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Septerna, Inc. hedge fund holdings

SEPNNASDAQ
$37.87+0.16 (+0.42% today)

Every quarter, large institutional investment managers with over $100M in U.S.-listed assets under management disclose their U.S. equity holdings through 13F filings. Read together, those filings show which businesses professional capital is moving into and out of.

Price vs funds buying and selling

SEPN · close · 13FReported Aug 14, 2026

Price vs funds buying and selling data

Showing the 1Y range: Oct 6, 2025 to Oct 5, 2026. Price (+82.1%). 0 fund reports plotted in this window as 0 markers; nearby trades of the same kind are grouped.

Transactions plotted on the price chart
DateCategoryPersonRoleActionAmountChange in holding
Funds buying · new + increased
Funds selling · reduced + closed
Net buyers vs sellers
Buying = new + increased; selling = reduced + closed. Counts exclude position changes under 5% of the fund's holding last quarter.

Price and fund activity data

Quarterly 13F fund buying and selling activity
QuarterFunds buyingFunds sellingBoughtSoldFilersReported
Q2 20255321$42.5M$51.8M86Aug 14, 2025
Q3 20253130$33.6M$33.1M74Nov 14, 2025
Q4 20255520$123M$98.9M118Feb 14, 2026
Q1 20265544$71.9M$64.9M123May 15, 2026
Q2 20267136$118M$89.5M142Aug 14, 2026

Quarterly action breakdown

Q2 2026
142 filers
New position
35
$45.7M+1.36M sh
Increased
36
$72.3M+2.16M sh
Reduced
22
-$18.5M-552K sh
Out / sold
14
-$71M-2.12M sh
Last 4 quarters · free
Reported Aug 14, 2026
FundActionChange in dollarValue% of portfolioReported
BVF IncSell 100%-$32.5M$00.00%Aug 14, 2026
Loomis Sayles & Co L PNew Buy+$20.9M$20.9M0.03%Aug 14, 2026
Venrock Adviser, LLCSell 100%-$12.2M$00.00%Aug 14, 2026
Catalio Capital Management, LPAdded 82.14%+$8.1M$18M3.37%Aug 14, 2026
First Light Asset Management, LLCAdded 31.44%+$7.72M$32.3M1.96%Aug 14, 2026
Longaeva Partners L.P.Added 299.87%+$7.49M$9.99M0.22%Aug 14, 2026
ADAR1 Capital Management, LLCReduce 13.68%-$4.99M$31.5M1.44%Aug 14, 2026
Primecap Management CoAdded 11.30%+$3.97M$39.1M0.02%Aug 14, 2026
Siren, L.L.C.Reduce 5.00%-$3.35M$63.6M1.29%Aug 13, 2026
Checkpoint Capital L.P.Sell 100%-$2.41M$00.00%Aug 14, 2026
Elmind Capital, LPNew Buy+$1.66M$1.66M0.42%Aug 14, 2026
Voleon Capital Management LPNew Buy+$1.49M$1.49M0.03%Aug 14, 2026
Hussman Strategic Advisors, Inc.Reduce 40.00%-$1.41M$2.11M0.49%Aug 3, 2026
Driehaus Capital Management LLCAdded 0.85%+$1.26M$148M0.86%Aug 14, 2026
HighVista Strategies LLCNew Buy+$982K$982K0.22%Aug 14, 2026
Fox Run Management, L.L.C.New Buy+$738K$738K0.12%Aug 4, 2026
Fred Alger Management, LLCNew Buy+$702K$702K0.00%Aug 14, 2026
Adage Capital Partners GP, L.L.C.Sell 100%-$577K$00.00%Aug 14, 2026
VARCOV Co.Sell 100%-$403K$00.00%Aug 14, 2026
Numerai GP LLCSell 100%-$362K$00.00%Aug 14, 2026
Gotham Asset Management, LLCNew Buy+$312K$312K0.00%Aug 14, 2026
EntryPoint Capital, LLCSell 100%-$307K$00.00%Aug 13, 2026
Canada Pension Plan Investment BoardNew Buy+$298K$298K0.00%Aug 14, 2026
Seven Fleet Capital Management LPSell 100%-$275K$00.00%Aug 17, 2026
Quantinno Capital Management LPNew Buy+$245K$245K0.00%Aug 13, 2026
Chung Wu Investment Group, LLCNew Buy+$161K$161K0.11%Jul 31, 2026
Virtus Investment Advisers, LLCReduce 15.09%-$54.2K$305K0.07%Aug 11, 2026
China Universal Asset Management Co., Ltd.Reduce 9.81%-$39.3K$361K0.02%Jul 24, 2026
Amova Asset Management Americas, Inc.New Buy+$16.9K$16.9K0.00%Aug 13, 2026
Massachusetts Financial Services CoReduce 3.85%-$13.4K$334K0.00%Aug 3, 2026
Diadema Partners LPSell 100%-$4.85K$00.00%Aug 14, 2026
Aster Capital Management (DIFC) LtdNew Buy+$3.42K$3.42K0.00%Aug 14, 2026
MassMutual Private Wealth & Trust, FSBReduce 22.96%-$1.04K$3.48K0.00%Jul 2, 2026
Silver Grove Financial Group, Inc.New Buy+$33$330.00%Aug 13, 2026

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