| Helikon Investments Ltd | Added 175.05% | +$236M | $371M | 11.10% | Aug 11, 2026 |
| Ra Capital Management, L.P. | New Buy | +$151M | $151M | 1.31% | Aug 14, 2026 |
| Vestal Point Capital, LP | Added 56.63% | +$113M | $313M | 7.32% | Aug 14, 2026 |
| Lord, Abbett & Co. LLC | Reduce 98.89% | -$113M | $1.27M | 0.00% | Aug 14, 2026 |
| Baker Bros. Advisors LP | Sell 100% | -$97.5M | $0 | 0.00% | Aug 14, 2026 |
| Paradigm Biocapital Advisors LP | Sell 100% | -$86M | $0 | 0.00% | Aug 14, 2026 |
| Siren, L.L.C. | New Buy | +$76.8M | $76.8M | 1.55% | Aug 13, 2026 |
| TCG Crossover Management, LLC | Reduce 7.30% | -$63.1M | $801M | 19.24% | Aug 14, 2026 |
| ADAR1 Capital Management, LLC | Added 29.46% | +$54.7M | $240M | 11.01% | Aug 14, 2026 |
| Summit Partners Public Asset Management, LLC | New Buy | +$54.6M | $54.6M | 0.96% | Aug 14, 2026 |
| Boxer Capital Management, LLC | Added 202.50% | +$54M | $80.6M | 6.07% | Aug 14, 2026 |
| Pictet Asset Management Holding SA | Added 375.22% | +$51.8M | $65.6M | 0.06% | Jul 30, 2026 |
| Adage Capital Partners GP, L.L.C. | Reduce 93.38% | -$49.8M | $3.53M | 0.01% | Aug 14, 2026 |
| Logos Global Management LP | Added 51.70% | +$46.5M | $136M | 5.87% | Aug 14, 2026 |
| Octagon Capital Advisors LP | Added 46.68% | +$42.1M | $132M | 11.89% | Aug 14, 2026 |
| Melqart Asset Management (UK) Ltd | New Buy | +$40.9M | $40.9M | 3.90% | Aug 14, 2026 |
| Ikarian Capital, LLC | Added 470.20% | +$35.7M | $43.4M | 4.67% | Aug 14, 2026 |
| Perceptive Advisors LLC | Reduce 77.50% | -$34M | $9.86M | 0.15% | Aug 14, 2026 |
| Two Seas Capital LP | New Buy | +$32.6M | $32.6M | 0.65% | Aug 12, 2026 |
| MPM Bioimpact LLC | Added 213.56% | +$30.5M | $44.8M | 2.73% | Aug 14, 2026 |
| Great Point Partners LLC | New Buy | +$27.2M | $27.2M | 5.15% | Aug 14, 2026 |
| Kite Lake Capital Management (UK) LLP | Added 200.60% | +$26.7M | $40.1M | 13.82% | Aug 14, 2026 |
| Western Standard LLC | New Buy | +$26.7M | $26.7M | 9.03% | Aug 10, 2026 |
| Vivo Capital, LLC | Added 73.21% | +$23.4M | $55.3M | 5.05% | Aug 14, 2026 |
| Holocene Advisors, LP | Added 61.86% | +$21.3M | $55.8M | 0.13% | Aug 14, 2026 |
| Silverarc Capital Management, LLC | Reduce 43.94% | -$17.7M | $22.6M | 2.35% | Aug 13, 2026 |
| APEIRON CAPITAL Ltd | New Buy | +$17.4M | $17.4M | 11.18% | Aug 6, 2026 |
| Nantahala Capital Management, LLC | Added 94.93% | +$17.4M | $35.6M | 0.59% | Aug 19, 2026 |
| Ensign Peak Advisors, Inc | Reduce 20.16% | -$17M | $67.2M | 0.11% | Aug 14, 2026 |
| Wellington Management Group LLP | New Buy | +$16.4M | $16.4M | 0.00% | Aug 14, 2026 |
| DG Capital Management, LLC | New Buy | +$16.3M | $16.3M | 3.43% | Aug 12, 2026 |
| Evergreen Quality Fund GP, Ltd. | Sell 100% | -$16.1M | $0 | 0.00% | Aug 14, 2026 |
| Farallon Capital Management, L.L.C. | Added 6000.00% | +$16M | $16.3M | 0.08% | Aug 14, 2026 |
| Sio Capital Management, LLC | Sell 100% | -$15.1M | $0 | 0.00% | Aug 14, 2026 |
| Darwin Global Management, Ltd. | Added 4.41% | +$14.7M | $348M | 9.26% | Aug 14, 2026 |
| Squadron Capital Management LLC | Sell 100% | -$14.5M | $0 | 0.00% | Aug 14, 2026 |
| Caligan Partners LP | Added 6.57% | +$12.8M | $208M | 9.77% | Aug 14, 2026 |
| Aberdeen Group plc | Added 21.05% | +$12.1M | $69.6M | 0.10% | Jul 31, 2026 |
| Diadema Partners LP | Added 115.48% | +$11.6M | $21.6M | 2.73% | Aug 14, 2026 |
| Patient Square Capital LP | Added 70.32% | +$11.4M | $27.5M | 4.26% | Aug 12, 2026 |
| Cormorant Asset Management, LP | Reduce 11.18% | -$11.3M | $90M | 4.61% | Aug 14, 2026 |
| Artia Global Partners LP | Reduce 14.03% | -$11.2M | $68.8M | 12.70% | Aug 14, 2026 |
| Findell Capital Management LLC | Added 76.19% | +$10.7M | $24.7M | 3.47% | Aug 14, 2026 |
| Nicholas Investment Partners, LP | Sell 100% | -$10M | $0 | 0.00% | Aug 14, 2026 |
| Affinity Asset Advisors, LLC | Reduce 18.52% | -$9.99M | $44M | 1.99% | Aug 13, 2026 |
| Eventide Asset Management, LLC | Added 23.20% | +$9.91M | $52.6M | 0.70% | Aug 14, 2026 |
| Nwi Management LP | New Buy | +$9.6M | $9.6M | 0.44% | Aug 14, 2026 |
| Seven Fleet Capital Management LP | Added 158.60% | +$9.1M | $14.8M | 2.45% | Aug 17, 2026 |
| Davern Capital Partners, LP | Sell 100% | -$8.7M | $0 | 0.00% | Aug 13, 2026 |
| SummitTX Capital, L.P. | New Buy | +$8.69M | $8.69M | 0.22% | Aug 14, 2026 |
| Apis Capital Advisors, LLC | Reduce 42.55% | -$7.3M | $9.86M | 0.96% | Aug 14, 2026 |
| Voleon Capital Management LP | Reduce 73.26% | -$7.2M | $2.63M | 0.05% | Aug 14, 2026 |
| Quinn Opportunity Partners LLC | Added 312.78% | +$6.67M | $8.8M | 0.41% | Aug 14, 2026 |
| Exome Asset Management LLC | New Buy | +$6.25M | $6.25M | 3.85% | Aug 14, 2026 |
| Erste Asset Management GmbH | Added 120.00% | +$5.77M | $10.6M | 0.08% | Jul 28, 2026 |
| Militia Capital Management LLC | Sell 100% | -$5.68M | $0 | 0.00% | Aug 12, 2026 |
| Maverick Capital Ltd | New Buy | +$5.33M | $5.33M | 0.05% | Aug 14, 2026 |
| Seven Grand Managers, LLC | Added 80.00% | +$5.33M | $12M | 0.48% | Aug 14, 2026 |
| Longaeva Partners L.P. | New Buy | +$5.33M | $5.33M | 0.12% | Aug 14, 2026 |
| Readystate Asset Management LP | Added 19.56% | +$5.26M | $32.2M | 1.10% | Aug 14, 2026 |
| Catalio Capital Management, LP | Sell 100% | -$5.25M | $0 | 0.00% | Aug 14, 2026 |
| Alpine Associates Management Inc. | New Buy | +$5.13M | $5.13M | 0.32% | Aug 6, 2026 |
| Knoll Capital Management, LLC | New Buy | +$4.66M | $4.66M | 2.60% | Aug 14, 2026 |
| Nomura Asset Management International Inc. | New Buy | +$4M | $4M | 0.01% | Aug 14, 2026 |
| K2 Principal Fund, L.P. | Reduce 54.59% | -$3.91M | $3.25M | 0.24% | Aug 7, 2026 |
| Ally Bridge Group (NY) LLC | Sell 100% | -$3.75M | $0 | 0.00% | Aug 14, 2026 |
| Picton Mahoney Asset Management | New Buy | +$3.69M | $3.69M | 0.03% | Aug 13, 2026 |
| Atle Fund Management AB | Added 84.14% | +$3.54M | $7.75M | 2.09% | Jul 24, 2026 |
| RTW Investments, LP | New Buy | +$3.52M | $3.52M | 0.03% | Aug 14, 2026 |
| Quantinno Capital Management LP | New Buy | +$3.39M | $3.39M | 0.00% | Aug 13, 2026 |
| CenterBook Partners LP | Added 300.79% | +$3.38M | $4.51M | 0.22% | Aug 11, 2026 |
| PSquared Asset Management AG | Added 154.32% | +$3.33M | $5.49M | 1.79% | Aug 17, 2026 |
| First Turn Management, LLC | Added 5.16% | +$3.2M | $65.3M | 6.98% | Aug 14, 2026 |
| Burkehill Global Management, LP | New Buy | +$3.2M | $3.2M | 0.12% | Aug 14, 2026 |
| Saturn V Capital Management LP | Reduce 4.39% | -$3.18M | $69.1M | 9.91% | Aug 14, 2026 |
| Monimus Capital Management, LP | New Buy | +$2.88M | $2.88M | 0.67% | Aug 14, 2026 |
| Persistent Asset Partners Ltd | Added 93.78% | +$2.85M | $5.9M | 1.76% | Aug 7, 2026 |
| Rosalind Advisors, Inc. | New Buy | +$2.78M | $2.78M | 1.03% | Aug 14, 2026 |
| Caxton Associates LLP | Sell 100% | -$2.76M | $0 | 0.00% | Aug 14, 2026 |
| Eversept Partners, LP | Reduce 2.20% | -$2.74M | $122M | 6.32% | Aug 14, 2026 |
| Beartown Capital Management, LLC | New Buy | +$2.67M | $2.67M | 1.17% | Aug 14, 2026 |
| Diversify Advisory Services, LLC | New Buy | +$2.66M | $2.66M | 0.04% | Aug 10, 2026 |
| IMC-Chicago, LLC | Reduce 17.67% | -$2.5M | $11.6M | 0.00% | Aug 6, 2026 |
| Resolute Capital Asset Partners LLC | New Buy | +$2.33M | $2.33M | 1.00% | Aug 14, 2026 |
| Birchview Capital, LP | New Buy | +$2.27M | $2.27M | 1.06% | Aug 14, 2026 |
| Cinctive Capital Management LP | Sell 100% | -$2.23M | $0 | 0.00% | Aug 14, 2026 |
| PFM Health Sciences, LP | Added 62.26% | +$2.21M | $5.77M | 0.49% | Aug 14, 2026 |
| SIH Partners, LLLP | New Buy | +$2.07M | $2.07M | 0.01% | Aug 14, 2026 |
| Jennison Associates LLC | Reduce 6.65% | -$1.87M | $26.2M | 0.02% | Aug 3, 2026 |
| Summit Securities Group LLC | New Buy | +$1.87M | $1.87M | 0.18% | Aug 3, 2026 |
| Schroder Investment Management Group | Sell 100% | -$1.82M | $0 | 0.00% | Aug 13, 2026 |
| Fifth Lane Capital, LP | Sell 100% | -$1.77M | $0 | 0.00% | Aug 6, 2026 |
| Nan Fung Trinity (Hk) Ltd | Added 10.19% | +$1.75M | $18.9M | 1.87% | Jul 24, 2026 |
| Westfield Capital Management Co LP | Reduce 0.99% | -$1.75M | $175M | 0.57% | Aug 12, 2026 |
| OMERS ADMINISTRATION Corp | New Buy | +$1.73M | $1.73M | 0.01% | Aug 13, 2026 |
| Banque Pictet & Cie SA | Sell 100% | -$1.67M | $0 | 0.00% | Jul 24, 2026 |
| E Fund Management Co., Ltd. | Sell 100% | -$1.53M | $0 | 0.00% | Aug 11, 2026 |
| Velan Capital Investment Management LP | Reduce 14.77% | -$1.52M | $8.75M | 5.33% | Aug 14, 2026 |
| Kennedy Capital Management LLC | Added 119.25% | +$1.39M | $2.56M | 0.05% | Aug 14, 2026 |
| Progeny 3, Inc. | Sell 100% | -$1.36M | $0 | 0.00% | Aug 14, 2026 |
