Karyopharm Therapeutics Inc.

KPTINASDAQ

$0.80-0.07 (-7.50%)as of Oct 2, 2026

Legend

Insider buy

Insider sell

Congress buy

Congress sell

Hedge Funds
bought vs soldGreener markers show more buyers; redder markers show more sellers.

Company share activityNet buybacksNo changeNet dilution

Marker size reflects transaction size.

Insider buy
Insider sell
Congress buy
Congress sell
Hedge Funds bought vs sold

Share activityNet buybacksNo changeNet dilution

Marker size reflects transaction size. Greener fund markers mean more buyers.

Insider Buy
Insider Sell
Congress Buy
Congress Sell
Hedge funds bought vs sold
BuybackNo changeNet dilution

Karyopharm Therapeutics Inc. price and activity chart data

Showing the 1Y range: Oct 2, 2025 to Oct 2, 2026. Price (-87.2%). 0 insider or congressional trades plotted in this window as 0 markers; nearby trades of the same kind are grouped.

Transactions plotted on the price chart
Date	Category	Person	Role	Action	Amount	Change in holding

Largest institutional holders

13F · Q2 2026

Fund	% of company held	Value	% of portfolio	Quarterly activity
Ra Capital Management, L.P.	8.45%	$18.7M	0.16%	Not reported
Adage Capital Partners GP, L.L.C.	6.71%	$14.9M	0.02%	Reduce 15.78%
Acorn Capital Advisors, LLC	6.69%	$14.8M	4.05%	Add 427.44%
Goldman Sachs Group Inc	6.28%	$13.9M	0.00%	Not reported
BlackRock, Inc.	6.26%	$13.9M	0.00%	Not reported
Kalehua Capital Management LLC	6.05%	$13.4M	4.27%	New Not reported
Vanguard Capital Management LLC	4.23%	$9.37M	0.00%	Not reported
Catalio Capital Management, LP	4.15%	$9.19M	1.73%	Add 4.81%
Avidity Partners Management LP	4.08%	$9.03M	1.45%	Reduce 0.32%
T. Rowe Price Investment Management, Inc.	3.47%	$7.68M	0.01%	Reduce 49.01%
Two Sigma Investments, LP	3.07%	$6.79M	0.00%	Not reported
NEA Management Company, LLC	2.54%	$5.64M	0.35%	New Not reported
Geode Capital Management, LLC	2.34%	$5.19M	0.00%	Not reported
Ghisallo Capital Management LLC	2.20%	$4.89M	0.10%	Not reported
Soleus Capital Management, L.P.	1.94%	$4.3M	0.15%	Not reported
UBS Group AG	1.56%	$3.45M	0.00%	Not reported
State Street Corp	1.44%	$3.18M	0.00%	Not reported
Affinity Asset Advisors, LLC	1.38%	$3.05M	0.14%	Reduce 37.50%
Brevan Howard Capital Management LP	1.37%	$3.03M	0.02%	Not reported
Millennium Management LLC	1.35%	$2.99M	0.00%	Not reported
Boxer Capital Management, LLC	1.33%	$2.96M	0.22%	Not reported
Davidson Kempner Capital Management LP	1.32%	$2.93M	0.03%	Not reported
Acadian Asset Management LLC	1.32%	$2.92M	0.00%	Not reported
Silverarc Capital Management, LLC	1.31%	$2.91M	0.30%	New Not reported
Eversept Partners, LP	1.22%	$2.7M	0.14%	Not reported
JPMorgan Chase & Co	0.92%	$2.09M	0.00%	Not reported
Morgan Stanley	0.89%	$1.98M	0.00%	Not reported
Trexquant Investment LP	0.83%	$1.84M	0.01%	Not reported
BNP Paribas Financial Markets	0.83%	$1.84M	0.00%	Not reported
Barclays PLC	0.73%	$1.62M	0.00%	Not reported
Northern Trust Corp	0.71%	$1.56M	0.00%	Not reported
Vanguard Fiduciary Trust Co	0.64%	$1.42M	0.00%	Not reported
Vanguard Portfolio Management LLC	0.59%	$1.32M	0.00%	Not reported
Marshall Wace, LLP	0.57%	$1.25M	0.00%	Not reported
Renaissance Technologies LLC	0.48%	$1.06M	0.00%	Not reported
C WorldWide Group Holding A/S	0.44%	$977K	0.02%	Not reported
Jump Financial, LLC	0.41%	$918K	0.01%	Not reported
Invesco Ltd.	0.40%	$882K	0.00%	Not reported
Bridgeway Capital Management, LLC	0.32%	$702K	0.01%	Not reported
J. Goldman & Co LP	0.30%	$659K	0.02%	New Not reported
Squarepoint Ops LLC	0.28%	$623K	0.00%	Not reported
Charles Schwab Investment Management Inc	0.27%	$605K	0.00%	Not reported
Royal Bank of Canada	0.27%	$590K	0.00%	Not reported
Bank of New York Mellon Corp	0.25%	$559K	0.00%	Not reported
Susquehanna Portfolio Strategies, LLC	0.24%	$533K	0.01%	Add 118.00%
XTX Topco Ltd	0.23%	$520K	0.01%	Not reported
Citadel Advisors LLC	0.23%	$509K	0.00%	Not reported
Bank of America Corp	0.22%	$488K	0.00%	Not reported
Birchview Capital, LP	0.19%	$420K	0.20%	Reduce 48.84%
Citigroup Inc	0.17%	$370K	0.00%	Not reported

50 of 92 holders

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