| RTW Investments, LP | New Buy | +$86.3M | $86.3M | 0.74% | Aug 14, 2026 |
| Paradigm Biocapital Advisors LP | Sell 100% | -$26.3M | $0 | 0.00% | Aug 14, 2026 |
| Deep Track Capital, LP | Added 10.75% | +$24.7M | $254M | 3.70% | Aug 14, 2026 |
| Siren, L.L.C. | Reduce 34.30% | -$24.5M | $46.9M | 0.95% | Aug 13, 2026 |
| Davern Capital Partners, LP | Added 252.72% | +$17.2M | $23.9M | 4.08% | Aug 13, 2026 |
| Deerfield Management Company, L.P. | Added 41.41% | +$17.1M | $58.3M | 0.61% | Aug 14, 2026 |
| Parkman Healthcare Partners LLC | Added 109.25% | +$13.6M | $26.1M | 2.67% | Aug 14, 2026 |
| Aberdeen Group plc | Added 63.32% | +$13.3M | $34.3M | 0.05% | Jul 31, 2026 |
| Pentwater Capital Management LP | Sell 100% | -$11.8M | $0 | 0.00% | Aug 14, 2026 |
| Sio Capital Management, LLC | Sell 100% | -$10.1M | $0 | 0.00% | Aug 14, 2026 |
| NEXTBio Capital Management LP | Added 134.54% | +$9.62M | $16.8M | 7.71% | Aug 14, 2026 |
| Holocene Advisors, LP | Sell 100% | -$7.66M | $0 | 0.00% | Aug 14, 2026 |
| Voloridge Investment Management, LLC | Reduce 55.96% | -$7.66M | $6.03M | 0.03% | Aug 14, 2026 |
| CenterBook Partners LP | Added 597.04% | +$6.8M | $7.94M | 0.39% | Aug 11, 2026 |
| TCG Crossover Management, LLC | Sell 100% | -$6.77M | $0 | 0.00% | Aug 14, 2026 |
| Wellington Management Group LLP | Added 1.64% | +$6.39M | $396M | 0.07% | Aug 14, 2026 |
| Capitolis Liquid Global Markets LLC | Reduce 9.57% | -$5.91M | $55.9M | 0.24% | Aug 13, 2026 |
| Cormorant Asset Management, LP | Reduce 57.14% | -$5.37M | $4.03M | 0.21% | Aug 14, 2026 |
| BVF Inc | Reduce 2.67% | -$4.97M | $181M | 4.62% | Aug 14, 2026 |
| Susquehanna Portfolio Strategies, LLC | Added 146.13% | +$4.75M | $7.99M | 0.13% | Aug 14, 2026 |
| Birchview Capital, LP | Reduce 76.00% | -$4.08M | $1.29M | 0.60% | Aug 14, 2026 |
| Adage Capital Partners GP, L.L.C. | New Buy | +$4.03M | $4.03M | 0.01% | Aug 14, 2026 |
| Diadema Partners LP | Sell 100% | -$3.48M | $0 | 0.00% | Aug 14, 2026 |
| Jones Hill Capital LP | Reduce 59.67% | -$3.22M | $2.18M | 0.46% | Aug 13, 2026 |
| Eversept Partners, LP | Added 42.21% | +$3.13M | $10.5M | 0.55% | Aug 14, 2026 |
| Pacific Heights Asset Management LLC | Added 6.67% | +$2.68M | $42.9M | 1.36% | Aug 17, 2026 |
| Healthcare of Ontario Pension Plan Trust Fund | Reduce 10.47% | -$2.63M | $22.5M | 0.03% | Aug 13, 2026 |
| Pier Capital, LLC | Sell 100% | -$2.29M | $0 | 0.00% | Aug 5, 2026 |
| ArrowMark Colorado Holdings LLC | Reduce 19.99% | -$2.02M | $8.08M | 0.34% | Aug 13, 2026 |
| Flax Pond Capital, LLC | Added 102.78% | +$1.88M | $3.72M | 1.38% | Aug 14, 2026 |
| PFM Health Sciences, LP | Reduce 27.56% | -$1.87M | $4.91M | 0.42% | Aug 14, 2026 |
| Cinctive Capital Management LP | Added 369.10% | +$1.73M | $2.19M | 0.08% | Aug 14, 2026 |
| Driehaus Capital Management LLC | Reduce 1.53% | -$1.3M | $83.4M | 0.48% | Aug 14, 2026 |
| Platinum Investment Management Ltd | Added 35.14% | +$1.26M | $4.85M | 1.19% | Aug 13, 2026 |
| Sphera Funds Management Ltd. | Reduce 43.70% | -$1.19M | $1.53M | 0.20% | Aug 14, 2026 |
| Jefferies Financial Group Inc. | Reduce 35.10% | -$1.18M | $2.18M | 0.01% | Aug 17, 2026 |
| Catalio Capital Management, LP | Added 8.29% | +$1.14M | $14.8M | 2.79% | Aug 14, 2026 |
| Avidity Partners Management LP | Added 25.64% | +$1.07M | $5.26M | 0.84% | Aug 14, 2026 |
| Handelsbanken Fonder AB | New Buy | +$1.04M | $1.04M | 0.00% | Jul 10, 2026 |
| Nomura Asset Management International Inc. | Added 14.26% | +$1.03M | $8.22M | 0.01% | Aug 14, 2026 |
| Seven Fleet Capital Management LP | Added 197.78% | +$957K | $1.44M | 0.24% | Aug 17, 2026 |
| ADAR1 Capital Management, LLC | New Buy | +$939K | $939K | 0.04% | Aug 14, 2026 |
| Rhenman & Partners Asset Management AB | Added 13.27% | +$912K | $7.79M | 0.74% | Aug 13, 2026 |
| Persistent Asset Partners Ltd | Sell 100% | -$880K | $0 | 0.00% | Aug 7, 2026 |
| Alps Advisors Inc | Added 24.57% | +$760K | $3.86M | 0.02% | Jul 29, 2026 |
| Gladstone Institutional Advisory LLC | New Buy | +$712K | $712K | 0.02% | Jul 27, 2026 |
| Fulcrum Asset Management LLP | New Buy | +$685K | $685K | 0.07% | Aug 18, 2026 |
| B Group, Inc. | Added 9.80% | +$671K | $7.51M | 3.53% | Aug 14, 2026 |
| MML Investors Services, LLC | Added 84.35% | +$629K | $1.37M | 0.00% | Aug 7, 2026 |
| Fox Run Management, L.L.C. | New Buy | +$578K | $578K | 0.10% | Aug 4, 2026 |
| IMC-Chicago, LLC | New Buy | +$463K | $463K | 0.00% | Aug 6, 2026 |
| Axq Capital, LP | Sell 100% | -$382K | $0 | 0.00% | Aug 6, 2026 |
| HighVista Strategies LLC | Added 5.55% | +$369K | $7.02M | 1.60% | Aug 14, 2026 |
| EntryPoint Capital, LLC | New Buy | +$329K | $329K | 0.08% | Aug 13, 2026 |
| Banque Pictet & Cie SA | Reduce 12.22% | -$324K | $2.33M | 0.01% | Jul 24, 2026 |
| Exchange Traded Concepts, LLC | Added 21.26% | +$290K | $1.65M | 0.01% | Aug 11, 2026 |
| Jain Global LLC | Sell 100% | -$278K | $0 | 0.00% | Aug 14, 2026 |
| Peregrine Capital Management LLC | Reduce 5.03% | -$262K | $4.95M | 0.16% | Jul 17, 2026 |
| Capital Fund Management S.A. | Added 14.94% | +$260K | $2M | 0.01% | Aug 13, 2026 |
| Private Capital Advisors, Inc. | Reduce 13.46% | -$248K | $1.6M | 0.14% | Jul 24, 2026 |
| DCF Advisers, LLC | Added 16.73% | +$247K | $1.72M | 0.30% | Aug 10, 2026 |
| Tidal Investments LLC | Sell 100% | -$224K | $0 | 0.00% | Aug 13, 2026 |
| Prospera Financial Services Inc | New Buy | +$220K | $220K | 0.00% | Jul 15, 2026 |
| Virtus Investment Advisers, LLC | Added 87.50% | +$191K | $409K | 0.10% | Aug 11, 2026 |
| Quadcap Wealth Management, LLC | Added 61.45% | +$156K | $410K | 0.04% | Jul 31, 2026 |
| Independent Advisor Alliance | Reduce 38.97% | -$156K | $244K | 0.01% | Aug 12, 2026 |
| DNB Asset Management AS | Added 31.64% | +$139K | $579K | 0.00% | Aug 11, 2026 |
| PSquared Asset Management AG | Added 6.29% | +$118K | $2M | 0.65% | Aug 17, 2026 |
| Bellevue Group AG | Reduce 30.00% | -$110K | $256K | 0.01% | Aug 14, 2026 |
| Nano Cap New Millennium Growth Fund L P | Added 133.33% | +$107K | $188K | 0.14% | Aug 14, 2026 |
| China Universal Asset Management Co., Ltd. | Reduce 10.24% | -$75.9K | $666K | 0.04% | Jul 24, 2026 |
| E. Ohman J:or Asset Management AB | Reduce 28.91% | -$70.1K | $172K | 0.00% | Jul 10, 2026 |
| SmartHarvest Portfolios, LLC | Added 9.63% | +$46.8K | $533K | 0.17% | Aug 4, 2026 |
| TrueMark Investments, LLC | Reduce 2.26% | -$41.7K | $1.8M | 0.23% | Jul 22, 2026 |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | Added 10.86% | +$24.4K | $249K | 0.05% | Aug 13, 2026 |
| Quarry LP | New Buy | +$13.1K | $13.1K | 0.00% | Aug 14, 2026 |
| Godfrey Financial Associates, Inc. | New Buy | +$13.1K | $13.1K | 0.01% | Aug 11, 2026 |
| Assetmark, Inc | Added 7.15% | +$9.77K | $146K | 0.00% | Jul 30, 2026 |
| Rock Springs Capital Management LP | Added 0.02% | +$5.37K | $34.4M | 1.68% | Aug 14, 2026 |
| Farmers & Merchants Investments Inc | Sell 100% | -$4.82K | $0 | 0.00% | Jul 20, 2026 |
| Huntington National Bank | Added 3850.00% | +$4.13K | $4.24K | 0.00% | Aug 13, 2026 |
| Gilbert & Cook, Inc. | Reduce 0.28% | -$1.4K | $492K | 0.06% | Jul 28, 2026 |
| Ares Financial Consulting, LLC | New Buy | +$1.07K | $1.07K | 0.00% | Jul 9, 2026 |
| Bessemer Group Inc | New Buy | +$1K | $1K | 0.00% | Aug 12, 2026 |
