| Paradigm Biocapital Advisors LP | Sell 100% | -$30.6M | $0 | 0.00% | Aug 14, 2026 |
| J. Goldman & Co LP | Reduce 77.34% | -$26.7M | $7.83M | 0.20% | Aug 14, 2026 |
| Silverarc Capital Management, LLC | Reduce 13.38% | -$7.4M | $47.9M | 4.98% | Aug 13, 2026 |
| TCG Crossover Management, LLC | Sell 100% | -$7.29M | $0 | 0.00% | Aug 14, 2026 |
| Superstring Capital Management LP | Reduce 50.61% | -$7.21M | $7.04M | 4.45% | Aug 14, 2026 |
| Frontier Capital Management Co LLC | Added 14.80% | +$7.16M | $55.5M | 0.52% | Aug 14, 2026 |
| Kynam Capital Management, LP | Added 8.31% | +$6.87M | $89.6M | 4.95% | Aug 14, 2026 |
| Tang Capital Management LLC | Sell 100% | -$6.29M | $0 | 0.00% | Aug 14, 2026 |
| ADAR1 Capital Management, LLC | Reduce 36.18% | -$5.26M | $9.29M | 0.43% | Aug 14, 2026 |
| Ally Bridge Group (NY) LLC | Reduce 65.77% | -$4.89M | $2.55M | 2.25% | Aug 14, 2026 |
| Voloridge Investment Management, LLC | Reduce 51.81% | -$4.4M | $4.09M | 0.02% | Aug 14, 2026 |
| Parkman Healthcare Partners LLC | Reduce 36.70% | -$3.71M | $6.41M | 0.66% | Aug 14, 2026 |
| Elmind Capital, LP | Reduce 45.45% | -$3.68M | $4.42M | 1.11% | Aug 14, 2026 |
| Hennion & Walsh Asset Management, Inc. | Added 50.78% | +$3.43M | $10.2M | 0.29% | Jul 8, 2026 |
| Vestal Point Capital, LP | Sell 100% | -$2.5M | $0 | 0.00% | Aug 14, 2026 |
| Polen Capital Management LLC | New Buy | +$1.09M | $1.09M | 0.01% | Aug 4, 2026 |
| Privium Fund Management B.V. | Reduce 11.81% | -$1.03M | $7.73M | 1.42% | Aug 7, 2026 |
| Fox Run Management, L.L.C. | Reduce 69.00% | -$652K | $293K | 0.05% | Aug 4, 2026 |
| Capital Fund Management S.A. | New Buy | +$647K | $647K | 0.00% | Aug 13, 2026 |
| Bender Robert & Associates | Sell 100% | -$624K | $0 | 0.00% | Jul 30, 2026 |
| Birchview Capital, LP | New Buy | +$607K | $607K | 0.28% | Aug 14, 2026 |
| Diadema Partners LP | Reduce 69.18% | -$589K | $263K | 0.03% | Aug 14, 2026 |
| Wellington Management Group LLP | Added 15.11% | +$557K | $4.25M | 0.00% | Aug 14, 2026 |
| Rice Hall James & Associates, LLC | Added 5.18% | +$545K | $11.1M | 0.54% | Aug 7, 2026 |
| Jackson Creek Investment Advisors LLC | New Buy | +$540K | $540K | 0.18% | Aug 10, 2026 |
| ARK Investment Management LLC | Reduce 12.15% | -$517K | $3.74M | 0.02% | Aug 14, 2026 |
| Main Street Financial Solutions, LLC | Reduce 60.98% | -$471K | $301K | 0.02% | Aug 7, 2026 |
| Meitav Investment House Ltd | Sell 100% | -$400K | $0 | 0.00% | Jul 20, 2026 |
| Kranot Hishtalmut Le Morim Tichoniim Havera Menahelet LTD | Sell 100% | -$392K | $0 | 0.00% | Aug 5, 2026 |
| MPM Bioimpact LLC | Reduce 1.10% | -$382K | $34.3M | 2.09% | Aug 14, 2026 |
| Opaleye Management Inc. | Added 0.70% | +$368K | $53M | 4.80% | Aug 14, 2026 |
| Cresset Asset Management, LLC | New Buy | +$367K | $367K | 0.00% | Aug 14, 2026 |
| Baader Bank Aktiengesellschaft | New Buy | +$294K | $294K | 0.02% | Jul 23, 2026 |
| Debussy Capital Management LP | Sell 100% | -$282K | $0 | Not reported | Aug 14, 2026 |
| Kathmere Capital Management, LLC | New Buy | +$271K | $271K | 0.01% | Jul 29, 2026 |
| Pictet Asset Management Holding SA | New Buy | +$258K | $258K | 0.00% | Jul 30, 2026 |
| Jain Global LLC | New Buy | +$254K | $254K | 0.00% | Aug 14, 2026 |
| MML Investors Services, LLC | Reduce 31.14% | -$238K | $527K | 0.00% | Aug 7, 2026 |
| Brookstone Capital Management | New Buy | +$221K | $221K | 0.00% | Jul 15, 2026 |
| Farallon Capital Management, L.L.C. | Sell 100% | -$198K | $0 | 0.00% | Aug 14, 2026 |
| KLP Kapitalforvaltning As | Reduce 28.67% | -$151K | $375K | 0.00% | Aug 12, 2026 |
| Persistent Asset Partners Ltd | Reduce 69.27% | -$148K | $65.9K | 0.02% | Aug 7, 2026 |
| Oak Ridge Investments LLC | Added 2.53% | +$80.5K | $3.26M | 0.18% | Jul 21, 2026 |
| Shikiar Asset Management Inc | Reduce 18.60% | -$73.6K | $322K | 0.08% | Jul 21, 2026 |
| Quantinno Capital Management LP | Reduce 9.54% | -$70.8K | $672K | 0.00% | Aug 13, 2026 |
| HighVista Strategies LLC | Reduce 5.82% | -$56.7K | $919K | 0.21% | Aug 14, 2026 |
| Tidal Investments LLC | Reduce 1.08% | -$40.9K | $3.75M | 0.01% | Aug 13, 2026 |
| State of New Jersey Common Pension Fund D | Reduce 6.30% | -$31.1K | $463K | 0.00% | Aug 4, 2026 |
| DNB Asset Management AS | Reduce 4.22% | -$20.9K | $475K | 0.00% | Aug 11, 2026 |
| China Universal Asset Management Co., Ltd. | Reduce 6.66% | -$20.4K | $285K | 0.02% | Jul 24, 2026 |
| Sound Income Strategies, LLC | Sell 100% | -$7.35K | $0 | 0.00% | Jul 20, 2026 |
| Twin Peaks Wealth Advisors, LLC | Sell 100% | -$2.16K | $0 | 0.00% | Aug 13, 2026 |
| Quarry LP | New Buy | +$1.33K | $1.33K | 0.00% | Aug 14, 2026 |
| Silver Grove Financial Group, Inc. | New Buy | +$147 | $147 | 0.00% | Aug 13, 2026 |
| Keating Financial Advisory Services, Inc. | New Buy | +$74 | $74 | 0.00% | Aug 11, 2026 |
