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IONIS PHARMACEUTICALS INC hedge fund holdings

IONSNASDAQ
$43.54-0.46 (-1.05%)as of Oct 2, 2026

Every quarter, large institutional investment managers with over $100M in U.S.-listed assets under management disclose their U.S. equity holdings through 13F filings. Read together, those filings show which businesses professional capital is moving into and out of.

Price vs funds buying and selling

IONS · close · 13FReported Aug 14, 2026

Price vs funds buying and selling data

Showing the 1Y range: Oct 2, 2025 to Oct 2, 2026. Price (-36.3%). 0 fund reports plotted in this window as 0 markers; nearby trades of the same kind are grouped.

Transactions plotted on the price chart
DateCategoryPersonRoleActionAmountChange in holding
Funds buying · new + increased
Funds selling · reduced + closed
Net buyers vs sellers
Buying = new + increased; selling = reduced + closed. Counts exclude position changes under 5% of the fund's holding last quarter.

Price and fund activity data

Quarterly 13F fund buying and selling activity
QuarterFunds buyingFunds sellingBoughtSoldFilersReported
Q2 2025143119$605M$519M336Aug 14, 2025
Q3 2025179111$1.31B$1.34B413Nov 14, 2025
Q4 2025189141$1.74B$1.3B461Feb 14, 2026
Q1 2026172156$1.52B$1.77B464May 15, 2026
Q2 2026182145$1.4B$878M474Aug 14, 2026

Quarterly action breakdown

Q2 2026
474 filers
New position
52
$141M+1.78M sh
Increased
130
$1.26B+15.9M sh
Reduced
107
-$801M-10.1M sh
Out / sold
38
-$77.8M-981K sh
Last 4 quarters · free
Reported Aug 14, 2026
FundActionChange in dollarValue% of portfolioReported
T. Rowe Price Investment Management, Inc.Reduce 35.71%-$174M$314M0.21%Aug 14, 2026
Wellington Management Group LLPAdded 19.71%+$99.9M$607M0.10%Aug 14, 2026
Bellevue Group AGReduce 46.54%-$67.1M$77.1M1.62%Aug 14, 2026
Capital International InvestorsNew Buy+$65.3M$65.3M0.01%Aug 12, 2026
Polar Capital Holdings PlcAdded 75.29%+$49.5M$115M0.27%Aug 14, 2026
Summit Partners Public Asset Management, LLCReduce 43.93%-$48.9M$62.4M1.10%Aug 14, 2026
Artisan Partners Limited PartnershipAdded 28.26%+$46.1M$209M0.33%Aug 13, 2026
Nomura Asset Management International Inc.Added 65.60%+$40.8M$103M0.15%Aug 14, 2026
Capital World InvestorsAdded 2.28%+$38.3M$1.72B0.20%Aug 12, 2026
Davern Capital Partners, LPAdded 106.44%+$32.7M$63.3M10.80%Aug 13, 2026
Freestone Grove Partners LPNew Buy+$27M$27M0.17%Aug 14, 2026
Nomura Holdings IncAdded 252.55%+$22.8M$31.9M0.04%Aug 14, 2026
Carmignac GestionAdded 505.66%+$21.2M$25.5M0.33%Aug 13, 2026
Deep Track Capital, LPAdded 12.82%+$19.8M$174M2.54%Aug 14, 2026
Zurich Insurance Group LtdSell 100%-$18M$00.00%Aug 14, 2026
J. Goldman & Co LPReduce 82.84%-$15.5M$3.2M0.08%Aug 14, 2026
Eagle Health Investments LPNew Buy+$15.4M$15.4M2.56%Aug 10, 2026
Capital Fund Management S.A.Added 131.75%+$14.9M$26.1M0.12%Aug 13, 2026
BNP PARIBAS ASSET MANAGEMENT Holding S.A.Reduce 19.10%-$13.7M$58.2M0.06%Aug 13, 2026
Handelsbanken Fonder ABAdded 79.15%+$13.4M$30.4M0.09%Jul 10, 2026
Aberdeen Group plcAdded 143.67%+$13M$22M0.03%Jul 31, 2026
Pictet Asset Management Holding SAAdded 11.29%+$12.9M$127M0.12%Jul 30, 2026
Ikarian Capital, LLCSell 100%-$9.54M$00.00%Aug 14, 2026
Empowered Funds, LLCAdded 116.35%+$9.51M$17.7M0.09%Aug 17, 2026
Integral Health Asset Management, LLCSell 100%-$9.39M$00.00%Aug 14, 2026
Polymer Capital Management (HK) LTDAdded 190.68%+$9.25M$14.1M0.71%Aug 13, 2026
Groupama Asset ManagmentAdded 13.65%+$9.03M$75.2M0.95%Aug 14, 2026
Atle Fund Management ABAdded 391.99%+$8.66M$10.9M2.93%Jul 24, 2026
Adage Capital Partners GP, L.L.C.Added 200.00%+$7.93M$11.9M0.02%Aug 14, 2026
Susquehanna Portfolio Strategies, LLCReduce 95.90%-$7.3M$312K0.01%Aug 14, 2026
Public Employees Retirement Association of ColoradoAdded 481.11%+$5.95M$7.18M0.02%Aug 11, 2026
CSS LLCAdded 92.54%+$5.8M$12.1M0.47%Aug 14, 2026
Lisanti Capital Growth, LLCSell 100%-$5.68M$00.00%Aug 10, 2026
Swedbank ABAdded 196.61%+$5.03M$7.59M0.01%Jul 15, 2026
Perceptive Advisors LLCAdded 12.30%+$4.92M$44.9M0.67%Aug 14, 2026
CenterBook Partners LPReduce 40.84%-$4.89M$7.08M0.35%Aug 11, 2026
Schroder Investment Management GroupNew Buy+$4.75M$4.75M0.00%Aug 13, 2026
Sovran Advisors, LLCNew Buy+$4.7M$4.7M0.35%Jul 30, 2026
Tetragon Partners GP LtdAdded 132.67%+$4.39M$7.7M1.21%Aug 13, 2026
Thrivent Financial for LutheransAdded 529.82%+$4.19M$4.98M0.01%Aug 14, 2026
Great Lakes Advisors, LLCReduce 43.73%-$4.12M$5.31M0.04%Aug 10, 2026
Fred Alger Management, LLCAdded 177.42%+$4M$6.26M0.02%Aug 14, 2026
Campbell & CO Investment Adviser LLCAdded 1500.52%+$3.69M$3.94M0.21%Aug 3, 2026
DAVENPORT & Co LLCAdded 19.19%+$3.63M$22.5M0.11%Jul 13, 2026
West Michigan Advisors, LLCSell 100%-$3.35M$00.00%Aug 21, 2026
First Trust Advisors LPReduce 8.79%-$3.26M$33.9M0.02%Aug 11, 2026
E Fund Management Co., Ltd.Reduce 88.07%-$3.26M$442K0.01%Aug 11, 2026
Ensign Peak Advisors, IncReduce 80.18%-$2.92M$723K0.00%Aug 14, 2026
Amova Asset Management Americas, Inc.Reduce 41.67%-$2.7M$3.78M0.05%Aug 13, 2026
Sumitomo Mitsui Trust Group, Inc.Reduce 41.58%-$2.7M$3.79M0.00%Jul 30, 2026
Rhenman & Partners Asset Management ABReduce 35.52%-$2.62M$4.75M0.45%Aug 13, 2026
Eversept Partners, LPAdded 5.15%+$2.58M$52.7M2.73%Aug 14, 2026
Tocqueville Asset Management L.P.Added 14.59%+$2.54M$19.9M0.26%Aug 10, 2026
Ethic Inc.New Buy+$2.51M$2.51M0.03%Jul 29, 2026
Bamco IncReduce 68.89%-$2.46M$1.11M0.00%Aug 14, 2026
Privium Fund Management B.V.Added 10.31%+$2.37M$25.4M4.66%Aug 7, 2026
Van Eck Associates CorpAdded 83.73%+$2.29M$5.03M0.00%Aug 14, 2026
EFG International AGAdded 30.67%+$2.29M$9.74M0.18%Aug 14, 2026
Arrowpoint Investment Partners (Singapore) Pte. Ltd.Reduce 68.35%-$2.11M$978K0.21%Aug 13, 2026
BI Asset Management Fondsmaeglerselskab A/SNew Buy+$2.04M$2.04M0.02%Aug 10, 2026
Florida Financial Advisors, LLCSell 100%-$1.94M$00.00%Aug 10, 2026
Edmond de Rothschild Holding S.A.Reduce 17.40%-$1.89M$8.99M0.12%Aug 10, 2026
Rafferty Asset Management, LLCReduce 37.57%-$1.8M$2.99M0.01%Aug 14, 2026
Gotham Asset Management, LLCAdded 22.52%+$1.77M$9.61M0.02%Aug 14, 2026
Exome Asset Management LLCReduce 19.89%-$1.74M$6.99M4.31%Aug 14, 2026
Qsemble Capital Management, LPReduce 84.91%-$1.73M$308K0.04%Aug 3, 2026
Stanley-Laman Group, Ltd.Added 54.79%+$1.71M$4.82M0.49%Aug 5, 2026
Worldquant Millennium Advisors LLCAdded 75.39%+$1.67M$3.88M0.01%Aug 14, 2026
Natixis Advisors, LLCAdded 88.56%+$1.67M$3.55M0.00%Aug 14, 2026
KBC Group NVAdded 69.22%+$1.66M$4.05M0.01%Aug 5, 2026
Jefferies Financial Group Inc.Reduce 34.54%-$1.62M$3.07M0.02%Aug 17, 2026
Voleon Capital Management LPReduce 87.58%-$1.6M$227K0.00%Aug 14, 2026
Sector Gamma AsAdded 11.80%+$1.59M$15M3.26%Aug 12, 2026
Boone Capital Management LLCAdded 3.89%+$1.54M$41.2M9.64%Aug 14, 2026
Readystate Asset Management LPSell 100%-$1.53M$00.00%Aug 14, 2026
Canada Pension Plan Investment BoardAdded 136.17%+$1.52M$2.64M0.00%Aug 14, 2026
DCF Advisers, LLCReduce 33.04%-$1.47M$2.97M0.53%Aug 10, 2026
VANGUARD ASSET MANAGEMENT, LtdAdded 12.79%+$1.39M$12.3M0.01%Aug 13, 2026
Voloridge Investment Management, LLCReduce 2.59%-$1.38M$52M0.22%Aug 14, 2026
Graham Capital Management, L.P.New Buy+$1.33M$1.33M0.02%Aug 14, 2026
Pinnacle Associates LtdReduce 3.83%-$1.32M$33.3M0.36%Aug 3, 2026
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am MainReduce 9.76%-$1.3M$12M0.01%Aug 14, 2026
BIT Capital GmbHNew Buy+$1.29M$1.29M0.04%Aug 12, 2026
Tidal Investments LLCAdded 42.83%+$1.17M$3.9M0.01%Aug 13, 2026
Massachusetts Financial Services CoReduce 2.15%-$1.13M$51.7M0.02%Aug 3, 2026
Braidwell LPReduce 10.77%-$1.12M$9.26M0.34%Aug 14, 2026
Highland Capital Management, LLCSell 100%-$963K$00.00%Jul 21, 2026
ARK Investment Management LLCAdded 4.18%+$956K$23.8M0.15%Aug 14, 2026
Edgestream Partners, L.P.Reduce 17.05%-$924K$4.5M0.13%Aug 11, 2026
Militia Capital Management LLCNew Buy+$904K$904K0.03%Aug 12, 2026
M&G PLCReduce 78.58%-$895K$244K0.00%Aug 6, 2026
Evolve Private Wealth, LLCNew Buy+$845K$845K0.05%Aug 12, 2026
Capstone Capital Management LtdSell 100%-$832K$00.00%Jul 20, 2026
Calamos Advisors LLCAdded 48.42%+$759K$2.33M0.01%Jul 31, 2026
Quantinno Capital Management LPAdded 16.96%+$746K$5.15M0.01%Aug 13, 2026
NewEdge Wealth, LLCNew Buy+$712K$712K0.01%Aug 10, 2026
DeepCurrents Investment Group LLCAdded 32.05%+$697K$2.87M0.09%Aug 14, 2026
iA Global Asset Management Inc.New Buy+$686K$686K0.01%Jul 29, 2026
Aigen Investment Management, LPSell 100%-$660K$00.00%Aug 14, 2026
Inspire Investing, LLCNew Buy+$644K$644K0.03%Aug 12, 2026

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