| Polar Capital Holdings Plc | Added 26.94% | +$69.3M | $326M | 0.77% | Aug 14, 2026 |
| Venrock Adviser, LLC | Reduce 69.51% | -$60.9M | $26.7M | 0.81% | Aug 14, 2026 |
| First Light Asset Management, LLC | Added 574.08% | +$58.8M | $69.1M | 4.20% | Aug 14, 2026 |
| Adage Capital Partners GP, L.L.C. | New Buy | +$55M | $55M | 0.08% | Aug 14, 2026 |
| Siren, L.L.C. | Added 137.78% | +$52.2M | $90.1M | 1.82% | Aug 13, 2026 |
| Samlyn Capital, LLC | New Buy | +$46.3M | $46.3M | 0.75% | Aug 14, 2026 |
| Tri Locum Partners LP | New Buy | +$44M | $44M | 5.41% | Aug 14, 2026 |
| Bellevue Group AG | Reduce 35.80% | -$42.2M | $75.6M | 1.59% | Aug 14, 2026 |
| Vestal Point Capital, LP | Added 23.08% | +$38.1M | $203M | 4.74% | Aug 14, 2026 |
| Jones Hill Capital LP | Reduce 91.59% | -$27.6M | $2.53M | 0.54% | Aug 13, 2026 |
| Silverarc Capital Management, LLC | New Buy | +$24.8M | $24.8M | 2.58% | Aug 13, 2026 |
| Rock Springs Capital Management LP | Reduce 43.78% | -$18.4M | $23.6M | 1.15% | Aug 14, 2026 |
| Lord, Abbett & Co. LLC | New Buy | +$16.8M | $16.8M | 0.05% | Aug 14, 2026 |
| First Turn Management, LLC | Added 52.98% | +$16.8M | $48.4M | 5.18% | Aug 14, 2026 |
| T. Rowe Price Investment Management, Inc. | New Buy | +$15.3M | $15.3M | 0.01% | Aug 14, 2026 |
| Capricorn Fund Managers Ltd | Sell 100% | -$14.5M | $0 | 0.00% | Jul 24, 2026 |
| Novo Holdings A/S | Reduce 21.88% | -$14.2M | $50.8M | 2.95% | Aug 14, 2026 |
| Avidity Partners Management LP | Reduce 31.25% | -$12.7M | $27.9M | 4.47% | Aug 14, 2026 |
| Pictet Asset Management Holding SA | Added 24.98% | +$11.8M | $59M | 0.06% | Jul 30, 2026 |
| Deep Track Capital, LP | New Buy | +$11.4M | $11.4M | 0.17% | Aug 14, 2026 |
| Nicholas Investment Partners, LP | Added 114.27% | +$10.6M | $19.9M | 1.12% | Aug 14, 2026 |
| Seven Fleet Capital Management LP | Added 122.76% | +$10.2M | $18.5M | 3.06% | Aug 17, 2026 |
| Longaeva Partners L.P. | Added 176.44% | +$10.1M | $15.9M | 0.35% | Aug 14, 2026 |
| Squadron Capital Management LLC | New Buy | +$8.12M | $8.12M | 2.52% | Aug 14, 2026 |
| Cormorant Asset Management, LP | New Buy | +$7.61M | $7.61M | 0.39% | Aug 14, 2026 |
| Integral Health Asset Management, LLC | New Buy | +$7.61M | $7.61M | 0.30% | Aug 14, 2026 |
| Eversept Partners, LP | New Buy | +$6.93M | $6.93M | 0.36% | Aug 14, 2026 |
| Ikarian Capital, LLC | New Buy | +$6.42M | $6.42M | 0.69% | Aug 14, 2026 |
| Exome Asset Management LLC | Reduce 54.47% | -$6.08M | $5.09M | 3.14% | Aug 14, 2026 |
| Affinity Asset Advisors, LLC | Reduce 14.81% | -$4.41M | $25.4M | 1.15% | Aug 13, 2026 |
| J. Goldman & Co LP | Added 291.21% | +$4.24M | $5.69M | 0.15% | Aug 14, 2026 |
| DV Equities, LLC | New Buy | +$3.87M | $3.87M | 0.55% | Aug 14, 2026 |
| Logos Global Management LP | Reduce 13.89% | -$3.81M | $23.6M | 1.02% | Aug 14, 2026 |
| DV Trading LLC | Sell 100% | -$3.73M | $0 | 0.00% | Aug 14, 2026 |
| Great Point Partners LLC | New Buy | +$3.55M | $3.55M | 0.67% | Aug 14, 2026 |
| Seven Grand Managers, LLC | New Buy | +$3.55M | $3.55M | 0.14% | Aug 14, 2026 |
| HighVista Strategies LLC | Added 88.59% | +$3.29M | $7M | 1.60% | Aug 14, 2026 |
| ADAR1 Capital Management, LLC | Added 17.65% | +$2.95M | $19.7M | 0.90% | Aug 14, 2026 |
| Lighthouse Investment Partners, LLC | Reduce 73.33% | -$2.79M | $1.02M | 0.03% | Aug 14, 2026 |
| SummitTX Capital, L.P. | Sell 100% | -$2.69M | $0 | 0.00% | Aug 14, 2026 |
| Artia Global Partners LP | Added 244.98% | +$2.6M | $3.66M | 0.68% | Aug 14, 2026 |
| Sphera Funds Management Ltd. | Reduce 26.42% | -$2.06M | $5.72M | 0.75% | Aug 14, 2026 |
| Susquehanna Portfolio Strategies, LLC | Reduce 70.52% | -$1.76M | $734K | 0.01% | Aug 14, 2026 |
| Legato Capital Management LLC | Added 107.77% | +$1.7M | $3.29M | 0.27% | Aug 6, 2026 |
| Ishara Investments LP | New Buy | +$1.66M | $1.66M | 1.22% | Aug 14, 2026 |
| Erste Asset Management GmbH | New Buy | +$1.27M | $1.27M | 0.01% | Jul 28, 2026 |
| Tema ETFs LLC | Added 40.97% | +$895K | $3.08M | 0.10% | Jul 10, 2026 |
| Handelsbanken Fonder AB | New Buy | +$878K | $878K | 0.00% | Jul 10, 2026 |
| Wellington Management Group LLP | Reduce 11.31% | -$862K | $6.76M | 0.00% | Aug 14, 2026 |
| Tidal Investments LLC | Added 27.74% | +$669K | $3.08M | 0.01% | Aug 13, 2026 |
| Patient Square Capital LP | Added 6.25% | +$634K | $10.8M | 1.67% | Aug 12, 2026 |
| FORA Capital, LLC | Sell 100% | -$577K | $0 | 0.00% | Aug 13, 2026 |
| VANGUARD ASSET MANAGEMENT, Ltd | Added 45.04% | +$527K | $1.7M | 0.00% | Aug 13, 2026 |
| Diadema Partners LP | Added 3981.63% | +$495K | $508K | 0.06% | Aug 14, 2026 |
| Virtus Investment Advisers, LLC | Reduce 56.14% | -$461K | $360K | 0.08% | Aug 11, 2026 |
| Fox Run Management, L.L.C. | Reduce 56.92% | -$450K | $340K | 0.06% | Aug 4, 2026 |
| Bamco Inc | New Buy | +$381K | $381K | 0.00% | Aug 14, 2026 |
| Bridgefront Capital, LLC | Added 108.37% | +$319K | $614K | 0.16% | Aug 14, 2026 |
| Knott David M Jr | New Buy | +$314K | $314K | 0.17% | Aug 12, 2026 |
| Cinctive Capital Management LP | Reduce 4.99% | -$287K | $5.47M | 0.20% | Aug 14, 2026 |
| CenterBook Partners LP | New Buy | +$287K | $287K | 0.01% | Aug 11, 2026 |
| KLP Kapitalforvaltning As | Added 80.88% | +$279K | $624K | 0.00% | Aug 12, 2026 |
| Vanguard Investments Australia, Ltd. | Added 76.04% | +$276K | $639K | 0.00% | Aug 13, 2026 |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | New Buy | +$228K | $228K | 0.05% | Aug 13, 2026 |
| Xponance LLC | New Buy | +$214K | $214K | 0.00% | Aug 10, 2026 |
| Quarry LP | New Buy | +$205K | $205K | 0.02% | Aug 14, 2026 |
| Persistent Asset Partners Ltd | Added 42.79% | +$143K | $479K | 0.14% | Aug 7, 2026 |
| Quantinno Capital Management LP | Added 32.09% | +$106K | $438K | 0.00% | Aug 13, 2026 |
| KBC Group NV | Added 88.41% | +$43.2K | $92K | 0.00% | Aug 5, 2026 |
| China Universal Asset Management Co., Ltd. | Reduce 7.97% | -$42.6K | $492K | 0.03% | Jul 24, 2026 |
| Kemnay Advisory Services Inc. | New Buy | +$28.7K | $28.7K | 0.00% | Aug 14, 2026 |
| Axq Capital, LP | Reduce 5.05% | -$27.3K | $512K | 0.06% | Aug 6, 2026 |
| Profund Advisors LLC | Reduce 6.36% | -$26.6K | $392K | 0.01% | Aug 11, 2026 |
| State of New Jersey Common Pension Fund D | Reduce 2.92% | -$16.5K | $550K | 0.00% | Aug 4, 2026 |
| J.Safra Asset Management Corp | New Buy | +$15.2K | $15.2K | 0.00% | Aug 6, 2026 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | Reduce 25.83% | -$11.1K | $31.8K | 0.00% | Aug 13, 2026 |
| SMA Capital LLC | New Buy | +$10.4K | $10.4K | 0.00% | Aug 14, 2026 |
| Canada Pension Plan Investment Board | Added 0.65% | +$5.08K | $782K | 0.00% | Aug 14, 2026 |
| Optimize Financial Inc. | Reduce 0.35% | -$2.64K | $761K | 0.27% | Aug 27, 2026 |
| Jennison Associates LLC | Added 0.01% | +$1.98K | $15.7M | 0.01% | Aug 3, 2026 |
| Institute for Wealth Management, LLC. | New Buy | +$1.53K | $1.53K | 0.00% | Jul 28, 2026 |
| Versant Capital Management, Inc | Added 0.38% | +$305 | $80.2K | 0.01% | Jul 2, 2026 |
