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Commodore Capital LP

13F filer · CIK 0001831942
Reported Aug 14, 2026
Net seller this quarter
13F portfolio value$1.68BU.S. long equity reported on 13F
Positions335 new · 8 closed
Net flow last quarter-$587MBuys minus sells
Top 10 positions weight68.2%Concentration

Holdings

13F · last 4 quarters free
Scroll for earlier quarters
CompanyValue% of portfolio% of companyPOSITION CHANGE qoq %First reported
Q2 2026Reported Aug 14, 202633 positions
RLAYRelay Therapeutics, Inc.$225M13.37%5.49%-29.4%Q2 2025
ELVNEnliven Therapeutics, Inc.$166M9.90%4.47%Not reportedQ1 2023
ALKSAlkermes plc.$157M9.36%1.79%-28.6%Q2 2024
COGTCogent Biosciences, Inc.$118M7.03%1.78%+5.6%Q4 2020
AMLXAmylyx Pharmaceuticals, Inc.$101M6.04%5.07%Not reportedQ3 2025
DFTXDefinium Therapeutics, Inc.$94.1M5.60%1.49%Not reportedQ1 2026
SYRESpyre Therapeutics, Inc.$75.2M4.48%0.96%-55.7%Q3 2023
ANROAlto Neuroscience, Inc.$71.9M4.28%7.76%Not reportedQ4 2025
TNGXTango Therapeutics, Inc.$70.3M4.19%1.34%Not reportedQ2 2025
EYPTEyePoint, Inc.$65.8M3.92%5.41%+62.8%Q1 2026
TYRATyra Biosciences, Inc.$59.9M3.57%3.14%-24.2%Q1 2025
DMRADamora Therapeutics, Inc.$50.4M3.00%3.14%Not reportedQ1 2026
CLDXCelldex Therapeutics, Inc.$50.2M2.99%1.72%-49.9%Q4 2020
PHVSPharvaris N.V.$49.3M2.93%2.19%-25.7%Q4 2023
LBRXLB Pharmaceuticals Inc$48.7M2.90%5.23%Not reportedQ3 2025
ASMBAssembly Biosciences, Inc.$38.9M2.32%7.13%+41.5%Q3 2025
EDITEditas Medicine, Inc.$28.8M1.72%9.08%NewQ2 2026
KYMRKymera Therapeutics, Inc.$28.7M1.71%0.30%-66.7%Q2 2025
CATXPerspective Therapeutics, Inc.$21.6M1.29%5.55%Not reportedQ1 2024
IPSCCentury Therapeutics, Inc.$21.3M1.27%4.82%Not reportedQ1 2026
ZURAZura Bio Ltd$19.2M1.14%3.41%Not reportedQ1 2026
AVTXAvalo Therapeutics, Inc.$18.8M1.12%1.93%+110.8%Q2 2024
IFRXInflaRx N.V.$16.4M0.97%10.10%NewQ2 2026
ANTXAN2 Therapeutics, Inc.$14.2M0.85%8.08%+25.7%Q1 2026
NUVLNuvalent, Inc.$12.4M0.74%3.20%-88.0%Q4 2022
SABSSAB Biotherapeutics, Inc.$11.2M0.67%3.44%-34.8%Q4 2023
IKTInhibikase Therapeutics, Inc.$11M0.65%4.09%Not reportedQ4 2024
RLMDRelmada Therapeutics, Inc.$9.86M0.59%1.34%+124.8%Q4 2020
PEPGPepGen Inc.$8.06M0.48%6.47%Not reportedQ3 2025
RACCResearch Alliance Corp III$5.35M0.32%Not reportedNewQ2 2026
HLXCHelix Acquisition Corp. III$5.32M0.32%Not reportedNot reportedQ1 2026
LONALeonaBio, Inc.$4.27M0.25%4.93%Not reportedQ4 2025
VTGNVistagen Therapeutics, Inc.$630K0.04%6.80%Not reportedQ4 2020
Q1 2026Reported May 15, 202636 positions
RLAYRelay Therapeutics, Inc.$169M9.79%8.98%Not reportedQ2 2025
ALKSAlkermes plc.$149M8.59%2.52%+18.3%Q2 2024
ELVNEnliven Therapeutics, Inc.$128M7.43%5.38%-30.2%Q1 2023
COGTCogent Biosciences, Inc.$111M6.43%1.69%+31.5%Q4 2020
SYRESpyre Therapeutics, Inc.$96.5M5.58%2.43%-19.9%Q3 2023
TYRATyra Biosciences, Inc.$94.8M5.48%4.16%-26.7%Q1 2025
CLDXCelldex Therapeutics, Inc.$85.5M4.95%4.05%+5.1%Q4 2020
NUVLNuvalent, Inc.$85.4M4.94%26.64%+51.6%Q4 2022
AMLXAmylyx Pharmaceuticals, Inc.$78.5M4.54%5.09%Not reportedQ3 2025
KYMRKymera Therapeutics, Inc.$62.5M3.61%0.91%Not reportedQ2 2025
ANROAlto Neuroscience, Inc.$61.2M3.54%7.77%+49.4%Q4 2025
PHVSPharvaris N.V.$54.2M3.14%2.94%+1.6%Q4 2023
ERASErasca, Inc.$51.4M2.97%1.02%NewQ1 2026
DMRADamora Therapeutics, Inc.$50.2M2.91%3.22%NewQ1 2026
XENEXenon Pharmaceuticals Inc.$48M2.78%0.85%-54.2%Q4 2020
DFTXDefinium Therapeutics, Inc.$37.8M2.19%1.92%NewQ1 2026
LBRXLB Pharmaceuticals Inc$37M2.14%5.23%Not reportedQ3 2025
EYPTEyePoint, Inc.$36.4M2.11%3.39%NewQ1 2026
NRIXNurix Therapeutics, Inc.$35.3M2.04%2.20%Not reportedQ3 2024
CRVSCorvus Pharmaceuticals, Inc.$33M1.91%2.69%NewQ1 2026
ASMBAssembly Biosciences, Inc.$27.8M1.61%6.29%Not reportedQ3 2025
CATXPerspective Therapeutics, Inc.$26.4M1.53%5.56%Not reportedQ1 2024
SLNOSoleno Therapeutics Inc$21.8M1.26%1.26%-45.6%Q3 2023
OCULOcular Therapeutix, Inc$21.8M1.26%1.18%NewQ1 2026
IPSCCentury Therapeutics, Inc.$19.7M1.14%4.83%NewQ1 2026
ZURAZura Bio Ltd$19.3M1.12%3.43%NewQ1 2026
SABSSAB Biotherapeutics, Inc.$16.9M0.98%5.81%Not reportedQ4 2023
PALIPalisade Bio, Inc.$12.6M0.73%4.29%-37.3%Q4 2025
KPTIKaryopharm Therapeutics Inc.$10.9M0.63%8.65%Not reportedQ1 2022
IKTInhibikase Therapeutics, Inc.$9.07M0.52%4.09%Not reportedQ4 2024
ANTXAN2 Therapeutics, Inc.$7.98M0.46%6.49%NewQ1 2026
PEPGPepGen Inc.$7.92M0.46%6.47%+31.6%Q3 2025
AVTXAvalo Therapeutics, Inc.$7.21M0.42%1.96%Not reportedQ2 2024
HLXCHelix Acquisition Corp. III$5.08M0.29%Not reportedNewQ1 2026
LONALeonaBio, Inc.$4.77M0.28%4.94%Not reportedQ4 2025
RLMDRelmada Therapeutics, Inc.$4.41M0.26%0.60%Not reportedQ4 2020
Q4 2025Reported Feb 17, 202633 positions
RLAYRelay Therapeutics, Inc.$144M9.57%9.78%Not reportedQ2 2025
ALKSAlkermes plc.$99.3M6.61%2.14%+14.6%Q2 2024
TYRATyra Biosciences, Inc.$88.7M5.91%6.28%Not reportedQ1 2025
XENEXenon Pharmaceuticals Inc.$80.7M5.37%2.25%-33.3%Q4 2020
SYRESpyre Therapeutics, Inc.$78.2M5.21%3.05%+20.1%Q3 2023
COGTCogent Biosciences, Inc.$78M5.19%1.36%-69.7%Q4 2020
ELVNEnliven Therapeutics, Inc.$72.3M4.81%7.90%Not reportedQ1 2023
CLDXCelldex Therapeutics, Inc.$69.7M4.64%3.85%-15.3%Q4 2020
AMLXAmylyx Pharmaceuticals, Inc.$68.3M4.54%5.14%+38.6%Q3 2025
TERNTerns Pharmaceuticals, Inc.$59.6M3.97%1.31%-74.1%Q3 2022
KYMRKymera Therapeutics, Inc.$58.4M3.88%0.92%Not reportedQ2 2025
SLNOSoleno Therapeutics Inc$55.6M3.70%2.30%-11.1%Q3 2023
NUVLNuvalent, Inc.$55.3M3.68%17.58%-60.7%Q4 2022
ORKAOruka Therapeutics, Inc.$53.1M3.54%3.60%Not reportedQ3 2024
PHVSPharvaris N.V.$52.4M3.49%2.90%-21.9%Q4 2023
NRIXNurix Therapeutics, Inc.$43.2M2.87%2.23%-39.8%Q3 2024
PTGXProtagonist Therapeutics, Inc$39.3M2.62%0.72%-56.1%Q4 2020
ASMBAssembly Biosciences, Inc.$34M2.26%6.31%Not reportedQ3 2025
LBRXLB Pharmaceuticals Inc$33.4M2.22%5.93%Not reportedQ3 2025
CTMXCytomX Therapeutics, Inc.$32.8M2.18%4.52%Not reportedQ2 2025
ANROAlto Neuroscience, Inc.$32.5M2.16%5.71%NewQ4 2025
PALIPalisade Bio, Inc.$26.9M1.79%7.18%NewQ4 2025
MNMDDefinium Therapeutics, Inc.$26.8M1.78%Not reported-38.0%Q1 2024
CNTACentessa Pharmaceuticals PLC$25M1.66%0.67%-64.9%Q3 2024
PEPGPepGen Inc.$22.1M1.47%4.94%+44.2%Q3 2025
SABSSAB Biotherapeutics, Inc.$16.5M1.10%9.24%Not reportedQ4 2023
REPLReplimune Group, Inc.$13.9M0.92%1.79%NewQ4 2025
IKTInhibikase Therapeutics, Inc.$11.1M0.74%4.10%Not reportedQ4 2024
CTNMContineum Therapeutics, Inc.$9.33M0.62%3.53%NewQ4 2025
AVTXAvalo Therapeutics, Inc.$8.77M0.58%2.61%Not reportedQ2 2024
RAPTRAPT Therapeutics, Inc.$8.47M0.56%0.90%NewQ4 2025
LONALeonaBio, Inc.$3.52M0.23%4.97%NewQ4 2025
DRUGBright Minds Biosciences Inc.$1.47M0.10%0.25%-96.2%Q4 2024
Q3 2025Reported Nov 14, 202537 positions
MRUSMerus N.V.$332M16.20%4.65%Not reportedQ3 2021
NUVLNuvalent, Inc.$121M5.91%44.74%+1.8%Q4 2022
XENEXenon Pharmaceuticals Inc.$108M5.29%3.50%-10.7%Q4 2020
COGTCogent Biosciences, Inc.$104M5.08%5.19%+213.7%Q4 2020
ELVNEnliven Therapeutics, Inc.$96.1M4.69%7.92%Not reportedQ1 2023
AGIOAgios Pharmaceuticals, Inc.$93.9M4.58%4.01%+0.6%Q1 2025
ALKSAlkermes plc.$92.9M4.54%1.88%+26.4%Q2 2024
SLNOSoleno Therapeutics Inc$91.3M4.46%2.51%+121.3%Q3 2023
RLAYRelay Therapeutics, Inc.$88.7M4.33%9.85%+27.3%Q2 2025
CLDXCelldex Therapeutics, Inc.$78.3M3.82%4.56%-12.2%Q4 2020
CNTACentessa Pharmaceuticals PLC$69.1M3.37%2.12%-13.6%Q3 2024
VRDNViridian Therapeutics, Inc.\DE$69.1M3.37%3.89%-34.4%Q1 2021
PTGXProtagonist Therapeutics, Inc$68.1M3.32%1.64%-4.7%Q4 2020
PHVSPharvaris N.V.$60.3M2.95%4.45%+26.5%Q4 2023
CDTXCidara Therapeutics, Inc.$56M2.73%1.99%-50.2%Q2 2025
AMLXAmylyx Pharmaceuticals, Inc.$55.4M2.70%3.71%NewQ3 2025
TYRATyra Biosciences, Inc.$47.2M2.30%6.33%+8.9%Q1 2025
TERNTerns Pharmaceuticals, Inc.$42.8M2.09%6.51%Not reportedQ3 2022
KYMRKymera Therapeutics, Inc.$42.5M2.07%1.05%Not reportedQ2 2025
MNMDDefinium Therapeutics, Inc.$38M1.86%Not reported-35.5%Q1 2024
NRIXNurix Therapeutics, Inc.$34.9M1.71%4.92%-4.3%Q3 2024
ORKAOruka Therapeutics, Inc.$33.7M1.65%3.62%+23.5%Q3 2024
SYRESpyre Therapeutics, Inc.$33.3M1.63%3.29%Not reportedQ3 2023
DRUGBright Minds Biosciences Inc.$30.3M1.48%6.55%Not reportedQ4 2024
ASMBAssembly Biosciences, Inc.$25.6M1.25%6.32%NewQ3 2025
CTMXCytomX Therapeutics, Inc.$24.5M1.20%4.66%Not reportedQ2 2025
LBRXLB Pharmaceuticals Inc$23.7M1.16%5.93%NewQ3 2025
TNGXTango Therapeutics, Inc.$12.6M0.62%1.34%Not reportedQ2 2025
APGEApogee Therapeutics, Inc.$11.5M0.56%0.49%Not reportedQ3 2023
PEPGPepGen Inc.$10.9M0.53%7.19%NewQ3 2025
ENTAEnanta Pharmaceuticals Inc$9.58M0.47%3.74%Not reportedQ3 2022
SABSSAB Biotherapeutics, Inc.$8.85M0.43%9.27%Not reportedQ4 2023
IKTInhibikase Therapeutics, Inc.$8.74M0.43%7.22%Not reportedQ4 2024
FRNMFreenome, Inc.$7.92M0.39%8.42%Not reportedQ2 2024
AVTXAvalo Therapeutics, Inc.$6.14M0.30%2.71%Not reportedQ2 2024
VTGNVistagen Therapeutics, Inc.$5.59M0.27%5.13%Not reportedQ4 2020
CBIOCrescent Biopharma, Inc.$5.36M0.26%3.25%-0.6%Q2 2025
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