| T. Rowe Price Investment Management, Inc. | Added 862.54% | +$70.8M | $79M | 0.05% | Aug 14, 2026 |
| Lynx1 Capital Management LP | Reduce 15.22% | -$23.7M | $132M | 15.27% | Aug 13, 2026 |
| EcoR1 Capital, LLC | Added 635.00% | +$20.8M | $24M | 1.17% | Aug 14, 2026 |
| Wellington Management Group LLP | Added 13.68% | +$13.9M | $115M | 0.02% | Aug 14, 2026 |
| First Trust Advisors LP | Added 200.33% | +$10.7M | $16.1M | 0.01% | Aug 11, 2026 |
| Polar Capital Holdings Plc | Reduce 26.38% | -$9.78M | $27.3M | 0.06% | Aug 14, 2026 |
| Tang Capital Management LLC | Reduce 40.00% | -$6.54M | $9.82M | 0.45% | Aug 14, 2026 |
| Troluce Capital Advisors LLC | Reduce 23.96% | -$5.12M | $16.2M | 1.67% | Aug 14, 2026 |
| Susquehanna Portfolio Strategies, LLC | Reduce 92.64% | -$3.61M | $287K | 0.00% | Aug 14, 2026 |
| Quantedge Capital Pte Ltd | Sell 100% | -$2.56M | $0 | 0.00% | Aug 6, 2026 |
| Harvest Investment Services, LLC | Sell 100% | -$2.05M | $0 | 0.00% | Aug 14, 2026 |
| Baillie Gifford & Co | Reduce 10.07% | -$1.89M | $16.9M | 0.02% | Aug 6, 2026 |
| Privium Fund Management B.V. | Sell 100% | -$1.63M | $0 | 0.00% | Aug 7, 2026 |
| MPM Bioimpact LLC | Reduce 5.70% | -$1.43M | $23.7M | 1.44% | Aug 14, 2026 |
| Hussman Strategic Advisors, Inc. | Reduce 50.00% | -$1.37M | $1.37M | 0.32% | Aug 3, 2026 |
| Quantinno Capital Management LP | Added 410.88% | +$1.31M | $1.63M | 0.00% | Aug 13, 2026 |
| Artisan Partners Limited Partnership | Added 12.57% | +$1.3M | $11.6M | 0.02% | Aug 13, 2026 |
| Birchview Capital, LP | Reduce 15.19% | -$1.04M | $5.83M | 2.73% | Aug 14, 2026 |
| Generali Investments, Management Co LLC | Added 379.59% | +$858K | $1.08M | 0.24% | Jul 10, 2026 |
| Canada Pension Plan Investment Board | Sell 100% | -$853K | $0 | 0.00% | Aug 14, 2026 |
| Parkman Healthcare Partners LLC | Added 5.62% | +$619K | $11.6M | 1.19% | Aug 14, 2026 |
| Rhenman & Partners Asset Management AB | Reduce 22.29% | -$605K | $2.11M | 0.20% | Aug 13, 2026 |
| Erste Asset Management GmbH | Reduce 3.95% | -$571K | $13.9M | 0.11% | Jul 28, 2026 |
| Alps Advisors Inc | Added 35.51% | +$540K | $2.06M | 0.01% | Jul 29, 2026 |
| Jefferies Financial Group Inc. | Sell 100% | -$531K | $0 | 0.00% | Aug 17, 2026 |
| Rafferty Asset Management, LLC | Reduce 26.97% | -$529K | $1.43M | 0.00% | Aug 14, 2026 |
| Campbell & CO Investment Adviser LLC | Sell 100% | -$490K | $0 | 0.00% | Aug 3, 2026 |
| Massachusetts Financial Services Co | Reduce 52.18% | -$387K | $354K | 0.00% | Aug 3, 2026 |
| OMERS ADMINISTRATION Corp | Reduce 27.71% | -$376K | $982K | 0.01% | Aug 13, 2026 |
| Jain Global LLC | New Buy | +$356K | $356K | 0.00% | Aug 14, 2026 |
| Aviva PLC | Sell 100% | -$302K | $0 | 0.00% | Aug 13, 2026 |
| Yorktown Management & Research Co Inc | New Buy | +$299K | $299K | 0.18% | Jul 23, 2026 |
| Farallon Capital Management, L.L.C. | Sell 100% | -$293K | $0 | 0.00% | Aug 14, 2026 |
| Inspire Advisors, LLC | New Buy | +$276K | $276K | 0.02% | Aug 13, 2026 |
| Seven Fleet Capital Management LP | New Buy | +$255K | $255K | 0.04% | Aug 17, 2026 |
| Swiss Life Asset Management Ltd | Sell 100% | -$213K | $0 | 0.00% | Jul 29, 2026 |
| CANADA LIFE ASSURANCE Co | Added 33.81% | +$208K | $824K | 0.00% | Aug 13, 2026 |
| Harbor Capital Advisors, Inc. | Added 47.78% | +$170K | $526K | 0.04% | Aug 7, 2026 |
| China Universal Asset Management Co., Ltd. | Reduce 33.19% | -$164K | $331K | 0.02% | Jul 24, 2026 |
| Profund Advisors LLC | Reduce 16.93% | -$149K | $733K | 0.02% | Aug 11, 2026 |
| Virtus Investment Advisers, LLC | Added 30.35% | +$83.6K | $359K | 0.08% | Aug 11, 2026 |
| State of New Jersey Common Pension Fund D | Reduce 12.51% | -$56K | $391K | 0.00% | Aug 4, 2026 |
| Tidal Investments LLC | Added 16.12% | +$45.1K | $324K | 0.00% | Aug 13, 2026 |
| Tema ETFs LLC | Added 16.12% | +$45.1K | $324K | 0.01% | Jul 10, 2026 |
| E Fund Management Co., Ltd. | Reduce 18.09% | -$44.6K | $202K | 0.00% | Aug 11, 2026 |
| HighVista Strategies LLC | Reduce 2.08% | -$42.6K | $2.01M | 0.46% | Aug 14, 2026 |
| Pacer Advisors, Inc. | New Buy | +$24K | $24K | 0.00% | Aug 13, 2026 |
| Quarry LP | New Buy | +$15.6K | $15.6K | 0.00% | Aug 14, 2026 |
| Gilder Gagnon Howe & Co LLC | Added 0.39% | +$14.3K | $3.7M | 0.04% | Aug 14, 2026 |
| Versant Capital Management, Inc | Added 22.55% | +$11.7K | $63.8K | 0.01% | Jul 2, 2026 |
| Cim, LLC | Added 2.31% | +$10.7K | $476K | 0.06% | Aug 13, 2026 |
| LRI Investments, LLC | Sell 100% | -$4.75K | $0 | 0.00% | Jul 14, 2026 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | Reduce 14.51% | -$3.08K | $18.1K | 0.00% | Aug 13, 2026 |
| Cresset Asset Management, LLC | Reduce 0.34% | -$2.72K | $799K | 0.00% | Aug 14, 2026 |
| Kemnay Advisory Services Inc. | Added 15.29% | +$2.36K | $17.8K | 0.00% | Aug 14, 2026 |
| J.Safra Asset Management Corp | Reduce 17.39% | -$1.7K | $8.08K | 0.00% | Aug 6, 2026 |
| Rachor Investment Advisory Services, LLC | Sell 100% | -$1.21K | $0 | 0.00% | Jul 16, 2026 |
| Strengthening Families & Communities, LLC | New Buy | +$654 | $654 | 0.00% | Aug 11, 2026 |
| Twin Peaks Wealth Advisors, LLC | Sell 100% | -$98 | $0 | 0.00% | Aug 13, 2026 |
| Keating Financial Advisory Services, Inc. | Sell 100% | -$33 | $0 | 0.00% | Aug 11, 2026 |
| Dorsey & Whitney Trust CO LLC | Added 0.01% | +$33 | $354K | 0.02% | Aug 14, 2026 |
