| Siren, L.L.C. | Added 56.62% | +$45.6M | $126M | 2.55% | Aug 13, 2026 |
| Adage Capital Partners GP, L.L.C. | Reduce 45.30% | -$36.5M | $44.1M | 0.06% | Aug 14, 2026 |
| Logos Global Management LP | Reduce 72.22% | -$36.1M | $13.9M | 0.60% | Aug 14, 2026 |
| Driehaus Capital Management LLC | Reduce 70.38% | -$34.1M | $14.4M | 0.08% | Aug 14, 2026 |
| Pictet Asset Management Holding SA | Added 43.59% | +$32.3M | $106M | 0.10% | Jul 30, 2026 |
| Westfield Capital Management Co LP | Added 14.49% | +$31M | $245M | 0.80% | Aug 12, 2026 |
| Lord, Abbett & Co. LLC | Sell 100% | -$30.3M | $0 | 0.00% | Aug 14, 2026 |
| Primecap Management Co | Reduce 7.28% | -$27.6M | $352M | 0.21% | Aug 14, 2026 |
| Wellington Management Group LLP | Added 78.53% | +$23.9M | $54.3M | 0.01% | Aug 14, 2026 |
| Perceptive Advisors LLC | Added 8.95% | +$23.6M | $287M | 4.31% | Aug 14, 2026 |
| Duquesne Family Office LLC | New Buy | +$22.6M | $22.6M | 0.43% | Aug 14, 2026 |
| Hood River Capital Management LLC | Sell 100% | -$20.9M | $0 | 0.00% | Aug 14, 2026 |
| First Turn Management, LLC | New Buy | +$17.1M | $17.1M | 1.83% | Aug 14, 2026 |
| Nicholas Investment Partners, LP | New Buy | +$15.5M | $15.5M | 0.87% | Aug 14, 2026 |
| Kennedy Capital Management LLC | Added 193.56% | +$14.1M | $21.5M | 0.38% | Aug 14, 2026 |
| Segall Bryant & Hamill, LLC | New Buy | +$13.5M | $13.5M | 0.16% | Aug 12, 2026 |
| Longaeva Partners L.P. | New Buy | +$12.2M | $12.2M | 0.27% | Aug 14, 2026 |
| Capital World Investors | Added 91.41% | +$11.7M | $24.6M | 0.00% | Aug 12, 2026 |
| Sphera Funds Management Ltd. | New Buy | +$8.93M | $8.93M | 1.16% | Aug 14, 2026 |
| ADAR1 Capital Management, LLC | Reduce 35.61% | -$8.36M | $15.1M | 0.69% | Aug 14, 2026 |
| Braidwell LP | Added 22.70% | +$7.83M | $42.3M | 1.57% | Aug 14, 2026 |
| Capital Fund Management S.A. | New Buy | +$7.61M | $7.61M | 0.03% | Aug 13, 2026 |
| First Trust Advisors LP | Reduce 62.01% | -$5.89M | $3.61M | 0.00% | Aug 11, 2026 |
| Integral Health Asset Management, LLC | Reduce 8.33% | -$5.55M | $61.1M | 2.41% | Aug 14, 2026 |
| Polar Capital Holdings Plc | Added 2.97% | +$5.33M | $185M | 0.44% | Aug 14, 2026 |
| Canada Pension Plan Investment Board | New Buy | +$5.26M | $5.26M | 0.00% | Aug 14, 2026 |
| Cinctive Capital Management LP | New Buy | +$4.75M | $4.75M | 0.17% | Aug 14, 2026 |
| Sofinnova Investments, Inc. | Reduce 9.35% | -$4.67M | $45.3M | 2.34% | Aug 14, 2026 |
| Checkpoint Capital L.P. | Reduce 3.36% | -$4.57M | $132M | 33.79% | Aug 14, 2026 |
| Castleark Management LLC | Sell 100% | -$4.55M | $0 | 0.00% | Aug 14, 2026 |
| SummitTX Capital, L.P. | Reduce 23.67% | -$4.35M | $14M | 0.36% | Aug 14, 2026 |
| Harvest Investment Services, LLC | Sell 100% | -$4.22M | $0 | 0.00% | Aug 14, 2026 |
| Artisan Partners Limited Partnership | Reduce 9.18% | -$3.98M | $39.4M | 0.06% | Aug 13, 2026 |
| PFM Health Sciences, LP | Reduce 25.67% | -$3.89M | $11.3M | 0.97% | Aug 14, 2026 |
| Utah Retirement Systems | Sell 100% | -$3.67M | $0 | 0.00% | Aug 14, 2026 |
| Loomis Sayles & Co L P | Reduce 6.67% | -$3.44M | $48.2M | 0.06% | Aug 14, 2026 |
| Schroder Investment Management Group | Added 21.91% | +$3.17M | $17.7M | 0.01% | Aug 13, 2026 |
| Silvercrest Asset Management Group LLC | Added 56.61% | +$2.95M | $8.15M | 0.05% | Aug 14, 2026 |
| Harbor Capital Advisors, Inc. | Sell 100% | -$2.64M | $0 | 0.00% | Aug 7, 2026 |
| PDT Partners, LLC | Sell 100% | -$2.37M | $0 | 0.00% | Aug 14, 2026 |
| Rafferty Asset Management, LLC | Reduce 35.72% | -$1.99M | $3.58M | 0.01% | Aug 14, 2026 |
| Aberdeen Group plc | Added 19.64% | +$1.73M | $10.5M | 0.01% | Jul 31, 2026 |
| Picton Mahoney Asset Management | Added 30.79% | +$1.72M | $7.31M | 0.05% | Aug 13, 2026 |
| Susquehanna Portfolio Strategies, LLC | New Buy | +$1.23M | $1.23M | 0.02% | Aug 14, 2026 |
| Texas Treasury Safekeeping Trust Co | Sell 100% | -$1.07M | $0 | 0.00% | Aug 14, 2026 |
| Exome Asset Management LLC | Reduce 20.63% | -$930K | $3.58M | 2.21% | Aug 14, 2026 |
| CenterBook Partners LP | Reduce 78.12% | -$783K | $219K | 0.01% | Aug 11, 2026 |
| Profund Advisors LLC | Reduce 26.25% | -$664K | $1.87M | 0.05% | Aug 11, 2026 |
| Virtus Investment Advisers, LLC | Added 77.00% | +$636K | $1.46M | 0.34% | Aug 11, 2026 |
| NEXTBio Capital Management LP | Added 4.51% | +$631K | $14.6M | 6.73% | Aug 14, 2026 |
| Teachers Retirement System of the State of Kentucky | New Buy | +$622K | $622K | 0.00% | Aug 12, 2026 |
| Guggenheim Capital LLC | Reduce 33.65% | -$618K | $1.22M | 0.01% | Aug 12, 2026 |
| Silverarc Capital Management, LLC | Added 1.78% | +$606K | $34.6M | 3.59% | Aug 13, 2026 |
| IMC-Chicago, LLC | Sell 100% | -$582K | $0 | 0.00% | Aug 6, 2026 |
| Aspiriant, LLC | Reduce 15.29% | -$560K | $3.1M | 0.08% | Jul 20, 2026 |
| Fulcrum Asset Management LLP | New Buy | +$556K | $556K | 0.06% | Aug 18, 2026 |
| Inceptionr LLC | Added 113.59% | +$552K | $1.04M | 0.25% | Aug 11, 2026 |
| Allstate Corp | New Buy | +$547K | $547K | 0.01% | Aug 13, 2026 |
| Axiom Investors LLC | Reduce 5.31% | -$541K | $9.65M | 0.08% | Aug 12, 2026 |
| Campbell & CO Investment Adviser LLC | Sell 100% | -$518K | $0 | 0.00% | Aug 3, 2026 |
| Blueshift Asset Management, LLC | Sell 100% | -$503K | $0 | 0.00% | Aug 14, 2026 |
| Matisse Capital | New Buy | +$444K | $444K | 0.18% | Aug 12, 2026 |
| Sound View Wealth Advisors Group, LLC | New Buy | +$409K | $409K | 0.03% | Aug 11, 2026 |
| VANGUARD ASSET MANAGEMENT, Ltd | Added 7.22% | +$399K | $5.92M | 0.00% | Aug 13, 2026 |
| Inspire Investing, LLC | New Buy | +$379K | $379K | 0.02% | Aug 12, 2026 |
| Yorktown Management & Research Co Inc | New Buy | +$366K | $366K | 0.22% | Jul 23, 2026 |
| HighVista Strategies LLC | Reduce 18.69% | -$349K | $1.52M | 0.35% | Aug 14, 2026 |
| Fox Run Management, L.L.C. | Sell 100% | -$348K | $0 | 0.00% | Aug 4, 2026 |
| Rock Springs Capital Management LP | Added 0.41% | +$316K | $76.9M | 3.75% | Aug 14, 2026 |
| Knights of Columbus Asset Advisors LLC | Added 15.74% | +$272K | $2M | 0.10% | Jul 31, 2026 |
| Ethic Inc. | Sell 100% | -$261K | $0 | 0.00% | Jul 29, 2026 |
| Toth Financial Advisory Corp | Reduce 22.00% | -$244K | $866K | 0.08% | Jul 14, 2026 |
| Praxis Investment Management Inc | New Buy | +$228K | $228K | 0.01% | Aug 4, 2026 |
| PSP Research LLC | New Buy | +$222K | $222K | 0.12% | Jul 9, 2026 |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | Reduce 4.43% | -$216K | $4.66M | 0.00% | Aug 13, 2026 |
| Cornerstone Partners Capital Management, LLC | Sell 100% | -$214K | $0 | 0.00% | Jul 30, 2026 |
| nVerses Capital, LLC | New Buy | +$212K | $212K | 0.33% | Aug 4, 2026 |
| State of New Jersey Common Pension Fund D | Reduce 8.88% | -$191K | $1.96M | 0.01% | Aug 4, 2026 |
| E Fund Management Co., Ltd. | Reduce 26.38% | -$189K | $528K | 0.01% | Aug 11, 2026 |
| First Light Asset Management, LLC | Reduce 1.62% | -$157K | $9.52M | 0.58% | Aug 14, 2026 |
| Handelsbanken Fonder AB | Added 7.99% | +$155K | $2.1M | 0.01% | Jul 10, 2026 |
| Northwest & Ethical Investments L.P. | Reduce 55.84% | -$153K | $121K | 0.00% | Aug 13, 2026 |
| Bridgefront Capital, LLC | Reduce 9.71% | -$135K | $1.25M | 0.33% | Aug 14, 2026 |
| China Universal Asset Management Co., Ltd. | Reduce 9.91% | -$133K | $1.21M | 0.07% | Jul 24, 2026 |
| E. Ohman J:or Asset Management AB | Added 25.27% | +$124K | $613K | 0.01% | Jul 10, 2026 |
| Wedge Capital Management L L P | Reduce 4.54% | -$124K | $2.6M | 0.04% | Jul 10, 2026 |
| Avior Wealth Management, LLC | Added 16.99% | +$87.7K | $604K | 0.02% | Jul 7, 2026 |
| Vanguard Investments Australia, Ltd. | Added 5.31% | +$82.1K | $1.63M | 0.00% | Aug 13, 2026 |
| CIBC Asset Management Inc | Reduce 25.84% | -$81.7K | $234K | 0.00% | Aug 3, 2026 |
| Gotham Asset Management, LLC | Added 13.78% | +$74.2K | $612K | 0.00% | Aug 14, 2026 |
| EFG International AG | Reduce 1.86% | -$70.7K | $3.73M | 0.07% | Aug 14, 2026 |
| Summit Securities Group LLC | New Buy | +$60.3K | $60.3K | 0.01% | Aug 3, 2026 |
| Pacer Advisors, Inc. | New Buy | +$60K | $60K | 0.00% | Aug 13, 2026 |
| Bayforest Capital Ltd | New Buy | +$56.7K | $56.7K | 0.05% | Aug 5, 2026 |
| Opaleye Management Inc. | Reduce 0.41% | -$55.5K | $13.6M | 1.23% | Aug 14, 2026 |
| Exchange Traded Concepts, LLC | Reduce 5.87% | -$55.2K | $884K | 0.00% | Aug 11, 2026 |
| Xponance LLC | Added 9.52% | +$52.7K | $607K | 0.00% | Aug 10, 2026 |
| DNB Asset Management AS | Added 2.41% | +$30K | $1.27M | 0.00% | Aug 11, 2026 |
| Swiss Life Asset Management Ltd | Added 5.93% | +$22K | $393K | 0.00% | Jul 29, 2026 |
| Ensign Peak Advisors, Inc | Reduce 3.89% | -$16.7K | $412K | 0.00% | Aug 14, 2026 |
