| Deerfield Management Company, L.P. | Reduce 44.65% | -$156M | $194M | 2.02% | Aug 14, 2026 |
| Polar Capital Holdings Plc | New Buy | +$125M | $125M | 0.30% | Aug 14, 2026 |
| RTW Investments, LP | Reduce 57.70% | -$122M | $89.4M | 0.76% | Aug 14, 2026 |
| Holocene Advisors, LP | Reduce 98.54% | -$85.8M | $1.27M | 0.00% | Aug 14, 2026 |
| Vestal Point Capital, LP | Sell 100% | -$47.4M | $0 | 0.00% | Aug 14, 2026 |
| Sofinnova Investments, Inc. | Reduce 51.02% | -$41.7M | $40.1M | 2.07% | Aug 14, 2026 |
| Deep Track Capital, LP | Added 100.00% | +$38.7M | $77.4M | 1.13% | Aug 14, 2026 |
| Logos Global Management LP | New Buy | +$34.8M | $34.8M | 1.50% | Aug 14, 2026 |
| Wellington Management Group LLP | Added 21.39% | +$29.6M | $168M | 0.03% | Aug 14, 2026 |
| Saturn V Capital Management LP | Sell 100% | -$24.1M | $0 | 0.00% | Aug 14, 2026 |
| Pictet Asset Management Holding SA | Added 33.06% | +$23M | $92.6M | 0.09% | Jul 30, 2026 |
| Massachusetts Financial Services Co | Added 127.41% | +$22.2M | $39.6M | 0.01% | Aug 3, 2026 |
| Eversept Partners, LP | New Buy | +$19M | $19M | 0.98% | Aug 14, 2026 |
| Segall Bryant & Hamill, LLC | New Buy | +$16.3M | $16.3M | 0.19% | Aug 12, 2026 |
| Vivo Capital, LLC | Sell 100% | -$16.3M | $0 | 0.00% | Aug 14, 2026 |
| Kynam Capital Management, LP | Reduce 9.17% | -$14.3M | $142M | 7.84% | Aug 14, 2026 |
| Ikarian Capital, LLC | New Buy | +$14.3M | $14.3M | 1.54% | Aug 14, 2026 |
| Venrock Adviser, LLC | Reduce 17.89% | -$13.8M | $63.6M | 1.93% | Aug 14, 2026 |
| Burkehill Global Management, LP | Reduce 51.85% | -$13.5M | $12.6M | 0.45% | Aug 14, 2026 |
| First Turn Management, LLC | Reduce 36.42% | -$13.4M | $23.3M | 2.49% | Aug 14, 2026 |
| Longaeva Partners L.P. | Sell 100% | -$12.9M | $0 | 0.00% | Aug 14, 2026 |
| Affinity Asset Advisors, LLC | Reduce 40.00% | -$11.6M | $17.4M | 0.79% | Aug 13, 2026 |
| Lord, Abbett & Co. LLC | Added 7.85% | +$9.67M | $133M | 0.38% | Aug 14, 2026 |
| Nantahala Capital Management, LLC | Sell 100% | -$9.62M | $0 | 0.00% | Aug 19, 2026 |
| Nwi Management LP | Reduce 50.00% | -$9.35M | $9.35M | 0.43% | Aug 14, 2026 |
| Hennion & Walsh Asset Management, Inc. | Reduce 59.64% | -$7.53M | $5.1M | 0.15% | Jul 8, 2026 |
| Patient Square Capital LP | Reduce 28.69% | -$6.62M | $16.4M | 2.55% | Aug 12, 2026 |
| Diadema Partners LP | Added 52.95% | +$6.61M | $19.1M | 2.41% | Aug 14, 2026 |
| Fred Alger Management, LLC | Reduce 13.46% | -$6.46M | $41.5M | 0.14% | Aug 14, 2026 |
| Commodore Capital LP | Added 5.61% | +$6.27M | $118M | 7.03% | Aug 14, 2026 |
| Silvercrest Asset Management Group LLC | New Buy | +$6.17M | $6.17M | 0.04% | Aug 14, 2026 |
| Parkman Healthcare Partners LLC | Added 153.05% | +$5.93M | $9.81M | 1.00% | Aug 14, 2026 |
| Integral Health Asset Management, LLC | Reduce 42.86% | -$5.81M | $7.74M | 0.31% | Aug 14, 2026 |
| Siren, L.L.C. | Added 8.78% | +$5.81M | $72M | 1.46% | Aug 13, 2026 |
| J. Goldman & Co LP | Reduce 18.16% | -$5.48M | $24.7M | 0.64% | Aug 14, 2026 |
| Jefferies Financial Group Inc. | Added 238.57% | +$5.13M | $7.28M | 0.05% | Aug 17, 2026 |
| Aberdeen Group plc | Added 44.20% | +$4.66M | $15.2M | 0.02% | Jul 31, 2026 |
| Swedbank AB | New Buy | +$4.58M | $4.58M | 0.00% | Jul 15, 2026 |
| Superstring Capital Management LP | Added 52.46% | +$4.57M | $13.3M | 8.39% | Aug 14, 2026 |
| Ensign Peak Advisors, Inc | Reduce 20.17% | -$4.47M | $17.7M | 0.03% | Aug 14, 2026 |
| SummitTX Capital, L.P. | Reduce 38.82% | -$4.41M | $6.96M | 0.18% | Aug 14, 2026 |
| Rock Springs Capital Management LP | Reduce 17.34% | -$4.19M | $20M | 0.97% | Aug 14, 2026 |
| Cormorant Asset Management, LP | Reduce 50.00% | -$3.87M | $3.87M | 0.20% | Aug 14, 2026 |
| Bleichroeder LP | New Buy | +$3.87M | $3.87M | 0.69% | Aug 13, 2026 |
| Nicholas Investment Partners, LP | Sell 100% | -$3.66M | $0 | 0.00% | Aug 14, 2026 |
| TCG Crossover Management, LLC | Reduce 1.87% | -$3.58M | $188M | 4.52% | Aug 14, 2026 |
| EFG International AG | New Buy | +$3.4M | $3.4M | 0.06% | Aug 14, 2026 |
| Pier Capital, LLC | Added 86.52% | +$3.39M | $7.31M | 0.97% | Aug 5, 2026 |
| Sector Gamma As | Sell 100% | -$3.08M | $0 | 0.00% | Aug 12, 2026 |
| Squadron Capital Management LLC | Added 9.84% | +$3M | $33.5M | 10.39% | Aug 14, 2026 |
| Public Employees Retirement Association of Colorado | Added 435.41% | +$2.69M | $3.3M | 0.01% | Aug 11, 2026 |
| Exome Asset Management LLC | Reduce 24.42% | -$2.63M | $8.15M | 5.03% | Aug 14, 2026 |
| Tema ETFs LLC | Added 36.73% | +$2.51M | $9.35M | 0.30% | Jul 10, 2026 |
| SEB Asset Management AB | Added 38.71% | +$2.46M | $8.83M | 0.03% | Aug 4, 2026 |
| Gilder Gagnon Howe & Co LLC | Sell 100% | -$2.01M | $0 | 0.00% | Aug 14, 2026 |
| AIHC Capital Management Ltd | Sell 100% | -$1.98M | $0 | 0.00% | Aug 13, 2026 |
| Harvest Investment Services, LLC | Sell 100% | -$1.96M | $0 | 0.00% | Aug 14, 2026 |
| Fiera Capital Corp | Reduce 8.32% | -$1.8M | $19.8M | 0.07% | Aug 7, 2026 |
| Persistent Asset Partners Ltd | Added 49.46% | +$1.77M | $5.35M | 1.60% | Aug 7, 2026 |
| Handelsbanken Fonder AB | New Buy | +$1.73M | $1.73M | 0.00% | Jul 10, 2026 |
| Sphera Funds Management Ltd. | Added 10.33% | +$1.66M | $17.8M | 2.32% | Aug 14, 2026 |
| Platinum Investment Management Ltd | Added 37.62% | +$1.63M | $5.97M | 1.47% | Aug 13, 2026 |
| Capricorn Fund Managers Ltd | New Buy | +$1.6M | $1.6M | 0.13% | Jul 24, 2026 |
| Defilade Capital Management, L.P. | Added 11.59% | +$1.58M | $15.2M | 2.04% | Aug 14, 2026 |
| Nomura Asset Management International Inc. | Added 10.80% | +$1.48M | $15.2M | 0.02% | Aug 14, 2026 |
| Rafferty Asset Management, LLC | Reduce 29.63% | -$1.43M | $3.4M | 0.01% | Aug 14, 2026 |
| VANGUARD ASSET MANAGEMENT, Ltd | Added 42.10% | +$1.43M | $4.82M | 0.00% | Aug 13, 2026 |
| Castleark Management LLC | Added 56.17% | +$1.39M | $3.86M | 0.10% | Aug 14, 2026 |
| Jain Global LLC | New Buy | +$1.36M | $1.36M | 0.01% | Aug 14, 2026 |
| Silverarc Capital Management, LLC | Reduce 2.55% | -$1.3M | $49.6M | 5.15% | Aug 13, 2026 |
| Capital Fund Management S.A. | New Buy | +$1.07M | $1.07M | 0.00% | Aug 13, 2026 |
| Cinctive Capital Management LP | Reduce 37.90% | -$1.01M | $1.65M | 0.06% | Aug 14, 2026 |
| Peregrine Capital Management LLC | Added 12.08% | +$944K | $8.76M | 0.28% | Jul 17, 2026 |
| Osterweis Capital Management Inc | Added 14.11% | +$823K | $6.66M | 0.31% | Aug 14, 2026 |
| Atika Capital Management LLC | Reduce 7.23% | -$820K | $10.5M | 0.69% | Aug 13, 2026 |
| Fisher Asset Management, LLC | Added 10.43% | +$676K | $7.15M | 0.00% | Aug 4, 2026 |
| Emerald Advisers, LLC | Added 0.96% | +$588K | $62M | 1.46% | Aug 5, 2026 |
| Fox Run Management, L.L.C. | Added 228.94% | +$514K | $738K | 0.12% | Aug 4, 2026 |
| ADAR1 Capital Management, LLC | New Buy | +$472K | $472K | 0.02% | Aug 14, 2026 |
| Virtus Advisers, LLC | New Buy | +$446K | $446K | 0.17% | Aug 11, 2026 |
| Knights of Columbus Asset Advisors LLC | Added 28.48% | +$430K | $1.94M | 0.10% | Jul 31, 2026 |
| State of New Jersey Common Pension Fund D | Added 38.55% | +$427K | $1.54M | 0.01% | Aug 4, 2026 |
| Vanguard Investments Australia, Ltd. | Added 52.97% | +$419K | $1.21M | 0.00% | Aug 13, 2026 |
| Profund Advisors LLC | Reduce 18.97% | -$419K | $1.79M | 0.05% | Aug 11, 2026 |
| Axq Capital, LP | Sell 100% | -$417K | $0 | 0.00% | Aug 6, 2026 |
| Tidal Investments LLC | Added 4.32% | +$387K | $9.35M | 0.02% | Aug 13, 2026 |
| KLP Kapitalforvaltning As | Added 50.27% | +$360K | $1.08M | 0.00% | Aug 12, 2026 |
| CenterBook Partners LP | New Buy | +$320K | $320K | 0.02% | Aug 11, 2026 |
| HighVista Strategies LLC | Reduce 4.20% | -$320K | $7.31M | 1.67% | Aug 14, 2026 |
| Bridgefront Capital, LLC | New Buy | +$308K | $308K | 0.08% | Aug 14, 2026 |
| University of Texas/Texas Am Investment Management Co | New Buy | +$290K | $290K | 0.03% | Aug 3, 2026 |
| Swiss Life Asset Management Ltd | New Buy | +$283K | $283K | 0.00% | Jul 29, 2026 |
| FORA Capital, LLC | Sell 100% | -$283K | $0 | 0.00% | Aug 13, 2026 |
| Knott David M Jr | Added 6.81% | +$274K | $4.3M | 2.27% | Aug 12, 2026 |
| Kennedy Capital Management LLC | Reduce 1.86% | -$259K | $13.7M | 0.24% | Aug 14, 2026 |
| &Partners | New Buy | +$255K | $255K | 0.00% | Aug 14, 2026 |
| Allstate Corp | New Buy | +$252K | $252K | 0.00% | Aug 13, 2026 |
| DNB Asset Management AS | New Buy | +$242K | $242K | 0.00% | Aug 11, 2026 |
| 49 Wealth Management, LLC | Sell 100% | -$239K | $0 | 0.00% | Aug 18, 2026 |
| Macquarie Group Ltd | New Buy | +$213K | $213K | 0.00% | Aug 14, 2026 |
