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Deerfield Management Company, L.P.

13F filer · CIK 0001009258
Reported Aug 14, 2026
Net seller this quarter
13F portfolio value$9.59BU.S. long equity reported on 13F
Positions7111 new · 11 closed
Net flow last quarter-$285MBuys minus sells
Top 10 positions weight47.9%Concentration

Holdings

13F · last 4 quarters free
Scroll for earlier quarters
CompanyValue% of portfolio% of companyPOSITION CHANGE qoq %First reported
Q2 2026Reported Aug 14, 202671 positions
NUVLNuvalent, Inc.$2.13B22.22%551.18%Not reportedQ3 2021
RVMDRevolution Medicines, Inc.$448M4.67%1.12%+4.1%Q1 2020
PRAXPraxis Precision Medicines, Inc.$323M3.36%3.45%Not reportedQ4 2020
VTRSViatris Inc$321M3.35%1.74%Not reportedQ4 2020
CNCCentene Corp$315M3.28%0.99%-17.2%Q4 2013
UTHRUNITED THERAPEUTICS Corp$248M2.58%1.07%Not reportedQ1 2025
LEGNLegend Biotech Corp$235M2.45%2.20%+5.9%Q4 2024
COGTCogent Biosciences, Inc.$194M2.02%2.92%-44.7%Q4 2020
GMABGenmab A/S$189M1.97%Not reported+178.8%Q1 2026
BKDBrookdale Senior Living Inc.$187M1.95%4.87%Not reportedQ3 2015
VERAVera Therapeutics, Inc.$168M1.75%5.46%+5.2%Q1 2023
IONSIonis Pharmaceuticals Inc$157M1.64%1.20%Not reportedQ4 2016
CELCCelcuity Inc.$152M1.58%2.97%-15.3%Q3 2025
BCRXBiocryst Pharmaceuticals Inc$151M1.57%5.91%+0.4%Q3 2013
NAMSNewAmsterdam Pharma Co N.V.$145M1.51%3.62%Not reportedQ4 2022
ACHCAcadia Healthcare Company, Inc.$133M1.39%4.97%Not reportedQ4 2017
TNGXTango Therapeutics, Inc.$131M1.37%2.49%+1.1%Q3 2023
AHCOAdaptHealth Corp.$120M1.25%8.42%Not reportedQ4 2019
PHVSPharvaris N.V.$117M1.22%5.18%+8.0%Q1 2021
ARWRArrowhead Pharmaceuticals, Inc.$113M1.18%0.98%-11.7%Q4 2013
DNTHDianthus Therapeutics, Inc.$110M1.14%2.05%+10.4%Q1 2026
LRMRLarimar Therapeutics, Inc.$109M1.13%34.28%Not reportedQ2 2020
MLYSMineralys Therapeutics, Inc.$107M1.11%4.48%Not reportedQ1 2023
IDYAIDEAYA Biosciences, Inc.$101M1.06%2.82%+77.4%Q2 2019
XENEXenon Pharmaceuticals Inc.$97.5M1.02%1.67%Not reportedQ2 2025
SVRASavara Inc$83.6M0.87%6.61%Not reportedQ3 2018
LNTHLantheus Holdings, Inc.$83.5M0.87%1.15%-9.1%Q1 2024
SNDXSyndax Pharmaceuticals Inc$82.6M0.86%4.24%Not reportedQ1 2017
BMRNBiomarin Pharmaceutical Inc$76.3M0.80%0.69%+56.5%Q2 2013
PFEPfizer Inc$73.2M0.76%0.05%Not reportedQ2 2013
INDVIndivior Pharmaceuticals, Inc.$67.7M0.71%1.35%-46.8%Q3 2024
BIOBio-Rad Laboratories, Inc.$66.4M0.69%0.82%Not reportedQ3 2023
SPRYARS Pharmaceuticals, Inc.$60.1M0.63%7.55%Not reportedQ4 2022
STOKStoke Therapeutics, Inc.$59.7M0.62%2.92%Not reportedQ4 2025
GPCRStructure Therapeutics Inc.$58.3M0.61%0.51%+41.4%Q1 2023
NVSTEnvista Holdings Corp$58.2M0.61%1.36%Not reportedQ3 2024
INSPInspire Medical Systems, Inc.$57.9M0.60%4.49%-52.0%Q3 2018
CDNACareDx, Inc.$56.9M0.59%3.88%-8.8%Q3 2014
BSXBoston Scientific Corp$56.1M0.59%0.09%Not reportedQ2 2015
BLTEBelite Bio, Inc$55M0.57%0.91%+17.5%Q4 2025
PBLSParabilis Medicines, Inc.$51.5M0.54%1.54%NewQ2 2026
CERTCertara, Inc.$49.2M0.51%4.93%-3.8%Q4 2020
IRONDisc Medicine, Inc.$48.1M0.50%1.71%Not reportedQ2 2023
BBOTBridgeBio Oncology Therapeutics, Inc.$37.2M0.39%6.10%Not reportedQ3 2025
TYRATyra Biosciences, Inc.$32.5M0.34%1.70%+85.3%Q3 2021
MNPRMonopar Therapeutics$30M0.31%4.82%Not reportedQ3 2025
SIONSionna Therapeutics, Inc.$30M0.31%1.51%-29.9%Q1 2025
AVLNAvalyn Pharma Inc.$24.1M0.25%1.65%NewQ2 2026
FHTXFoghorn Therapeutics Inc.$21.4M0.22%7.48%Not reportedQ1 2022
BBNXBeta Bionics, Inc.$20.7M0.22%2.94%Not reportedQ1 2025
Q1 2026Reported May 15, 202671 positions
NUVLNuvalent, Inc.$1.77B20.85%551.18%Not reportedQ3 2021
COGTCogent Biosciences, Inc.$348M4.11%5.30%Not reportedQ4 2020
PRAXPraxis Precision Medicines, Inc.$310M3.66%3.46%+6.6%Q4 2020
VTRSViatris Inc$273M3.22%1.75%Not reportedQ4 2020
UTHRUNITED THERAPEUTICS Corp$271M3.20%1.08%+7.3%Q1 2025
RVMDRevolution Medicines, Inc.$223M2.64%1.15%-20.7%Q1 2020
CELCCelcuity Inc.$196M2.31%3.55%Not reportedQ3 2025
CNCCentene Corp$194M2.29%1.20%-8.2%Q4 2013
LRMRLarimar Therapeutics, Inc.$160M1.89%34.28%+16.3%Q2 2020
BKDBrookdale Senior Living Inc.$159M1.88%4.87%Not reportedQ3 2015
VERAVera Therapeutics, Inc.$150M1.77%5.82%-8.3%Q1 2023
IONSIonis Pharmaceuticals Inc$149M1.75%1.19%Not reportedQ4 2016
BCRXBiocryst Pharmaceuticals Inc$143M1.69%5.92%+4.9%Q3 2013
INSPInspire Medical Systems, Inc.$139M1.64%9.39%+79.5%Q3 2018
LEGNLegend Biotech Corp$139M1.64%2.08%+29.6%Q4 2024
AHCOAdaptHealth Corp.$137M1.61%8.44%Not reportedQ4 2019
NAMSNewAmsterdam Pharma Co N.V.$137M1.61%3.66%+2.4%Q4 2022
ACHCAcadia Healthcare Company, Inc.$106M1.25%4.98%Not reportedQ4 2017
ARWRArrowhead Pharmaceuticals, Inc.$98.6M1.16%1.12%-14.2%Q4 2013
CPRXCatalyst Pharmaceuticals, Inc.$97.6M1.15%3.23%-19.7%Q3 2022
INDVIndivior Pharmaceuticals, Inc.$94.4M1.11%2.48%-8.7%Q3 2024
XENEXenon Pharmaceuticals Inc.$94M1.11%1.67%+198.1%Q2 2025
PHVSPharvaris N.V.$88.3M1.04%4.79%Not reportedQ1 2021
SNDXSyndax Pharmaceuticals Inc$88.3M1.04%4.27%Not reportedQ1 2017
TNGXTango Therapeutics, Inc.$86.8M1.02%2.88%+42.7%Q3 2023
DNTHDianthus Therapeutics, Inc.$85.6M1.01%1.87%NewQ1 2026
PFEPfizer Inc$85.4M1.01%0.05%Not reportedQ2 2013
NBIXNeurocrine Biosciences Inc$80.4M0.95%0.61%-48.5%Q1 2014
DAWNDay One Biopharmaceuticals, Inc.$79.8M0.94%3.60%Not reportedQ2 2021
SVRASavara Inc$74.1M0.87%6.62%Not reportedQ3 2018
EHABEnhabit, Inc.$66.9M0.79%9.36%Not reportedQ3 2022
GMABGenmab A/S$66.1M0.78%Not reportedNewQ1 2026
BIOBio-Rad Laboratories, Inc.$63M0.74%0.82%Not reportedQ3 2023
LNTHLantheus Holdings, Inc.$62.8M0.74%1.27%Not reportedQ1 2024
SPRYARS Pharmaceuticals, Inc.$60.3M0.71%7.56%Not reportedQ4 2022
STOKStoke Therapeutics, Inc.$59.4M0.70%2.93%Not reportedQ4 2025
NVSTEnvista Holdings Corp$56.1M0.66%1.35%-3.1%Q3 2024
IDYAIDEAYA Biosciences, Inc.$51M0.60%1.74%-28.9%Q2 2019
BLTEBelite Bio, Inc$48.5M0.57%0.77%+30.0%Q4 2025
BMRNBiomarin Pharmaceutical Inc$48.1M0.57%0.44%Not reportedQ2 2013
KYMRKymera Therapeutics, Inc.$46.7M0.55%0.68%Not reportedQ4 2024
CERTCertara, Inc.$44.5M0.53%5.09%Not reportedQ4 2020
BBOTBridgeBio Oncology Therapeutics, Inc.$43.7M0.52%6.10%Not reportedQ3 2025
IRONDisc Medicine, Inc.$42M0.50%1.72%+28.5%Q2 2023
SIONSionna Therapeutics, Inc.$38.9M0.46%2.15%Not reportedQ1 2025
CDNACareDx, Inc.$38M0.45%4.27%Not reportedQ3 2014
GPCRStructure Therapeutics Inc.$37M0.44%0.36%Not reportedQ1 2023
VCYTVeracyte, Inc.$23.4M0.28%0.91%Not reportedQ2 2015
ALNYAlnylam Pharmaceuticals, Inc.$22.5M0.27%0.05%Not reportedQ2 2013
EMBCEmbecta Corp.$22.4M0.26%4.27%-7.9%Q4 2023
Q4 2025Reported Feb 17, 2026138 positions
NUVLNuvalent, Inc.$1.74B22.16%551.18%-4.1%Q3 2021
COGTCogent Biosciences, Inc.$321M4.10%5.62%-0.1%Q4 2020
PRAXPraxis Precision Medicines, Inc.$266M3.40%3.59%+7.4%Q4 2020
CNCCentene Corp$265M3.39%1.31%-28.7%Q4 2013
VTRSViatris Inc$252M3.21%1.75%-16.2%Q4 2020
RVMDRevolution Medicines, Inc.$231M2.94%1.47%-20.7%Q1 2020
UTHRUNITED THERAPEUTICS Corp$208M2.65%0.98%Not reportedQ1 2025
VERAVera Therapeutics, Inc.$206M2.63%6.35%+11.5%Q1 2023
CELCCelcuity Inc.$171M2.18%3.55%+133.7%Q3 2025
NBIXNeurocrine Biosciences Inc$168M2.15%1.18%Not reportedQ1 2014
IONSIonis Pharmaceuticals Inc$157M2.00%1.21%Not reportedQ4 2016
NAMSNewAmsterdam Pharma Co N.V.$146M1.87%3.64%-2.4%Q4 2022
INSPInspire Medical Systems, Inc.$139M1.77%5.27%+43.7%Q3 2018
LEGNLegend Biotech Corp$129M1.65%1.60%+100.3%Q4 2024
BKDBrookdale Senior Living Inc.$126M1.60%4.89%0.0%Q3 2015
INDVIndivior Pharmaceuticals, Inc.$122M1.55%2.72%-51.4%Q3 2024
ARWRArrowhead Pharmaceuticals, Inc.$122M1.55%1.33%+84.6%Q4 2013
LRMRLarimar Therapeutics, Inc.$117M1.49%36.84%Not reportedQ2 2020
CPRXCatalyst Pharmaceuticals, Inc.$115M1.46%4.01%-1.3%Q3 2022
AHCOAdaptHealth Corp.$114M1.46%8.47%Not reportedQ4 2019
BCRXBiocryst Pharmaceuticals Inc$112M1.43%6.73%+17.9%Q3 2013
SPRYARS Pharmaceuticals, Inc.$87.4M1.12%7.56%Not reportedQ4 2022
PHVSPharvaris N.V.$86.7M1.11%4.79%+28.0%Q1 2021
SVRASavara Inc$81.8M1.04%6.63%+70.4%Q3 2018
IDYAIDEAYA Biosciences, Inc.$74.4M0.95%2.45%Not reportedQ2 2019
CERTCertara, Inc.$68.8M0.88%4.91%+15.9%Q4 2020
BIOBio-Rad Laboratories, Inc.$68.5M0.87%0.82%Not reportedQ3 2023
ACHCAcadia Healthcare Company, Inc.$64.1M0.82%5.00%+280.2%Q4 2017
BBOTBridgeBio Oncology Therapeutics, Inc.$61.2M0.78%6.11%Not reportedQ3 2025
STOKStoke Therapeutics, Inc.$57.9M0.74%3.09%NewQ4 2025
LNTHLantheus Holdings, Inc.$55.1M0.70%1.28%Not reportedQ1 2024
GPCRStructure Therapeutics Inc.$53.4M0.68%0.36%+105.7%Q1 2023
NVSTEnvista Holdings Corp$49.5M0.63%1.39%-0.6%Q3 2024
EHABEnhabit, Inc.$43.8M0.56%9.36%Not reportedQ3 2022
KYMRKymera Therapeutics, Inc.$43.7M0.56%0.69%-1.9%Q4 2024
CDNACareDx, Inc.$41.3M0.53%4.30%Not reportedQ3 2014
IRONDisc Medicine, Inc.$40.6M0.52%1.35%-44.4%Q2 2023
SIONSionna Therapeutics, Inc.$39.9M0.51%2.17%Not reportedQ1 2025
BLTEBelite Bio, Inc$37.4M0.48%0.59%NewQ4 2025
DAWNDay One Biopharmaceuticals, Inc.$34.7M0.44%3.62%-20.9%Q2 2021
PHRPhreesia, Inc.$33.8M0.43%3.32%+79.0%Q2 2022
EMBCEmbecta Corp.$32.7M0.42%4.65%+5.0%Q4 2023
VCYTVeracyte, Inc.$30.6M0.39%0.91%Not reportedQ2 2015
BBNXBeta Bionics, Inc.$28.6M0.37%2.12%-19.7%Q1 2025
VTRVentas, Inc.$27.4M0.35%0.07%Not reportedQ2 2025
ALNYAlnylam Pharmaceuticals, Inc.$27M0.35%0.05%Not reportedQ2 2013
TNGXTango Therapeutics, Inc.$25.8M0.33%2.14%Not reportedQ3 2023
XENEXenon Pharmaceuticals Inc.$24.3M0.31%0.68%Not reportedQ2 2025
SYRESpyre Therapeutics, Inc.$23.3M0.30%0.91%+15.8%Q4 2024
FHTXFoghorn Therapeutics Inc.$19.7M0.25%6.44%+12.1%Q1 2022
Q3 2025Reported Nov 14, 2025141 positions
NUVLNuvalent, Inc.$1.56B23.75%574.91%Not reportedQ3 2021
CNCCentene Corp$323M4.93%1.84%+184.0%Q4 2013
MRUSMerus N.V.$287M4.38%4.02%-10.0%Q4 2021
VTRSViatris Inc$239M3.64%2.07%+0.3%Q4 2020
UTHRUNITED THERAPEUTICS Corp$179M2.73%0.99%-21.2%Q1 2025
RVMDRevolution Medicines, Inc.$170M2.60%1.92%+7.9%Q1 2020
INDVIndivior Pharmaceuticals, Inc.$168M2.57%5.60%-33.9%Q3 2024
NBIXNeurocrine Biosciences Inc$166M2.54%1.19%+1.4%Q1 2014
COGTCogent Biosciences, Inc.$130M1.98%6.47%+242.9%Q4 2020
IONSIonis Pharmaceuticals Inc$130M1.98%1.23%Not reportedQ4 2016
NAMSNewAmsterdam Pharma Co N.V.$121M1.85%3.77%-16.6%Q4 2022
VERAVera Therapeutics, Inc.$106M1.62%5.71%+8.8%Q1 2023
BMYBristol Myers Squibb Co$105M1.61%0.11%Not reportedQ4 2023
AHCOAdaptHealth Corp.$103M1.57%8.48%+15.9%Q4 2019
LRMRLarimar Therapeutics, Inc.$98.9M1.51%35.76%+44.2%Q2 2020
BKDBrookdale Senior Living Inc.$98.6M1.51%4.90%-24.2%Q3 2015
CPRXCatalyst Pharmaceuticals, Inc.$98M1.50%4.04%+72.8%Q3 2022
LEGNLegend Biotech Corp$96.6M1.47%0.81%Not reportedQ4 2024
BCRXBiocryst Pharmaceuticals Inc$92.4M1.41%5.78%+159.4%Q3 2013
MRKMerck & Co., Inc.$86.4M1.32%0.04%+20.1%Q2 2013
PFEPfizer Inc$84.2M1.29%0.06%-23.3%Q2 2013
CERTCertara, Inc.$82.4M1.26%4.23%+71.7%Q4 2020
INSPInspire Medical Systems, Inc.$77.7M1.19%3.61%+648.4%Q3 2018
SPRYARS Pharmaceuticals, Inc.$75.4M1.15%7.59%-22.8%Q4 2022
INSMINSMED Inc$67.8M1.04%0.22%-32.8%Q2 2013
BIOBio-Rad Laboratories, Inc.$63.4M0.97%0.82%Not reportedQ3 2023
PHVSPharvaris N.V.$60.9M0.93%4.49%+21.1%Q1 2021
IRONDisc Medicine, Inc.$60.8M0.93%2.63%Not reportedQ2 2023
IDYAIDEAYA Biosciences, Inc.$58.6M0.89%2.46%-45.0%Q2 2019
BBOTBridgeBio Oncology Therapeutics, Inc.$56.6M0.86%6.17%NewQ3 2025
NVSTEnvista Holdings Corp$46.7M0.71%1.39%+3.5%Q3 2024
PRAXPraxis Precision Medicines, Inc.$44.6M0.68%3.97%+22.4%Q4 2020
CRMDCorMedix Inc.$38.7M0.59%4.24%NewQ3 2025
EHABEnhabit, Inc.$38M0.58%9.37%-0.7%Q3 2022
EMBCEmbecta Corp.$37M0.56%4.48%-4.7%Q4 2023
CELCCelcuity Inc.$36.2M0.55%1.70%NewQ3 2025
CNMDCONMED Corp$35.8M0.55%2.46%+8.6%Q4 2023
ZBIOZenas BioPharma, Inc.$34.7M0.53%3.70%Not reportedQ3 2024
NEONeogenomics Inc$34.3M0.52%3.45%+107.1%Q2 2024
ARWRArrowhead Pharmaceuticals, Inc.$34.2M0.52%0.73%Not reportedQ4 2013
DAWNDay One Biopharmaceuticals, Inc.$33.2M0.51%4.58%+26.4%Q2 2021
KYMRKymera Therapeutics, Inc.$32.4M0.49%0.80%-12.4%Q4 2024
CDNACareDx, Inc.$31.9M0.49%4.26%Not reportedQ3 2014
ALNYAlnylam Pharmaceuticals, Inc.$31M0.47%0.05%-53.2%Q2 2013
ACHCAcadia Healthcare Company, Inc.$29.4M0.45%1.31%Not reportedQ4 2017
SIONSionna Therapeutics, Inc.$28.5M0.44%2.18%Not reportedQ1 2025
SVRASavara Inc$28.4M0.43%4.61%Not reportedQ3 2018
PHRPhreesia, Inc.$26.3M0.40%1.86%+10.1%Q2 2022
VCYTVeracyte, Inc.$24.9M0.38%0.92%+16.2%Q2 2015
VTRVentas, Inc.$24.8M0.38%0.08%Not reportedQ2 2025
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