| Ra Capital Management, L.P. | Sell 100% | -$38.8M | $0 | 0.00% | Aug 14, 2026 |
| Jennison Associates LLC | Sell 100% | -$27.2M | $0 | 0.00% | Aug 3, 2026 |
| Polar Capital Holdings Plc | Sell 100% | -$23.9M | $0 | 0.00% | Aug 14, 2026 |
| Cormorant Asset Management, LP | Reduce 44.87% | -$21.9M | $26.9M | 1.38% | Aug 14, 2026 |
| Deep Track Capital, LP | New Buy | +$18.8M | $18.8M | 0.27% | Aug 14, 2026 |
| First Turn Management, LLC | Sell 100% | -$11.5M | $0 | 0.00% | Aug 14, 2026 |
| Paradigm Biocapital Advisors LP | Added 8.10% | +$8.13M | $108M | 2.03% | Aug 14, 2026 |
| Readystate Asset Management LP | New Buy | +$7.43M | $7.43M | 0.25% | Aug 14, 2026 |
| Defilade Capital Management, L.P. | Reduce 38.54% | -$7.25M | $11.6M | 1.55% | Aug 14, 2026 |
| Jones Hill Capital LP | New Buy | +$7.18M | $7.18M | 1.53% | Aug 13, 2026 |
| Bain Capital Life Sciences Investors, LLC | Reduce 5.19% | -$4.85M | $88.6M | 5.27% | Aug 14, 2026 |
| Kingdon Capital Management, L.L.C. | Added 40.35% | +$4.32M | $15M | 1.54% | Aug 14, 2026 |
| Adage Capital Partners GP, L.L.C. | Sell 100% | -$4.1M | $0 | 0.00% | Aug 14, 2026 |
| Pictet Asset Management Holding SA | Sell 100% | -$3.24M | $0 | 0.00% | Jul 30, 2026 |
| Ikarian Capital, LLC | Reduce 35.94% | -$2.69M | $4.79M | 0.52% | Aug 14, 2026 |
| Burkehill Global Management, LP | Sell 100% | -$1.86M | $0 | 0.00% | Aug 14, 2026 |
| Wellington Management Group LLP | Reduce 20.80% | -$1.73M | $6.59M | 0.00% | Aug 14, 2026 |
| Ensign Peak Advisors, Inc | Sell 100% | -$1.44M | $0 | 0.00% | Aug 14, 2026 |
| Schroder Investment Management Group | New Buy | +$1.39M | $1.39M | 0.00% | Aug 13, 2026 |
| Siren, L.L.C. | Added 2.10% | +$1.25M | $60.8M | 1.23% | Aug 13, 2026 |
| Pier Capital, LLC | Added 62.15% | +$1.06M | $2.76M | 0.37% | Aug 5, 2026 |
| Rock Springs Capital Management LP | Added 38.03% | +$811K | $2.94M | 0.14% | Aug 14, 2026 |
| Hennion & Walsh Asset Management, Inc. | Reduce 12.73% | -$767K | $5.26M | 0.15% | Jul 8, 2026 |
| Rafferty Asset Management, LLC | Reduce 42.58% | -$701K | $945K | 0.00% | Aug 14, 2026 |
| Susquehanna Fundamental Investments, LLC | New Buy | +$690K | $690K | 0.01% | Aug 14, 2026 |
| Integral Health Asset Management, LLC | Reduce 33.33% | -$626K | $1.25M | 0.05% | Aug 14, 2026 |
| Fideuram - Intesa Sanpaolo Private Banking S.P.A. | Added 38.54% | +$563K | $2.02M | 0.06% | Jul 23, 2026 |
| HighVista Strategies LLC | Added 36.20% | +$533K | $2M | 0.46% | Aug 14, 2026 |
| Erste Asset Management GmbH | Sell 100% | -$510K | $0 | 0.00% | Jul 28, 2026 |
| Quantinno Capital Management LP | Reduce 41.39% | -$494K | $699K | 0.00% | Aug 13, 2026 |
| Susquehanna Portfolio Strategies, LLC | Added 29.71% | +$423K | $1.85M | 0.03% | Aug 14, 2026 |
| Seven Fleet Capital Management LP | New Buy | +$394K | $394K | 0.07% | Aug 17, 2026 |
| Virtus Investment Advisers, LLC | Added 301.82% | +$311K | $415K | 0.10% | Aug 11, 2026 |
| Alps Advisors Inc | Added 38.44% | +$308K | $1.11M | 0.01% | Jul 29, 2026 |
| Profund Advisors LLC | Reduce 34.52% | -$253K | $480K | 0.01% | Aug 11, 2026 |
| Birchview Capital, LP | Reduce 9.13% | -$250K | $2.49M | 1.16% | Aug 14, 2026 |
| Graham Capital Management, L.P. | Sell 100% | -$249K | $0 | 0.00% | Aug 14, 2026 |
| Bellevue Group AG | Sell 100% | -$245K | $0 | 0.00% | Aug 14, 2026 |
| Jain Global LLC | New Buy | +$242K | $242K | 0.00% | Aug 14, 2026 |
| PDT Partners, LLC | Sell 100% | -$228K | $0 | 0.00% | Aug 14, 2026 |
| Axq Capital, LP | Sell 100% | -$218K | $0 | 0.00% | Aug 6, 2026 |
| EntryPoint Capital, LLC | New Buy | +$181K | $181K | 0.04% | Aug 13, 2026 |
| VANGUARD ASSET MANAGEMENT, Ltd | Added 55.63% | +$173K | $483K | 0.00% | Aug 13, 2026 |
| Conway Capital Management, Inc. | Sell 100% | -$149K | $0 | 0.00% | Aug 7, 2026 |
| Aristotle Atlantic Partners, LLC | Added 46.31% | +$145K | $457K | 0.02% | Aug 14, 2026 |
| Canada Pension Plan Investment Board | New Buy | +$144K | $144K | 0.00% | Aug 14, 2026 |
| Vestal Point Capital, LP | Reduce 2.33% | -$125K | $5.24M | 0.12% | Aug 14, 2026 |
| Nomura Holdings Inc | Reduce 19.31% | -$101K | $424K | 0.00% | Aug 14, 2026 |
| E Fund Management Co., Ltd. | Reduce 35.59% | -$73.6K | $133K | 0.00% | Aug 11, 2026 |
| Tidal Investments LLC | Reduce 6.33% | -$67.5K | $998K | 0.00% | Aug 13, 2026 |
| State of New Jersey Common Pension Fund D | Added 31.07% | +$50.1K | $212K | 0.00% | Aug 4, 2026 |
| Jefferies Financial Group Inc. | Added 57.14% | +$50K | $138K | 0.00% | Aug 17, 2026 |
| KLP Kapitalforvaltning As | Added 43.37% | +$45K | $149K | 0.00% | Aug 12, 2026 |
| Fisher Asset Management, LLC | Reduce 1.01% | -$37.9K | $3.71M | 0.00% | Aug 4, 2026 |
| Massachusetts Financial Services Co | Reduce 3.83% | -$22.5K | $566K | 0.00% | Aug 3, 2026 |
| KBC Group NV | Sell 100% | -$17K | $0 | 0.00% | Aug 5, 2026 |
| Pacer Advisors, Inc. | New Buy | +$16K | $16K | 0.00% | Aug 13, 2026 |
| Tema ETFs LLC | Added 0.65% | +$6.46K | $998K | 0.03% | Jul 10, 2026 |
| China Universal Asset Management Co., Ltd. | Reduce 2.28% | -$4.05K | $174K | 0.01% | Jul 24, 2026 |
| J.Safra Asset Management Corp | Added 104.76% | +$3.58K | $6.99K | 0.00% | Aug 6, 2026 |
| Versant Capital Management, Inc | Reduce 13.13% | -$2.26K | $15K | 0.00% | Jul 2, 2026 |
| Quarry LP | New Buy | +$1.39K | $1.39K | 0.00% | Aug 14, 2026 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | Added 12.54% | +$1.03K | $9.21K | 0.00% | Aug 13, 2026 |
| Optimize Financial Inc. | Reduce 0.35% | -$888 | $256K | 0.09% | Aug 27, 2026 |
| Ares Financial Consulting, LLC | New Buy | +$300 | $300 | 0.00% | Jul 9, 2026 |
| Bare Financial Services, Inc | Sell 100% | -$298 | $0 | 0.00% | Jul 27, 2026 |
| Axiom Investment Management LLC | New Buy | +$125 | $125 | 0.00% | Jul 31, 2026 |
