| Kynam Capital Management, LP | Added 175.61% | +$75.5M | $119M | 6.55% | Aug 14, 2026 |
| Paradigm Biocapital Advisors LP | Added 113.53% | +$65.7M | $124M | 2.31% | Aug 14, 2026 |
| Deep Track Capital, LP | Added 157.74% | +$40.4M | $66M | 0.96% | Aug 14, 2026 |
| Caligan Partners LP | New Buy | +$40.3M | $40.3M | 1.90% | Aug 14, 2026 |
| Fairmount Funds Management LLC | Added 30.05% | +$21.6M | $93.5M | 6.18% | Aug 14, 2026 |
| Adage Capital Partners GP, L.L.C. | Sell 100% | -$19M | $0 | 0.00% | Aug 14, 2026 |
| Avoro Capital Advisors LLC | Added 66.67% | +$18.4M | $45.9M | 0.41% | Aug 14, 2026 |
| Loomis Sayles & Co L P | Sell 100% | -$18.1M | $0 | 0.00% | Aug 14, 2026 |
| Parkman Healthcare Partners LLC | Added 146.91% | +$15.1M | $25.3M | 2.59% | Aug 14, 2026 |
| First Turn Management, LLC | Added 83.25% | +$13.9M | $30.7M | 3.28% | Aug 14, 2026 |
| MPM Bioimpact LLC | Sell 100% | -$12.7M | $0 | 0.00% | Aug 14, 2026 |
| Venrock Adviser, LLC | Reduce 16.09% | -$11.5M | $59.8M | 1.81% | Aug 14, 2026 |
| Perceptive Advisors LLC | Reduce 50.29% | -$10.8M | $10.7M | 0.16% | Aug 14, 2026 |
| Emerald Advisers, LLC | New Buy | +$9.87M | $9.87M | 0.23% | Aug 5, 2026 |
| Elmind Capital, LP | Added 84.12% | +$8.27M | $18.1M | 4.55% | Aug 14, 2026 |
| Ikarian Capital, LLC | New Buy | +$7.81M | $7.81M | 0.84% | Aug 14, 2026 |
| Baker Bros. Advisors LP | Added 20.86% | +$7.56M | $43.8M | 0.22% | Aug 14, 2026 |
| Emerald Mutual Fund Advisers Trust | New Buy | +$7.27M | $7.27M | 0.26% | Aug 5, 2026 |
| ADAR1 Capital Management, LLC | Sell 100% | -$5.95M | $0 | 0.00% | Aug 14, 2026 |
| Davern Capital Partners, LP | Sell 100% | -$5.92M | $0 | 0.00% | Aug 13, 2026 |
| Pictet Asset Management Holding SA | Reduce 96.43% | -$5.56M | $206K | 0.00% | Jul 30, 2026 |
| Rice Hall James & Associates, LLC | Added 30.86% | +$5.09M | $21.6M | 1.05% | Aug 7, 2026 |
| Rosalind Advisors, Inc. | Sell 100% | -$4.9M | $0 | 0.00% | Aug 14, 2026 |
| Propel Bio Management, LLC | Sell 100% | -$4.09M | $0 | 0.00% | Aug 13, 2026 |
| Capital Fund Management S.A. | New Buy | +$3.63M | $3.63M | 0.02% | Aug 13, 2026 |
| Yiheng Capital Management, L.P. | Added 91.85% | +$3.52M | $7.36M | 2.53% | Aug 14, 2026 |
| Vivo Capital, LLC | Sell 100% | -$3.25M | $0 | 0.00% | Aug 14, 2026 |
| Voleon Capital Management LP | Reduce 63.82% | -$3.16M | $1.79M | 0.03% | Aug 14, 2026 |
| Frontier Capital Management Co LLC | Sell 100% | -$3.1M | $0 | 0.00% | Aug 14, 2026 |
| SEB Asset Management AB | Sell 100% | -$3.07M | $0 | 0.00% | Aug 4, 2026 |
| Novo Holdings A/S | Added 6.75% | +$2.48M | $39.2M | 2.28% | Aug 14, 2026 |
| F/m Investments LLC | New Buy | +$2.48M | $2.48M | 0.13% | Aug 5, 2026 |
| Nicholas Investment Partners, LP | Sell 100% | -$2.43M | $0 | 0.00% | Aug 14, 2026 |
| First Trust Advisors LP | Reduce 39.90% | -$2.21M | $3.33M | 0.00% | Aug 11, 2026 |
| Lighthouse Investment Partners, LLC | New Buy | +$2.2M | $2.2M | 0.06% | Aug 14, 2026 |
| Eversept Partners, LP | Added 16.53% | +$2.17M | $15.3M | 0.79% | Aug 14, 2026 |
| Moody Aldrich Partners LLC | Sell 100% | -$1.86M | $0 | 0.00% | Jul 15, 2026 |
| Diadema Partners LP | New Buy | +$1.84M | $1.84M | 0.23% | Aug 14, 2026 |
| Velan Capital Investment Management LP | Reduce 89.03% | -$1.49M | $184K | 0.11% | Aug 14, 2026 |
| Simplify Asset Management Inc. | Sell 100% | -$1.1M | $0 | 0.00% | Jul 16, 2026 |
| Kopp Family Office, LLC | Sell 100% | -$1.08M | $0 | 0.00% | Jul 9, 2026 |
| Nomura Asset Management International Inc. | Reduce 65.60% | -$1.03M | $540K | 0.00% | Aug 14, 2026 |
| Susquehanna Portfolio Strategies, LLC | Sell 100% | -$1.03M | $0 | 0.00% | Aug 14, 2026 |
| Seven Grand Managers, LLC | New Buy | +$919K | $919K | 0.04% | Aug 14, 2026 |
| Wellington Management Group LLP | Added 1.62% | +$915K | $57.5M | 0.01% | Aug 14, 2026 |
| CenterBook Partners LP | Sell 100% | -$887K | $0 | 0.00% | Aug 11, 2026 |
| Handelsbanken Fonder AB | New Buy | +$834K | $834K | 0.00% | Jul 10, 2026 |
| Twinbeech Capital LP | Reduce 54.22% | -$766K | $647K | 0.12% | Aug 14, 2026 |
| J. Safra Sarasin Holding AG | Added 47.61% | +$639K | $1.98M | 0.03% | Jul 31, 2026 |
| Hennion & Walsh Asset Management, Inc. | Added 19.55% | +$628K | $3.84M | 0.11% | Jul 8, 2026 |
| Rafferty Asset Management, LLC | Reduce 23.40% | -$610K | $2M | 0.00% | Aug 14, 2026 |
| Campbell & CO Investment Adviser LLC | Sell 100% | -$590K | $0 | 0.00% | Aug 3, 2026 |
| Doliver Advisors, LP | New Buy | +$551K | $551K | 0.12% | Jul 10, 2026 |
| Jennison Associates LLC | Sell 100% | -$549K | $0 | 0.00% | Aug 3, 2026 |
| HighVista Strategies LLC | Added 19.11% | +$471K | $2.94M | 0.67% | Aug 14, 2026 |
| Persistent Asset Partners Ltd | New Buy | +$468K | $468K | 0.14% | Aug 7, 2026 |
| Fideuram - Intesa Sanpaolo Private Banking S.P.A. | Added 32.53% | +$415K | $1.69M | 0.05% | Jul 23, 2026 |
| Quantinno Capital Management LP | New Buy | +$403K | $403K | 0.00% | Aug 13, 2026 |
| EntryPoint Capital, LLC | Sell 100% | -$400K | $0 | 0.00% | Aug 13, 2026 |
| Birchview Capital, LP | Sell 100% | -$393K | $0 | 0.00% | Aug 14, 2026 |
| DNB Asset Management AS | Added 123.82% | +$364K | $657K | 0.00% | Aug 11, 2026 |
| Bayforest Capital Ltd | New Buy | +$363K | $363K | 0.34% | Aug 5, 2026 |
| Montanova Capital, LLC | Sell 100% | -$327K | $0 | 0.00% | Aug 14, 2026 |
| Fisher Asset Management, LLC | Reduce 0.99% | -$320K | $32.2M | 0.01% | Aug 4, 2026 |
| J. Goldman & Co LP | Sell 100% | -$305K | $0 | 0.00% | Aug 14, 2026 |
| Allstate Corp | New Buy | +$275K | $275K | 0.00% | Aug 13, 2026 |
| Fox Run Management, L.L.C. | Sell 100% | -$241K | $0 | 0.00% | Aug 4, 2026 |
| Knights of Columbus Asset Advisors LLC | Added 22.09% | +$234K | $1.3M | 0.06% | Jul 31, 2026 |
| Cinctive Capital Management LP | Sell 100% | -$225K | $0 | 0.00% | Aug 14, 2026 |
| Virtus Investment Advisers, LLC | Added 137.14% | +$213K | $368K | 0.09% | Aug 11, 2026 |
| VANGUARD ASSET MANAGEMENT, Ltd | Added 26.04% | +$208K | $1.01M | 0.00% | Aug 13, 2026 |
| Nations Financial Group Inc, /Ia/ | New Buy | +$207K | $207K | 0.01% | Jul 23, 2026 |
| Profund Advisors LLC | Reduce 13.53% | -$157K | $1.01M | 0.03% | Aug 11, 2026 |
| DCF Advisers, LLC | Added 18.20% | +$107K | $698K | 0.12% | Aug 10, 2026 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | Reduce 4.14% | -$107K | $2.47M | 0.00% | Aug 13, 2026 |
| Bellevue Group AG | Added 0.09% | +$106K | $124M | 2.60% | Aug 14, 2026 |
| Greenland Capital Management LP | Reduce 9.09% | -$91.9K | $919K | 0.11% | Aug 12, 2026 |
| Ensign Peak Advisors, Inc | Added 56.59% | +$67.1K | $186K | 0.00% | Aug 14, 2026 |
| KLP Kapitalforvaltning As | Added 25.90% | +$66.1K | $321K | 0.00% | Aug 12, 2026 |
| Graham Capital Management, L.P. | Reduce 17.10% | -$58.1K | $282K | 0.01% | Aug 14, 2026 |
| State of New Jersey Common Pension Fund D | Added 12.25% | +$50.1K | $459K | 0.00% | Aug 4, 2026 |
| E Fund Management Co., Ltd. | Reduce 14.08% | -$46.2K | $282K | 0.01% | Aug 11, 2026 |
| KBC Group NV | Added 137.19% | +$44K | $76K | 0.00% | Aug 5, 2026 |
| Bessemer Group Inc | Reduce 82.97% | -$34.1K | $7K | 0.00% | Aug 12, 2026 |
| Pacer Advisors, Inc. | New Buy | +$33K | $33K | 0.00% | Aug 13, 2026 |
| IFG Advisory, LLC | New Buy | +$5K | $5K | 0.00% | Aug 14, 2026 |
| Quarry LP | New Buy | +$4.23K | $4.23K | 0.00% | Aug 14, 2026 |
| SMA Capital LLC | Sell 100% | -$3.97K | $0 | 0.00% | Aug 14, 2026 |
| Kemnay Advisory Services Inc. | Added 20.58% | +$2.99K | $17.5K | 0.00% | Aug 14, 2026 |
| J.Safra Asset Management Corp | Added 16.67% | +$2.5K | $17.5K | 0.00% | Aug 6, 2026 |
| Silver Grove Financial Group, Inc. | New Buy | +$2.13K | $2.13K | 0.00% | Aug 13, 2026 |
| LRI Investments, LLC | New Buy | +$845 | $845 | 0.00% | Jul 14, 2026 |
| Twin Peaks Wealth Advisors, LLC | Sell 100% | -$587 | $0 | 0.00% | Aug 13, 2026 |
| Zions Bancorporation, National Association | Reduce 17.78% | -$294 | $1.36K | 0.00% | Jul 31, 2026 |
| Versant Capital Management, Inc | Added 10.45% | +$257 | $2.72K | 0.00% | Jul 2, 2026 |
| Rossby Financial, LCC | Sell 100% | -$211 | $0 | 0.00% | Aug 4, 2026 |
| Stone House Investment Management, LLC | Sell 100% | -$176 | $0 | 0.00% | Aug 5, 2026 |
| MassMutual Private Wealth & Trust, FSB | Sell 100% | -$156 | $0 | 0.00% | Jul 2, 2026 |
| Pinnacle Wealth Planning Services, Inc. | New Buy | +$147 | $147 | 0.00% | Aug 7, 2026 |
| Keating Financial Advisory Services, Inc. | Sell 100% | -$20 | $0 | 0.00% | Aug 11, 2026 |
