| First Light Asset Management, LLC | New Buy | +$39.1M | $39.1M | 2.38% | Aug 14, 2026 |
| Viking Global Investors LP | Reduce 51.71% | -$30.8M | $28.8M | 0.08% | Aug 14, 2026 |
| Octagon Capital Advisors LP | Reduce 78.79% | -$21.8M | $5.87M | 0.53% | Aug 14, 2026 |
| Frontier Capital Management Co LLC | Added 53.98% | +$20.1M | $57.3M | 0.53% | Aug 14, 2026 |
| Saturn V Capital Management LP | New Buy | +$19.6M | $19.6M | 2.81% | Aug 14, 2026 |
| Jones Hill Capital LP | Added 261.78% | +$18.1M | $25M | 5.31% | Aug 13, 2026 |
| Vestal Point Capital, LP | Added 43.09% | +$17.4M | $57.8M | 1.35% | Aug 14, 2026 |
| Logos Global Management LP | Reduce 21.67% | -$9.7M | $35.1M | 1.51% | Aug 14, 2026 |
| Wellington Management Group LLP | Added 9.55% | +$9.24M | $106M | 0.02% | Aug 14, 2026 |
| Pictet Asset Management Holding SA | Added 18.04% | +$5.74M | $37.6M | 0.04% | Jul 30, 2026 |
| Superstring Capital Management LP | Added 108.38% | +$5.09M | $9.78M | 6.17% | Aug 14, 2026 |
| Rock Springs Capital Management LP | New Buy | +$4.85M | $4.85M | 0.24% | Aug 14, 2026 |
| MPM Bioimpact LLC | Reduce 6.82% | -$4.19M | $57.3M | 3.50% | Aug 14, 2026 |
| GMT Capital Corp | Sell 100% | -$3.79M | $0 | 0.00% | Aug 14, 2026 |
| Affinity Asset Advisors, LLC | Reduce 10.00% | -$3.73M | $33.6M | 1.52% | Aug 13, 2026 |
| Integral Health Asset Management, LLC | New Buy | +$3.73M | $3.73M | 0.15% | Aug 14, 2026 |
| Burkehill Global Management, LP | Added 38.10% | +$3.73M | $13.5M | 0.49% | Aug 14, 2026 |
| Artia Global Partners LP | Added 9.80% | +$3.68M | $41.2M | 7.61% | Aug 14, 2026 |
| Swiss Life Asset Management Ltd | Sell 100% | -$3.66M | $0 | 0.00% | Jul 29, 2026 |
| Pivotal bioVenture Partners Investment Advisor LLC | Added 12.16% | +$3.52M | $32.5M | 10.56% | Aug 13, 2026 |
| Silverarc Capital Management, LLC | Added 32.67% | +$3.11M | $12.6M | 1.31% | Aug 13, 2026 |
| J. Goldman & Co LP | Reduce 65.82% | -$2.91M | $1.51M | 0.04% | Aug 14, 2026 |
| Seven Grand Managers, LLC | New Buy | +$2.8M | $2.8M | 0.11% | Aug 14, 2026 |
| Propel Bio Management, LLC | Sell 100% | -$2.65M | $0 | 0.00% | Aug 13, 2026 |
| Harvest Investment Services, LLC | New Buy | +$2.15M | $2.15M | 0.33% | Aug 14, 2026 |
| Peregrine Capital Management LLC | Reduce 16.24% | -$1.61M | $8.29M | 0.27% | Jul 17, 2026 |
| Sphera Funds Management Ltd. | Reduce 13.07% | -$1.4M | $9.31M | 1.21% | Aug 14, 2026 |
| Nan Fung Trinity (Hk) Ltd | Added 6.18% | +$1.32M | $22.6M | 2.23% | Jul 24, 2026 |
| Ensign Peak Advisors, Inc | Reduce 14.75% | -$1.28M | $7.39M | 0.01% | Aug 14, 2026 |
| Fred Alger Management, LLC | New Buy | +$1.24M | $1.24M | 0.00% | Aug 14, 2026 |
| Emerald Mutual Fund Advisers Trust | Reduce 4.08% | -$961K | $22.6M | 0.79% | Aug 5, 2026 |
| Teachers Retirement System of the State of Kentucky | New Buy | +$933K | $933K | 0.01% | Aug 12, 2026 |
| Emerald Advisers, LLC | Reduce 2.28% | -$782K | $33.5M | 0.79% | Aug 5, 2026 |
| Simplify Asset Management Inc. | Sell 100% | -$780K | $0 | 0.00% | Jul 16, 2026 |
| Campbell & CO Investment Adviser LLC | Added 104.45% | +$780K | $1.53M | 0.08% | Aug 3, 2026 |
| Eventide Asset Management, LLC | Added 1.44% | +$703K | $49.6M | 0.66% | Aug 14, 2026 |
| Dymon Asia Capital (Singapore) Pte. Ltd. | New Buy | +$658K | $658K | 0.03% | Jul 23, 2026 |
| Opaleye Management Inc. | Reduce 10.17% | -$655K | $5.78M | 0.52% | Aug 14, 2026 |
| Flputnam Investment Management Co | Reduce 2.37% | -$471K | $19.4M | 0.23% | Aug 6, 2026 |
| Checkpoint Capital L.P. | Added 50.00% | +$466K | $1.4M | 0.36% | Aug 14, 2026 |
| VANGUARD ASSET MANAGEMENT, Ltd | Added 35.76% | +$355K | $1.35M | 0.00% | Aug 13, 2026 |
| Seven Fleet Capital Management LP | Added 67.95% | +$337K | $833K | 0.14% | Aug 17, 2026 |
| Graham Capital Management, L.P. | New Buy | +$335K | $335K | 0.01% | Aug 14, 2026 |
| Cowa, LLC | New Buy | +$335K | $335K | 0.08% | Aug 6, 2026 |
| IMC-Chicago, LLC | Sell 100% | -$290K | $0 | 0.00% | Aug 6, 2026 |
| Bridgefront Capital, LLC | New Buy | +$283K | $283K | 0.07% | Aug 14, 2026 |
| Lanark Financial, Inc. | Reduce 88.24% | -$280K | $37.3K | 0.00% | Jul 21, 2026 |
| Diadema Partners LP | Sell 100% | -$258K | $0 | 0.00% | Aug 14, 2026 |
| Xponance LLC | New Buy | +$191K | $191K | 0.00% | Aug 10, 2026 |
| Albion Financial Group | New Buy | +$187K | $187K | 0.01% | Jul 22, 2026 |
| China Universal Asset Management Co., Ltd. | Reduce 29.18% | -$178K | $433K | 0.03% | Jul 24, 2026 |
| Trust Co of Toledo NA | Reduce 5.70% | -$140K | $2.31M | 0.19% | Jul 16, 2026 |
| Avidity Partners Management LP | Reduce 50.00% | -$124K | $124K | 0.02% | Aug 14, 2026 |
| SIH Partners, LLLP | Sell 100% | -$119K | $0 | 0.00% | Aug 14, 2026 |
| Vanguard Investments Australia, Ltd. | Added 20.22% | +$78.8K | $468K | 0.00% | Aug 13, 2026 |
| KLP Kapitalforvaltning As | Added 18.58% | +$63.4K | $405K | 0.00% | Aug 12, 2026 |
| F/m Investments LLC | Added 1.13% | +$48.6K | $4.37M | 0.22% | Aug 5, 2026 |
| Rafferty Asset Management, LLC | Added 20.64% | +$47.3K | $276K | 0.00% | Aug 14, 2026 |
| Persistent Asset Partners Ltd | Reduce 8.28% | -$43.1K | $477K | 0.14% | Aug 7, 2026 |
| State of New Jersey Common Pension Fund D | Added 6.33% | +$34.4K | $578K | 0.00% | Aug 4, 2026 |
| Kennedy Capital Management LLC | Added 2.95% | +$33.8K | $1.18M | 0.02% | Aug 14, 2026 |
| Kemnay Advisory Services Inc. | New Buy | +$21.8K | $21.8K | 0.00% | Aug 14, 2026 |
| HighVista Strategies LLC | Reduce 0.92% | -$9.18K | $989K | 0.23% | Aug 14, 2026 |
| Harbour Capital Advisors, LLC | Reduce 1.23% | -$8.92K | $717K | 0.13% | Jul 15, 2026 |
| Aster Capital Management (DIFC) Ltd | New Buy | +$7.78K | $7.78K | 0.00% | Aug 14, 2026 |
| Vontobel Holding Ltd. | Reduce 3.48% | -$6.75K | $187K | 0.00% | Aug 3, 2026 |
| Z3 Capital Partners, LLC | Reduce 0.76% | -$5.6K | $732K | 0.15% | Jul 28, 2026 |
| Oppenheimer & Co Inc | Reduce 0.26% | -$4.77K | $1.86M | 0.02% | Aug 3, 2026 |
| Versant Capital Management, Inc | Sell 100% | -$2.77K | $0 | 0.00% | Jul 2, 2026 |
| Kingsview Wealth Management, LLC | Added 0.79% | +$2.33K | $296K | 0.00% | Aug 19, 2026 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | Reduce 6.89% | -$2.29K | $31K | 0.00% | Aug 13, 2026 |
| Optimize Financial Inc. | Reduce 0.34% | -$2.05K | $593K | 0.21% | Aug 27, 2026 |
| Frazier Life Sciences Management, L.P. | Reduce 0.00% | -$1.87K | $185M | 4.04% | Aug 14, 2026 |
| Silver Grove Financial Group, Inc. | New Buy | +$746 | $746 | 0.00% | Aug 13, 2026 |
| Diversified Trust Co | Added 0.08% | +$354 | $438K | 0.01% | Jul 17, 2026 |
| Twin Peaks Wealth Advisors, LLC | Sell 100% | -$346 | $0 | 0.00% | Aug 13, 2026 |
| Stone House Investment Management, LLC | Added 1600.00% | +$298 | $317 | 0.00% | Aug 5, 2026 |
| Profund Advisors LLC | Reduce 0.04% | -$149 | $394K | 0.01% | Aug 11, 2026 |
| Hughes Financial Services, LLC | Added 33.33% | +$19 | $75 | 0.00% | Jul 20, 2026 |
| Keating Financial Advisory Services, Inc. | Added 100.00% | +$19 | $37 | 0.00% | Aug 11, 2026 |
