Definium Therapeutics, Inc. hedge fund holdings
DFTXNASDAQ$37.40-0.20 (-0.53%)as of Oct 2, 2026
Every quarter, large institutional investment managers with over $100M in U.S.-listed assets under management disclose their U.S. equity holdings through 13F filings. Read together, those filings show which businesses professional capital is moving into and out of.
Price vs funds buying and selling
DFTX · close · 13FReported Aug 14, 2026Price vs funds buying and selling data
Showing the 1Y range: Oct 2, 2025 to Oct 2, 2026. Price (+206.1%). 0 fund reports plotted in this window as 0 markers; nearby trades of the same kind are grouped.
| Date | Category | Person | Role | Action | Amount | Change in holding |
|---|
Funds buying · new + increased
Funds selling · reduced + closed
Net buyers vs sellers
Buying = new + increased; selling = reduced + closed. Counts exclude position changes under 5% of the fund's holding last quarter.Price and fund activity data
| Quarter | Funds buying | Funds selling | Bought | Sold | Filers | Reported |
|---|---|---|---|---|---|---|
| Q4 2025 | 6 | 0 | $150M | $0 | 8 | Feb 14, 2026 |
| Q1 2026 | 191 | 5 | $916M | $51.9M | 232 | May 15, 2026 |
| Q2 2026 | 213 | 74 | $1.79B | $366M | 330 | Aug 14, 2026 |
Quarterly action breakdown
Q2 2026
330 filersNew position
119$758M+16.1M sh
Increased
94$1.04B+22M sh
Reduced
48-$223M-4.73M sh
Out / sold
26-$143M-3.04M sh
Last 4 quarters · free
Reported Aug 14, 2026
| Fund | Action | Change in dollar | Value | % of portfolio | Reported |
|---|---|---|---|---|---|
| Capital World Investors | New Buy | +$252M | $252M | 0.03% | Aug 12, 2026 |
| Capital International Investors | New Buy | +$139M | $139M | 0.03% | Aug 12, 2026 |
| Avoro Capital Advisors LLC | Added 43.78% | +$103M | $338M | 3.04% | Aug 14, 2026 |
| Wellington Management Group LLP | Added 126.08% | +$77.4M | $139M | 0.02% | Aug 14, 2026 |
| Ra Capital Management, L.P. | New Buy | +$70.6M | $70.6M | 0.61% | Aug 14, 2026 |
| ArrowMark Colorado Holdings LLC | Reduce 64.63% | -$48.5M | $26.5M | 1.10% | Aug 13, 2026 |
| Driehaus Capital Management LLC | Added 15.79% | +$43.9M | $322M | 1.87% | Aug 14, 2026 |
| Polar Capital Holdings Plc | New Buy | +$36.6M | $36.6M | 0.09% | Aug 14, 2026 |
| Trails Edge Capital Partners, LP | Sell 100% | -$32.9M | $0 | 0.00% | Aug 14, 2026 |
| Bamco Inc | New Buy | +$24.5M | $24.5M | 0.04% | Aug 14, 2026 |
| Octagon Capital Advisors LP | Added 20.90% | +$24M | $139M | 12.47% | Aug 14, 2026 |
| Siren, L.L.C. | Added 54.38% | +$23.5M | $66.8M | 1.35% | Aug 13, 2026 |
| Catalio Capital Management, LP | Reduce 45.79% | -$22.4M | $26.5M | 4.97% | Aug 14, 2026 |
| Great Point Partners LLC | New Buy | +$20M | $20M | 3.78% | Aug 14, 2026 |
| Cormorant Asset Management, LP | New Buy | +$18.8M | $18.8M | 0.96% | Aug 14, 2026 |
| Silverarc Capital Management, LLC | New Buy | +$18.8M | $18.8M | 1.96% | Aug 13, 2026 |
| Boxer Capital Management, LLC | Added 66.83% | +$18.8M | $47M | 3.54% | Aug 14, 2026 |
| Assetmark, Inc | New Buy | +$18.7M | $18.7M | 0.03% | Jul 30, 2026 |
| Duquesne Family Office LLC | New Buy | +$16.8M | $16.8M | 0.32% | Aug 14, 2026 |
| Holocene Advisors, LP | Reduce 27.05% | -$13.9M | $37.5M | 0.08% | Aug 14, 2026 |
| Deep Track Capital, LP | Reduce 8.33% | -$11.8M | $129M | 1.88% | Aug 14, 2026 |
| SEB Asset Management AB | New Buy | +$9.8M | $9.8M | 0.04% | Aug 4, 2026 |
| Tri Locum Partners LP | Reduce 55.90% | -$9.72M | $7.67M | 0.94% | Aug 14, 2026 |
| Emerald Advisers, LLC | New Buy | +$8.41M | $8.41M | 0.20% | Aug 5, 2026 |
| Aberdeen Group plc | New Buy | +$8.23M | $8.23M | 0.01% | Jul 31, 2026 |
| Superstring Capital Management LP | Reduce 46.43% | -$7.68M | $8.86M | 5.59% | Aug 14, 2026 |
| Adage Capital Partners GP, L.L.C. | Reduce 13.04% | -$7.06M | $47M | 0.07% | Aug 14, 2026 |
| Integral Health Asset Management, LLC | Added 37.50% | +$7.06M | $25.9M | 1.02% | Aug 14, 2026 |
| BIT Capital GmbH | Reduce 53.83% | -$7.03M | $6.03M | 0.18% | Aug 12, 2026 |
| Rock Springs Capital Management LP | New Buy | +$6.74M | $6.74M | 0.33% | Aug 14, 2026 |
| SummitTX Capital, L.P. | New Buy | +$6.7M | $6.7M | 0.17% | Aug 14, 2026 |
| Patient Square Capital LP | Sell 100% | -$6.26M | $0 | 0.00% | Aug 12, 2026 |
| Atika Capital Management LLC | New Buy | +$5.74M | $5.74M | 0.38% | Aug 13, 2026 |
| Emerald Mutual Fund Advisers Trust | New Buy | +$5.7M | $5.7M | 0.20% | Aug 5, 2026 |
| RTW Investments, LP | Added 33.33% | +$4.7M | $18.8M | 0.16% | Aug 14, 2026 |
| Keystone Investors Pte Ltd | New Buy | +$4.47M | $4.47M | 0.24% | Aug 14, 2026 |
| Pier Capital, LLC | New Buy | +$4.17M | $4.17M | 0.55% | Aug 5, 2026 |
| Sofinnova Investments, Inc. | Reduce 25.65% | -$4.15M | $12M | 0.62% | Aug 14, 2026 |
| Tetragon Partners GP Ltd | Added 43.50% | +$4.09M | $13.5M | 2.13% | Aug 13, 2026 |
| Squadron Capital Management LLC | New Buy | +$4M | $4M | 1.24% | Aug 14, 2026 |
| Ensign Peak Advisors, Inc | Reduce 14.75% | -$3.8M | $21.9M | 0.04% | Aug 14, 2026 |
| Logos Global Management LP | New Buy | +$3.76M | $3.76M | 0.16% | Aug 14, 2026 |
| HighVista Strategies LLC | Added 30.68% | +$2.68M | $11.4M | 2.60% | Aug 14, 2026 |
| Eversept Partners, LP | Added 35.13% | +$2.66M | $10.2M | 0.53% | Aug 14, 2026 |
| Soviero Asset Management, LP | Sell 100% | -$2.65M | $0 | 0.00% | Aug 14, 2026 |
| Moody Aldrich Partners LLC | New Buy | +$2.4M | $2.4M | 0.43% | Jul 15, 2026 |
| Rosalind Advisors, Inc. | Sell 100% | -$2.36M | $0 | 0.00% | Aug 14, 2026 |
| Seven Fleet Capital Management LP | Added 48.82% | +$2.29M | $6.99M | 1.15% | Aug 17, 2026 |
| Polymer Capital Management (HK) LTD | New Buy | +$2.07M | $2.07M | 0.11% | Aug 13, 2026 |
| PFM Health Sciences, LP | Added 21.29% | +$2.06M | $11.7M | 1.01% | Aug 14, 2026 |
| Rathbones Group PLC | Reduce 62.25% | -$1.77M | $1.07M | 0.00% | Jul 23, 2026 |
| Fred Alger Management, LLC | Added 35.90% | +$1.56M | $5.89M | 0.02% | Aug 14, 2026 |
| Vestmark Advisory Solutions, Inc. | New Buy | +$1.45M | $1.45M | 0.01% | Aug 14, 2026 |
| Quantinno Capital Management LP | Added 76.89% | +$1.45M | $3.32M | 0.00% | Aug 13, 2026 |
| AdvisorShares Investments LLC | Added 32.95% | +$1.41M | $5.71M | 0.69% | Aug 11, 2026 |
| Stableford Capital II LLC | New Buy | +$1.28M | $1.28M | 0.44% | Jul 6, 2026 |
| KLP Kapitalforvaltning As | New Buy | +$1.18M | $1.18M | 0.00% | Aug 12, 2026 |
| PSP Research LLC | Reduce 71.26% | -$1.17M | $470K | 0.25% | Jul 9, 2026 |
| VANGUARD ASSET MANAGEMENT, Ltd | Added 45.51% | +$1.16M | $3.7M | 0.00% | Aug 13, 2026 |
| Teachers Retirement System of the State of Kentucky | New Buy | +$1.15M | $1.15M | 0.01% | Aug 12, 2026 |
| Eventide Asset Management, LLC | Added 3.47% | +$1.12M | $33.4M | 0.45% | Aug 14, 2026 |
| Ikarian Capital, LLC | Sell 100% | -$1.11M | $0 | 0.00% | Aug 14, 2026 |
| IFG Advisory, LLC | New Buy | +$1.04M | $1.04M | 0.04% | Aug 14, 2026 |
| Birchview Capital, LP | New Buy | +$941K | $941K | 0.44% | Aug 14, 2026 |
| Fore Capital, LLC | New Buy | +$941K | $941K | 0.28% | Aug 10, 2026 |
| Cinctive Capital Management LP | Added 127.47% | +$753K | $1.34M | 0.05% | Aug 14, 2026 |
| Cary Street Partners Financial LLC | New Buy | +$733K | $733K | 0.02% | Jul 17, 2026 |
| Diadema Partners LP | New Buy | +$727K | $727K | 0.09% | Aug 14, 2026 |
| Caxton Associates LLP | Sell 100% | -$704K | $0 | 0.00% | Aug 14, 2026 |
| FORA Capital, LLC | New Buy | +$629K | $629K | 0.04% | Aug 13, 2026 |
| Dymon Asia Capital (Singapore) Pte. Ltd. | New Buy | +$625K | $625K | 0.03% | Jul 23, 2026 |
| Xponance LLC | New Buy | +$598K | $598K | 0.00% | Aug 10, 2026 |
| Axq Capital, LP | New Buy | +$585K | $585K | 0.06% | Aug 6, 2026 |
| Swiss Life Asset Management Ltd | Reduce 68.23% | -$570K | $265K | 0.00% | Jul 29, 2026 |
| Elevation Point Wealth Partners, LLC | New Buy | +$535K | $535K | 0.01% | Aug 12, 2026 |
| Capital Fund Management S.A. | New Buy | +$476K | $476K | 0.00% | Aug 13, 2026 |
| Campbell & CO Investment Adviser LLC | Sell 100% | -$468K | $0 | 0.00% | Aug 3, 2026 |
| Diversify Advisory Services, LLC | New Buy | +$428K | $428K | 0.01% | Aug 10, 2026 |
| Fearless Solutions, LLC dba Best Invest | New Buy | +$414K | $414K | 0.22% | Jul 22, 2026 |
| Palumbo Wealth Management LLC | Reduce 22.86% | -$408K | $1.38M | 0.29% | Aug 12, 2026 |
| Virtus Investment Advisers, LLC | Reduce 39.15% | -$400K | $622K | 0.14% | Aug 11, 2026 |
| Fieldview Capital Management, LLC | New Buy | +$400K | $400K | 0.11% | Aug 14, 2026 |
| Bellevue Group AG | New Buy | +$395K | $395K | 0.01% | Aug 14, 2026 |
| Vanguard Investments Australia, Ltd. | Added 38.10% | +$367K | $1.33M | 0.00% | Aug 13, 2026 |
| OMERS ADMINISTRATION Corp | New Buy | +$358K | $358K | 0.00% | Aug 13, 2026 |
| Fiduciary Financial Advisors | New Buy | +$352K | $352K | 0.04% | Aug 14, 2026 |
| EntryPoint Capital, LLC | New Buy | +$345K | $345K | 0.08% | Aug 13, 2026 |
| Hollencrest Capital Management | Reduce 96.80% | -$336K | $11.1K | 0.00% | Aug 13, 2026 |
| Chiron Capital Management, LLC | New Buy | +$329K | $329K | 0.30% | Jul 21, 2026 |
| McAdam, LLC | New Buy | +$324K | $324K | 0.01% | Aug 4, 2026 |
| Sig Brokerage, LP | New Buy | +$309K | $309K | 0.01% | Aug 14, 2026 |
| AMG National Trust Bank | New Buy | +$300K | $300K | 0.01% | Aug 7, 2026 |
| Insigneo Advisory Services, LLC | New Buy | +$298K | $298K | 0.01% | Aug 14, 2026 |
| Waldron Private Wealth LLC | New Buy | +$297K | $297K | 0.01% | Jul 20, 2026 |
| Bailard, Inc. | New Buy | +$295K | $295K | 0.01% | Jul 30, 2026 |
| Fiduciary Alliance LLC | New Buy | +$282K | $282K | 0.02% | Jul 20, 2026 |
| Retirement Financial Solutions, LLC | New Buy | +$282K | $282K | 0.07% | Jul 30, 2026 |
| Beck Bode, LLC | New Buy | +$279K | $279K | 0.04% | Aug 13, 2026 |
| CRA Financial Services, LLC | New Buy | +$275K | $275K | 0.03% | Jul 24, 2026 |
| Scotia Capital Inc. | Reduce 14.37% | -$274K | $1.64M | 0.01% | Aug 11, 2026 |