO | $268K | 0.14% | 0.00% | Not reported | Q2 2022 |
 KMB | $263K | 0.14% | 0.00% | Not reported | Q4 2021 |
 NVDA | $256K | 0.14% | 0.00% | Not reported | Q2 2022 |
| Q1 2026 | |||||
| GOOG | $26.2M | 15.61% | Not reported | Not reported | Q4 2021 |
| APO | $25.1M | 14.92% | 0.04% | Not reported | Q4 2021 |
| SNDX | $9.86M | 5.87% | 0.48% | +1.7% | Q1 2024 |
| BBIO | $6.68M | 3.98% | 0.05% | +5.9% | Q1 2022 |
| PTGX | $6.64M | 3.95% | 0.10% | -13.7% | Q3 2023 |
| XERS | $6.15M | 3.66% | 0.61% | +9.3% | Q4 2023 |
| JPM | $5.73M | 3.41% | 0.00% | Not reported | Q4 2021 |
| IOVA | $5.62M | 3.34% | 0.37% | Not reported | Q4 2021 |
| ALKS | $4.24M | 2.53% | 0.07% | +26.3% | Q2 2023 |
| TVTX | $4.18M | 2.49% | 0.15% | -24.4% | Q3 2023 |
| COGT | $4M | 2.38% | 0.06% | +2.0% | Q1 2025 |
| VRDN | $3.54M | 2.11% | 0.18% | +24.8% | Q4 2024 |
| AGIO | $3.15M | 1.87% | 0.16% | +417.0% | Q4 2025 |
| RLMD | $3.06M | 1.82% | 0.42% | Not reported | Q4 2021 |
| TGTX | $2.99M | 1.78% | 0.06% | +100.0% | Q4 2021 |
| CPRX | $2.97M | 1.77% | 0.10% | -36.5% | Q4 2023 |
| ACLX | $2.23M | 1.33% | 0.03% | -24.4% | Q1 2023 |
| AB | $1.8M | 1.07% | 0.05% | Not reported | Q4 2021 |
| RCUS | $1.75M | 1.04% | 0.06% | -33.0% | Q1 2025 |
| DCGO | $1.68M | 1.00% | 2.70% | Not reported | Q4 2021 |
| HELP | $1.68M | 1.00% | 0.68% | +22.7% | Q4 2024 |
 CYTK | $1.56M | 0.93% | 0.02% | -30.5% | Q1 2024 |
| CNTA | $1.55M | 0.92% | 0.03% | +875.0% | Q4 2025 |
| ATRC | $1.47M | 0.87% | 0.10% | Not reported | Q1 2025 |
| ARDX | $1.24M | 0.74% | 0.08% | Not reported | Q3 2022 |
| JNJ | $1.2M | 0.72% | 0.00% | -28.9% | Q4 2021 |
| RZLT | $1.13M | 0.67% | 0.38% | +8.8% | Q3 2025 |
| OBIO | $1.08M | 0.64% | 0.43% | +1.5% | Q2 2025 |
| MDGL | $1.05M | 0.62% | 0.01% | Not reported | Q3 2022 |
| VERA | $1.05M | 0.62% | 0.04% | Not reported | Q1 2025 |
| CNTB | $1.02M | 0.60% | 0.62% | +93.9% | Q4 2025 |
| PFE | $908K | 0.54% | 0.00% | Not reported | Q4 2021 |
 BMY | $826K | 0.49% | 0.00% | -38.1% | Q4 2021 |
| CNQ | $819K | 0.49% | 0.00% | Not reported | Q4 2021 |
| BIIB | $733K | 0.44% | 0.00% | -33.3% | Q3 2025 |
| RARE | $693K | 0.41% | 0.03% | +65.3% | Q1 2025 |
| AAPL | $633K | 0.38% | 0.00% | Not reported | Q4 2021 |
| MSFT | $592K | 0.35% | 0.00% | Not reported | Q4 2021 |
| VSTM | $551K | 0.33% | 0.12% | New | Q1 2026 |
 ADMA | $542K | 0.32% | 0.03% | Not reported | Q4 2021 |
| IBM | $519K | 0.31% | 0.00% | Not reported | Q1 2023 |
| PTHS | $443K | 0.26% | 0.63% | +9.3% | Q3 2025 |
| KURA | $429K | 0.26% | 0.06% | +34.6% | Q2 2024 |
 EOLS | $408K | 0.24% | 0.15% | Not reported | Q1 2023 |
| CGEM | $344K | 0.20% | 0.04% | New | Q1 2026 |
| SLDB | $339K | 0.20% | 0.05% | -71.0% | Q1 2025 |
 LENZ | $309K | 0.18% | 0.11% | -37.2% | Q2 2025 |
 WVE | $290K | 0.17% | 0.02% | -55.6% | Q1 2025 |
 RAIN | $258K | 0.15% | Not reported | New | Q1 2026 |
| KMB | $232K | 0.14% | 0.00% | Not reported | Q4 2021 |
| Q4 2025 | |||||
 CLMT | $44M | 20.38% | 2.55% | -21.6% | Q4 2021 |
| APO | $32.6M | 15.08% | 0.04% | Not reported | Q4 2021 |
| GOOG | $28.7M | 13.28% | Not reported | -18.5% | Q4 2021 |
| SNDX | $8.72M | 4.04% | 0.47% | -3.0% | Q1 2024 |
| XERS | $7.61M | 3.53% | 0.58% | -4.4% | Q4 2023 |
| TVTX | $7.11M | 3.29% | 0.20% | -28.5% | Q3 2023 |
| BBIO | $6.5M | 3.01% | 0.04% | Not reported | Q1 2022 |
| PTGX | $6.38M | 2.95% | 0.12% | -12.1% | Q3 2023 |
| JPM | $6.28M | 2.91% | 0.00% | -4.4% | Q4 2021 |
| VRDN | $4.51M | 2.09% | 0.14% | +24.4% | Q4 2024 |
| CPRX | $4.41M | 2.04% | 0.15% | Not reported | Q4 2023 |
| COGT | $3.62M | 1.68% | 0.06% | Not reported | Q1 2025 |
| RCUS | $2.89M | 1.34% | 0.10% | +27.4% | Q1 2025 |
| ALKS | $2.66M | 1.23% | 0.06% | +392.2% | Q2 2023 |
| DCGO | $2.34M | 1.09% | 2.71% | -13.0% | Q4 2021 |
| HELP | $2.33M | 1.08% | 1.32% | +103.4% | Q4 2024 |
| CYTK | $2.16M | 1.00% | 0.03% | +13.3% | Q1 2024 |
| ATRC | $2.03M | 0.94% | 0.10% | +7.1% | Q1 2025 |
| AB | $1.85M | 0.86% | 0.05% | Not reported | Q4 2021 |
| ACLX | $1.68M | 0.78% | 0.04% | Not reported | Q1 2023 |
 TECX | $1.54M | 0.71% | 0.39% | Not reported | Q1 2025 |
| WVE | $1.53M | 0.71% | 0.05% | Not reported | Q1 2025 |
| JNJ | $1.43M | 0.66% | 0.00% | Not reported | Q4 2021 |
| TGTX | $1.34M | 0.62% | 0.03% | Not reported | Q4 2021 |
| VERA | $1.32M | 0.61% | 0.04% | Not reported | Q1 2025 |
 BHVN | $1.25M | 0.58% | 0.08% | Not reported | Q1 2022 |
| BMY | $1.19M | 0.55% | 0.00% | -18.5% | Q4 2021 |
| MDGL | $1.16M | 0.54% | 0.01% | Not reported | Q3 2022 |
| ADMA | $1.1M | 0.51% | 0.03% | Not reported | Q4 2021 |
| BIIB | $1.06M | 0.49% | 0.00% | +200.0% | Q3 2025 |
| OBIO | $1.04M | 0.48% | 0.44% | +28.2% | Q2 2025 |
| SLDB | $916K | 0.42% | 0.21% | Not reported | Q1 2025 |
| LENZ | $860K | 0.40% | 0.17% | -34.5% | Q2 2025 |
| PFE | $805K | 0.37% | 0.00% | -56.6% | Q4 2021 |
| RZLT | $802K | 0.37% | 0.36% | +23.6% | Q3 2025 |
| MSFT | $774K | 0.36% | 0.00% | Not reported | Q4 2021 |
| AAPL | $678K | 0.31% | 0.00% | Not reported | Q4 2021 |
| EOLS | $661K | 0.31% | 0.15% | Not reported | Q1 2023 |
 NKTR | $655K | 0.30% | 0.08% | New | Q4 2025 |
| IBM | $634K | 0.29% | 0.00% | Not reported | Q1 2023 |
 SRRK | $613K | 0.28% | 0.01% | +54.6% | Q3 2025 |
| PTHS | $598K | 0.28% | 0.60% | +215.5% | Q3 2025 |
| CNQ | $569K | 0.26% | 0.00% | Not reported | Q4 2021 |
| CNTB | $564K | 0.26% | 0.35% | New | Q4 2025 |
 XENE | $491K | 0.23% | 0.01% | Not reported | Q4 2021 |
| AGIO | $490K | 0.23% | 0.03% | New | Q4 2025 |
| RARE | $460K | 0.21% | 0.02% | -61.5% | Q1 2025 |
| MRSN | $438K | 0.20% | 2.23% | New | Q4 2025 |
| KURA | $407K | 0.19% | 0.04% | -41.7% | Q2 2024 |
 FATE | $359K | 0.17% | 0.32% | Not reported | Q3 2025 |
| Q3 2025 | |||||
| CLMT | $51.6M | 20.79% | 3.26% | -13.7% | Q4 2021 |
| APO | $30M | 12.09% | 0.04% | Not reported | Q4 2021 |
| GOOG | $27.3M | 11.02% | Not reported | Not reported | Q4 2021 |
| XERS | $8.26M | 3.33% | 0.61% | -4.3% | Q4 2023 |
| SNDX | $6.58M | 2.66% | 0.49% | +21.3% | Q1 2024 |
| JPM | $6.43M | 2.59% | 0.00% | -2.9% | Q4 2021 |
| TVTX | $6.21M | 2.51% | 0.29% | Not reported | Q3 2023 |
| AVDL | $5.54M | 2.24% | 0.37% | -14.8% | Q4 2021 |
| PTGX | $5.51M | 2.22% | 0.13% | +3.8% | Q3 2023 |
| BBIO | $4.41M | 1.78% | 0.04% | +6.3% | Q1 2022 |
| DCGO | $4.18M | 1.68% | 3.14% | Not reported | Q4 2021 |
| VRNA | $4.09M | 1.65% | 0.01% | -30.3% | Q4 2023 |
| LENZ | $3.82M | 1.54% | 0.29% | Not reported | Q2 2025 |
| CPRX | $3.72M | 1.50% | 0.15% | +7.4% | Q4 2023 |
| RZLT | $2.59M | 1.04% | 0.30% | New | Q3 2025 |
| VRDN | $2.52M | 1.01% | 0.14% | +27.4% | Q4 2024 |
 CSX | $2.48M | 1.00% | 0.00% | Not reported | Q1 2023 |
 LQDA | $2.45M | 0.99% | 0.12% | +19.8% | Q4 2021 |
| ACLX | $2.11M | 0.85% | 0.04% | Not reported | Q1 2023 |
| PFE | $1.9M | 0.77% | 0.00% | Not reported | Q4 2021 |
| AB | $1.83M | 0.74% | 0.05% | Not reported | Q4 2021 |
| ATRC | $1.69M | 0.68% | 0.10% | +3.4% | Q1 2025 |
| CYTK | $1.65M | 0.66% | 0.03% | Not reported | Q1 2024 |
| RARE | $1.56M | 0.63% | 0.05% | Not reported | Q1 2025 |
 PRAX | $1.48M | 0.60% | 0.13% | New | Q3 2025 |
| RCUS | $1.29M | 0.52% | 0.09% | +36.0% | Q1 2025 |
| JNJ | $1.28M | 0.52% | 0.00% | Not reported | Q4 2021 |
| BMY | $1.22M | 0.49% | 0.00% | Not reported | Q4 2021 |
 ABBV | $1.17M | 0.47% | 0.00% | Not reported | Q4 2021 |
| TECX | $1.16M | 0.47% | 0.40% | Not reported | Q1 2025 |
| RHP | $1.08M | 0.43% | 0.02% | Not reported | Q4 2021 |
| SLDB | $1M | 0.40% | 0.21% | Not reported | Q1 2025 |
| DAWN | $920K | 0.37% | 0.13% | +287.1% | Q2 2025 |
| MDGL | $917K | 0.37% | 0.01% | Not reported | Q3 2022 |
| MSFT | $829K | 0.33% | 0.00% | Not reported | Q4 2021 |
| HELP | $826K | 0.33% | 0.65% | +109.7% | Q4 2024 |
| VERA | $756K | 0.30% | 0.04% | +30.0% | Q1 2025 |
 CTVA | $747K | 0.30% | 0.00% | Not reported | Q4 2021 |
| KMB | $746K | 0.30% | 0.00% | Not reported | Q4 2021 |
 DD | $734K | 0.30% | 0.00% | Not reported | Q4 2021 |
| WVE | $659K | 0.27% | 0.06% | +125.0% | Q1 2025 |
| AAPL | $635K | 0.26% | 0.00% | Not reported | Q4 2021 |
 MREO | $619K | 0.25% | 0.04% | -6.0% | Q1 2024 |
| IBM | $604K | 0.24% | 0.00% | Not reported | Q1 2023 |
| KURA | $596K | 0.24% | 0.08% | Not reported | Q2 2024 |
| ALKS | $579K | 0.23% | 0.01% | -60.6% | Q2 2023 |
| CNQ | $537K | 0.22% | 0.00% | Not reported | Q4 2021 |
 MDLZ | $500K | 0.20% | 0.00% | Not reported | Q4 2021 |
| OBIO | $484K | 0.20% | 0.35% | +95.0% | Q2 2025 |
| FATE | $460K | 0.19% | 0.32% | New | Q3 2025 |